Congratulations to BLS Lecturer Dr Amy Saunders who has co-authored research featured on the front cover of this week's issue of #ScienceSignaling! Dr Saunders' research has updated our understanding of how glycans help immune cells move into skin in psoriasis. www.science.org/doi/10.1126/...

Congratulations to Prof Alona Armstrong of Lancaster Environment Centre for being named on The ENDS Report's Power List 2025, which spotlights the environmental professionals who have made the greatest impact in the past two years 🌍💡 @alona-armstrong.bsky.social | @endsreport.com

Closing on soon - you have until the 14th to apply for our interdisciplinary PhD studentship - develop new cell-based infection models & AI analysis to study infections and discover antimicrobials. Link below.

New online: Transcription stress causes an inflammatory response via release of IL-1α

We have written a News&Views piece in @natsmb.nature.com on a recent paper by @buissonlab.bsky.social. Their work adds transcription stress to the landscape of danger signals detected by the innate immune system. Link for free access here: rdcu.be/ehkTV

Today @naturesmb.bsky.social 🥳, we report that the activation of NF-κB after DNA damage can occur through two distinct mechanisms. While ATM triggers NF-κB activation after DSBs, we found that IRAK1 specifically induces NF-κB in response to DNA damage causing transcriptional stress.

Pre-print alert! Together with @stapleslab.bsky.social and @cejkalab.bsky.social we find that IFI16 binds to stalled replication forks where it acts as innate immune sensor for replication stress, and protects the nascent DNA from degradation. 👇👇