Humbled

Exited to see this preprint led by Tammy Lan in the Sabeti Lab using spatial transcriptomics to study the impacts of aging on the cycling ovaries. www.biorxiv.org/content/10.1...

🧬 Genomic DNNs can be trained to learn a lot of different aspects of gene regulation, but they're not perfect and we don't know which predictions are reliable and which ones aren't. We introduce DEGU: Uncertainty-aware Genomic Deep Learning with Knowledge Distillation. 1/n

Pleased to share our latest work on genomic- and methylation-based #ctDNA analysis of baseline samples from patients with #DDR and #HRD tumors. New insights into tumor fraction estimation, HRD signatures, and reversion alterations including novel reversions in #ATM www.medrxiv.org/content/10.1...

Biology of Genomes 2025 is coming up: - meeting dates: May 6 - 10, 2025 - abstract deadline: Feb 14, 2025 We hope to see you there for another great meeting with a fantastic speaker lineup! meetings.cshl.edu/meetings.asp...

Kicking off this account by sharing our paper “Machine-guided design of cell-type-targeting cis-regulatory elements” published just over a month ago www.nature.com/articles/s41... #genomics #syntheticbiology #AI