A #DNA-based nanoplatform targets gums with curcumin and defensin to combat infection, inflammation, and #bone resorption. This clean system boosts therapeutic efficacy against periodontal and related bone-wasting disorders.👍 @ijosjournal.bsky.social www.nature.com/articles/s41...

#Oral #cancer is rising in non-smokers. Body aging and germs, not tobacco, drive two hidden #tumor subtypes. First #molecular profiling redefines early detection and prevention for low-risk patients.🥳 @ijosjournal.bsky.social www.nature.com/articles/s41...

A gut bacteria compound (tributyrin) relieves jaw joint pain by restoring brainstem gene activity damaged by chronic pain. This gut-brain link could replace addictive painkillers with safer, non-habit-forming therapies for jaw joint disorders. @ijosjournal.bsky.social www.nature.com/articles/s41...

Wisdom #teeth often damage neighboring molars and cause painful infections. New expert #guidelines standardize when removal is truly needed, helping #dentists avoid unnecessary surgery while protecting #oral health.🦷 @ijosjournal.bsky.social www.nature.com/articles/s41...

#SLIT3 promotes #dental stem cell proliferation and mineralization via a key pathway, enabling targeted molecular regulation for clinical root/dentin regeneration and advancing next-generation #biological tooth repair.😀 @ijosjournal.bsky.social www.nature.com/articles/s41...

Taste sensors in the mouth also exist in lungs and gut, controlling immune responses and metabolism. Understanding these dual roles could offers new therapeutic avenues for diabetes, asthma, and immune disorders beyond dietary interventions.😀 @ijosjournal.bsky.social www.nature.com/articles/s41...

Severe gum disease is three times more common in people with early kidney disease. Treating gum inflammation could help protect kidney health, offering a simple way to catch and slow kidney decline early.👍 #gum #oral #kidney @ijosjournal.bsky.social www.nature.com/articles/s41...

A sugar coating on proteins controls how facial bones fuse during pregnancy. When disrupted, it causes cleft palate. Understanding this process could lead to early screening and prevention for this common birth defect.😀 #oral #proteins @ijosjournal.bsky.social www.nature.com/articles/s41...

The mouth contains diverse stem cells that build teeth, roots, and gums. Mapping these cell types advances regenerative dentistry, potentially enabling living tooth repair and gum regeneration without implants.👍 #mouth #oral #teeth @ijosjournal.bsky.social www.nature.com/articles/s41...

Expert consensus establishes guidelines for bone grafting during adult orthodontic treatment. This framework helps clinicians safely rebuild jawbone, expand tooth movement options, and reduce periodontal risks where bone defects previously limited treatment.👍 www.nature.com/articles/s41...

Jaw joint arthritis causes hidden damage like fat buildup and scarring in the disc. Understanding these early cellular changes could enable targeted therapies to prevent severe joint deterioration, advancing treatment beyond pain management.👇 @ijosjournal.bsky.social www.nature.com/articles/s41...

Two proteins (Gli2 and Gli3) team up to build tooth roots by guiding stem cell growth. Mapping this process reveals how facial structures form and could enable regenerative therapies for dental defects and craniofacial disorders.😀 @ijosjournal.bsky.social www.nature.com/articles/s41...

A cellular signaling pathway (JAK-STAT) controls how jaw and face bones grow. When it malfunctions, severe facial deformities result. Existing drugs like baricitinib could treat these conditions, offering new precision therapy options and avoiding complex surgeries.👍 www.nature.com/articles/s41...

A novel engineered peptide (TKH) seals exposed tooth tubules and rebuilds dentin through self-assembly, offering a biocompatible long-term fix for sensitive teeth without harsh chemicals.👍 #tooth #oral #dental #biocompatible @ijosjournal.bsky.social www.nature.com/articles/s41...

KDM6B is a molecule drives tooth root repair by boosting lactate production. This metabolic mechanism suggests simple lactate supplements could reverse damage from severe gum disease.👍 #KDM6B #tooth #oral #lactate @ijosjournal.bsky.social www.nature.com/articles/s41...

Researchers used a drug to transform stem cells into enamel-producing cells, creating tooth enamel without natural cell contact. This could enable living tooth repair for adults who cannot naturally regenerate damaged enamel.👍 #tooth #enamel @ijosjournal.bsky.social www.nature.com/articles/s41...

ANKRD1 is a chromatin regulator that preserves bone marrow stem cells' ability to become neurons. Its decline with age drives cognitive decline. Restoring it benefits memory and could transform approaches to cognitive aging.😀 #ANKRD1 #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Scientists mapped how immune cells attack jaw cartilage in arthritis via specific damage signals. Blocking these pathways shows therapeutic potential, offering precise drug targets for treating this painful jaw condition.🤓 #jaw #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Scientists identified a rare stem cell type (GLDN+) in dental pulp that builds teeth and blood vessels. These cells could enable living tooth repair, offering an alternative to artificial fillings and implants.👍 #dental #oral #teeth @ijosjournal.bsky.social www.nature.com/articles/s41...

Two active bacteria found deep in children's cavities may drive severe tooth decay. Targeting these microbes could lead to better treatments for early childhood caries.😀 #tooth #microbes #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Dental implants prevent jawbone loss by triggering a protein called sorting nexin 5 (Snx5). This discovery could improve implant success and lead to new bone healing treatments.😀 #Snx5 #jawbone #dental @ijosjournal.bsky.social www.nature.com/articles/s41...

Dentists face 3.6 times higher vision risks due to chronic exposure to bright dental lights, with blue and white LEDs damaging blood-retinal barriers. Switching to low-intensity halogen lighting could protect dentist eye health.👀 #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Excess copper triggers "cuproptosis"—a unique cell death that destroys bone by blocking sugar storage. This copper-sugar link explains bone loss in gum disease and suggests new treatments for copper-related bone conditions.😀 #copper #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Enamel's toughness comes from its unique crisscross pattern, now explained by cell sliding during formation. This insight could lead to stronger dental materials.👍 #enamel #dental #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Oral cancer cells in a hybrid state drive spread and resist treatment. Targeting this partial-Epithelial-Mesenchymal Transition (EMT) state could improve therapies, potentially boosting patient survival and quality of life.👇 #cancer #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Gum disease bacteria worsen osteoporosis through the gut, but a natural compound called ILA can stop bone loss by blocking bone-breakdown cells, offering new therapy for people with both conditions.👇 #gum #bacteria #ILA @ijosjournal.bsky.social www.nature.com/articles/s41...

Childhood tooth anomalies impair function, development, and mental health. New expert consensus provides standardized diagnosis and treatment guidelines, promoting early intervention and improving lifelong outcomes.🤓 #tooth #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

A genetic variant in Oral Squamous Cell Carcinoma (OSCC) affects cell growth by altering RNA splicing, offering a new treatment target that could potentially improve outcomes by specifically addressing this molecular pathway.😀 #OSCC #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Wnt3a activates dental stem cells, guiding them to become odontoblasts and repair teeth. This breakthrough could lead to regenerative treatments for damaged teeth, potentially reducing the need for extractions or implants and advancing dental care.👍 #Wnt3a #dental www.nature.com/articles/s41...

MARCH2 protein's role in slowing tooth development could lead to more targeted dental treatments, potentially reducing the need for extractions and improving oral health.🤓 #MARCH2 #tooth #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Chronic Obstructive Pulmonary Disease (COPD) worsens with periodontitis, as bacteria travel to the lungs, causing more inflammation. Understanding this link can improve treatment strategies.🤓 #COPD #periodontitis @ijosjournal.bsky.social www.nature.com/articles/s41...

SMAD Family Member 7 (SMAD7) is a protein vital for tooth stem cells' growth and differentiation. Understanding its role could revolutionize dental tissue regeneration and repair strategies, leading to better oral health treatments.🥳 #SMAD7 @ijosjournal.bsky.social www.nature.com/articles/s41...

Next-gen skull implants use smart materials and 3D printing for personalized, safer bone fixes. AI and real-time tech promise even better outcomes.😀 #AI #3D #bone #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

A specific protein in cavity-causing bacteria, SmFtsZ, revealed to resist acid with a unique structure. Targeting this could prevent tooth decay and guide new treatments.😀 #tooth #SmFtsZ @ijosjournal.bsky.social www.nature.com/articles/s41...

CILK1, a protein in cell structures called primary cilia, helps regulate tooth development. Researchers used mice to discover that lacking CILK1 causes extra or fused teeth, highlighting its crucial role in tooth development and potential impact on human dental health. www.nature.com/articles/s41...

Arginine, an amino acid, can change how bacteria stick together and affect acidity. A study shows it helps fight cavities by keeping pH stable and changing plaque structure, offering new ways to prevent tooth decay.🦷 #Arginine #tooth #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Interleukin 17（IL-17）is a key protein in our immune system. A study shows it can worsen mouth infections and affect blood sugar levels. Targeting IL-17 could improve glycemic control and reduce type 2 diabetes risk😀 #Interleukin17 #diabetes @ijosjournal.bsky.social www.nature.com/articles/s41...

Exploring ferroptosis in tooth pulpitis, a new study reveals cellular differences using single-cell RNA sequencing. Thymosin α1 shows promise in reducing inflammation and treating pulpitis.👇 #ferroptosis #oral #Thymosinα1 @ijosjournal.bsky.social www.nature.com/articles/s41...

By using RNA sequencing to map tooth development, a new study shows lingual cells build teeth while buccal cells support tissues, guiding future dental regeneration strategies.😀 #RNA #tooth #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Check out our video!🥳PLAGL1-IGF2 axis regulates osteogenesis of postnatal condyle development #PLAGL1 #IGF2 #osteogenesis @ijosjournal.bsky.social www.nature.com/articles/s41...

New injectable hydrogel promotes pulp-dentin complex repair and nerve regrowth, offering a promising strategy for functional dental tissue regeneration.👇 #hydrogel #dental #tissue #oral @ijosjournal.bsky.social www.nature.com/articles/s41...

Research reveals PLAGL1, a key gene, boosts jawbone growth via the IGF2 pathway, aiding bone-forming cells. Vital clues for treating craniofacial issues!👍 #PLAGL1 #IGF2 #jawbone #gene @ijosjournal.bsky.social www.nature.com/articles/s41...

Featured in IJOS's [Top 5 Articles in the first half of 2025]😀：Recent study uncovers how Fusobacterium nucleatum fuels oral cancer growth, revealing potential targets to inhibit its harmful effects and improve treatments!👍 #oral #cancer @ijosjournal.bsky.social www.nature.com/articles/s41...

Featured in IJOS's [Top 5 Articles in the first half of 2025]🥳：LSD1 is a protein that promotes cancer. Recent study shows inhibiting LSD1 can reverse early cancer changes and boost immune response, offering a new strategy for oral cancer treatment！👍 #LSD1 #cancer www.nature.com/articles/s41...

Featured in IJOS's [Top 5 Articles in the first half of 2025]🥳：This review explores the mechanisms behind oral submucous fibrosis (OSF) and discusses potential therapeutic strategies, offering new hope for treating this chronic fibrotic disease.👇 #oral #dental www.nature.com/articles/s41...

Featured in IJOS's [Top 5 Articles in the first half of 2025]🥳 Apical microsurgery is a precise, minimally invasive dental procedure with over 90% success rate. A new consensus helps dentists understand and perform it better.👇 #oral #dentist @ijosjournal.bsky.social www.nature.com/articles/s41...

[2025 Top 5 Featured Article]—a must-read for ortho clinicians & researchers! 🥳Clear aligners offer a new orthodontic treatment option! This expert consensus provides a comprehensive guide on their use, aiming to enhance treatment efficacy and promote wider adoption. www.nature.com/articles/s41...

Researchers find that a special RNA called JPX boosts a cancer gene in head and neck cancer, affecting how tumors grow and interact with the immune system. Drugs Axitinib and Palbociclib might help treat this type of cancer.👍 #JPX #Axitinib @ijosjournal.bsky.social www.nature.com/articles/s41...

Check out our video!🥳Expert consensus on the treatment of oral diseases in pregnant women and infants #oral #pregnant #infants @ijosjournal.bsky.social www.nature.com/articles/s41...

Title correction: Study reveals Nogo-A, a protein involved in neural development, plays a key role in tooth enamel formation, offering new insights into dental health and potential treatments！👍 #tooth #oral #dental @ijosjournal.bsky.social www.nature.com/articles/s41...