Am stoked and thrilled that our latest paper is now out. A longitudinal study of invasive E. coli from children in the Netherlands over 50 years www.sciencedirect.com/science/arti...

Important study by Chris Connor and Ben Howden (both not on here?) @unimelb.edu.au 'Global dissemination of optrA-mediated linezolid resistance in enterococci', major roles of mobile genetic elements in the dissemination of this important resistance determinant academic.oup.com/jac/article/...

If you check out my lab's recent work, you'll notice how much biofilm structure is destroyed by dehydration & vacuum during standard scanning electron microscopy. These are both images of P. aeruginosa PA14 #biofilm on pig lung tissue at 48h p.i: using cryoSEM retains the biofilm matrix. #MicroSky

Paper out! We used RNAseq to track changes in P. aeruginosa gene expression over 7 days of #biofilm infection in our #CysticFibrosis lung model. www.microbiologyresearch.org/content/jour... #MicroSky (1/n)

I’ve spent a lot of time over the past two years thinking about genome evolution and how recent research revealing complex gene-gene interactions has complicated traditional ‘gene-centric’ genomic approaches to evolution. So here is a review that consolidates these thoughts! rdcu.be/e6pHY

New paper from us. If you're interested in genetic manipulation of Clostridia, we have a few new tools for you! 36 new plasmids - all available from @addgene.bsky.social www.microbiologyresearch.org/content/jour... #microsky

Amazing work from @freyaallen.bsky.social and @prob91.bsky.social. I truly believe that Rob is the Sherlock Holmes of MGEs and one of the leaders in the field of artisanal bioinformatics😉!

Our new paper in MGen traces the evolution of a plasmid lineage associated with MDR in Enterococcus faecium, primarily driven by IS1216 For anyone interested in plasmid structures and the smaller MGEs that shape them 🧵👇 [1/14] @microbiologysociety.org www.microbiologyresearch.org/content/jour...

Delighted that our review on resistance to last-resort antibiotics in Enterococci has been published in FEMS Microbiology Reviews academic.oup.com/femsre/advan... (accepted manuscript version) TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.

Absolutely delighted (and proud) that @freyaallen.bsky.social passed her viva with minor corrections today. Thanks very much @jessicamablair.bsky.social @robfagan.bsky.social for examining!

🚨New pre-print 🚨 We introduce our new tool GOLD-GWAS and demonstrate its use by digging into the evolution of MRSA facilitated by SCCmec This work was led by talented PhD student @seungwonko.bsky.social who did most of the computational heavylifting 1/n www.biorxiv.org/content/10.1...

🚨 New preprint klaxon 🚨 We characterised the structure of a PNGaseA superfamily member from Bifidobacterium bifidum LMG13195 and highlight its preference for N-glycan structures attached to a peptide, rather than to a native or denatured protein 💫 @imibirmingham.bsky.social

New manuscript from the group 'IS1216 drives the evolution of pRUM-like multidrug resistance plasmids in Enterococcus faecium' www.biorxiv.org/content/10.1... /1