#MicroSky: The HNH endonuclease HrdP is a highly conserved and essential determinant of infectivity among Skunavirus phages, required for successful completion of DNA packaging. HrdP is a promising and specific anti-phage target to protect dairy starter cultures from failure. doi.org/10.1111/1751...

#MicroSky: This study offers a novel strategy for optimizing the synergistic fermentation of L. plantarum and phenylethyl acetate, thereby enhancing alfalfa silage flavor quality & promoting sheep feed intake. Read Fu et al. doi.org/10.1111/1751...

Crucial Gram-positive Type IV Secretion System protein TraF is a structural homolog of Type VII Secretion System protein EssB/YukC in #microLife @femsjournals.bsky.social academic.oup.com/microlife/ad...

#MicroSky: Turning fungi into insulin factories! Yan et al in Microb. Biotechnol. report that engineered Trichoderma unlocks efficient secretion of insulin glargine with high yields and bypassing stress. This paves the way for scalable production of complex therapeutics! doi.org/10.1111/1751...

#Agricultural #soils exposed to controversial #weedkiller may be unexpected breeding ground for hospital #superbugs ... | #antimicrobialresistance | #MicroSky | #bacteria | #AMR | #antibiotics | By @frontiersin.bsky.social via @sciencex.bsky.social

#MicroSky:Alcohol dehydrogenase in Candida isn’t just metabolic, it’s a morphogenesis regulator. Knocking it out drives hyperfilamentation, block hyphae & biofilms development by modulating SNF1 signaling.A new antifungal strategy emerges: hit virulence via metabolic enzymes! doi.org/10.1111/1751...

#Microsky: New insights into fungal biocontrol and new targets for smarter plant disease management. The bZIP63.5 master regulator of Trichoderma boost antifungal power by blocking defense networks in Alternaria. Read Yang et al doi.org/10.1111/1751...

#MicroSky: Next Generation probiotics: S. clusii is a resilient G(+) spore-former with high potential for biotherapeutics & biotech. A new electropretion method + versatile shuttle vectors now unlock fast, scarless genome editing. Don’t miss Capella et al doi.org/10.1111/1751...

Everything you need to explain mycorrhizal fungi to family-friends (also in Hindi) @michela-audisio.bsky.social @frewecologist.bsky.social @katiefield4.bsky.social @mycorrhizaims.bsky.social @balachaudhary.bsky.social @fungidownunder.bsky.social @cmarin.bsky.social imili.org/pdf/Mycorrhi...

#MicroSky: Probiotic benefits are clear, but survival in the gut is not! Advanced microencapsulation protect probiotics from acid, bile & stress enabling targeted intestinal release and paving the way for safer & more effective therapies. enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....

#MicroSky: Cleaner soils through Microbial evolution. Paenarthrobacter degrades the fungicide iprodione via IpaH/DhaH and DuaH. Comparative analysis revealed gene duplication, Horizontal Gene Transfer and pathway evolution by environmental exposure. doi.org/10.1111/1751...

#MicroSky: Chronic Spontaneous Urticaria (CSU) is linked to gut dysbiosis and elevated serum uric acid/hypoxanthine. Lactobacillus paragasseri LG-1 alleviates urticaria by degrading these metabolites, inhibiting TLR4-NF-κB inflammation, and remodeling gut microbiota. doi.org/10.1111/1751...

#MicroSky: Bacterial & archaeal communities power plant-microbial fuel cells. Bueno-freire et al integrates current knowledge through comprehensive tables & knowledge graphs, emphasizes microbial diversity, functions & biotechnological potential for renewable energy use. doi.org/10.1111/1751...

#MicroSky: Acinetobacter ADP1 & its glyoxylate shunt mutant, grow on short-chain fatty acids and directly on acidogenic fermentate from arrested anaerobic digestion of biomass. Compositional control of the fermentate results in different growth and wax accumulation behaviour. doi.org/10.1111/1751...

#MicroSky: Cao et al show in MBT how tiny genetic changes can flip bacteria life style. In Zymomonas mobilis, a single amino acid swap reshaped movement versus sticking together. They show how small DNA tweaks can rapidly rewire bacterial behaviour and evolution. Don’t miss doi.org/10.1111/1751...

#MicroSky: Fernández et al show that bacteria don’t just adapt by mutating genes, but they also tweak genes switches. In Salmonella structured changes in the opvAB promoter fine-tune surface traits, revealing a new layer of evolutionary adaptation beyond DNA coding changes. doi.org/10.1111/1751...

Investigadores de la Universidad de Granada desarrollan córnea artificial de bajo coste a partir de escamas de peces comunes con resultados prometedores. ecoinventos.com/investigador...

One of the biggest challenges in microbial biotechnology? Unlocking the potential of non-model microbes and synthetic communities! Glad to share our review @sonjablasche.bsky.social @simonemozzachiodi.bsky.social @kiranrpatil.bsky.social @cambridgebiosci.bsky.social🧵(1/7) doi.org/10.1016/j.co...

#MicroSky: GREEN AGRICULTURE: Wood hemicelluloses from forestry waste can microencapsulate phages for storage & delivery. Against Ralstonia solanacearum, these capsules boost soil stability and enhance anti-bacterial wilt activity. READ Negroni et al doi.org/10.1111/1751...

#MicroSky: Root-associated microbiota help shape crop architecture. Chen et al introduce “holobiont architecture,” where plant form is dynamically tuned through plant–microbiome synergy, offering new paths to breed resilient, architecture-smart crops. Don’t miss MBT at doi.org/10.1111/1751...

#MicroSky: Xie et al describe a novel cumate-inducible promoter, Pgc, that was engineered in K. pastoris by optimising the CuO operator and CymR repressor (A). This system achieved an approximately 11-fold increase in recombinant protein production upon induction (B). doi.org/10.1111/1751...

#MicroSky: GREEN AGRICULTURE: Microbial VOCs can support sustainable crop protection, yet practical implementation remains limited. Belt et al propose practical and technological pathways to bridge the gap between laboratory discoveries and on-farm deployment. doi.org/10.1111/1751...

valuing education (and this requires valuing teachers and investing in them and the infrastructure needed): www.weforum.org/stories/2026...

Now available on Zenodo (doi: 10.5281/zenodo.18365874). Discover how tiny microbes keep our water clean

New gallery alert! Meet the Micro-Heroes of wastewater on the IMiLi website, led by Victor Hernando-Morales. Discover how tiny microbes clean our water: breaking down waste, removing nutrients, and neutralizing toxins. Invisible work, massive impact. grupos.eez.csic.es/imili/wp-con...

#MicroSky: Khan et al report that E. cloacae thrives in chlorinated marine cooling systems, evolving cross-resistance and biofilms that promote barnacle settlement. A native bacteriophage disrupts these biofilms, reducing fouling, offering a sustainable control strategy. doi.org/10.1111/1751...

#MicroSky: Antibiotic resistance crisis: Ansari & Nagar isolated jumbo lytic phage P19 targeting MDR Aeromonas. Its T4-type endolysin shows broad antibacterial activity across MDR Gram-negatives, highlighting phages as promising alternatives to antibiotics. doi.org/10.1111/1751...

#MicroSky: Since its discovery in 1983, HIV/AIDS treatment has evolved from daily pills to powerful prevention tools. Long-acting shots like cabotegravir (every 2 months) and lenacapavir (every 6 months) could game-changers, if access and cost barriers are overcome. doi.org/10.1111/1751...

Also available on Zenodo: 10.5281/zenodo.18352194. Illustrated: Antibiotic susceptibility testing disk diffusion showing that this “pan-resistant” or superbug bacterial strain is resistant to all tested antibiotics.

A lesson for all audiences on the crisis of antimicrobial resistance: a story of ignored warnings, by Felipe Cabello and Henry Godfrey, in our IMILI Thematic Framework series (grupos.eez.csic.es/imili/wp-con...). Source of the image: Wikipedia

#MicroSky: AQUACULTURE: A new tool for sustainable aquaculture. Synechocystis extracellular vesicles function as stable, immune-stimulating nanocarriers with adjuvant activity. Marthina-Cardoso et al open a door to next-gen fish vaccines. In MBT doi.org/10.1111/1751...

#MicroSky: Green Biochemistry: Hybrid beats monoculture! Zini et al engineered a cyanobacterium into a natural photosynthetic microbiome, boosting resilience, scalability & PHB bioplastic production. A novel robust platform for industrial biotech. doi.org/10.1111/1751...

#MicroSky: Green Chemistry: Plant cells & microbes = better chemistry. Co-culturing plant cells with immunity-activating endophytic bacteria reshapes metabolism without inhibiting growth, trigger defense genes and produce phytochemicals. A promising biotech platform. doi.org/10.1111/1751...

#MicroSky: Probiotic Lactobacillus salivarius Li01 alleviates acute pancreatitis in mice by reshaping the gut microbiota, boosting steroid hormone–related metabolites, and dampening inflammatory pathways (incl. TNF-α) along the gut–pancreas axis. Read Duan, Lou et al in MBT. doi.org/10.1111/1751...

#Microsky: Repurposing the endogenous type II-A CRISPR–Cas system in Lacticaseibacillus rhamnosus GG enables efficient genome engineering making it a programmable chassis for functional strain development in food biotechnology, precision fermentation & live biotherapeutics. doi.org/10.1111/1751...

#MicroSky: Tens of thousands of microbial BGCs are known, but most natural products remain unlinked. By adding phylogeny to metabologenomics, Bolt et al cut false links 33× and uncovered new BGC–metabolite matches, powering scalable natural product discovery. doi.org/10.1111/1751...

#MicroSky: Directed evolution rewired AlkS to sense isobutanol with high specificity. Fine-tuning via mutagenesis and promoter engineering boosted the biosensor sensitivity 114%. A strong platform for high-throughput screening of alcohol-producing strains. Read Chen et al doi.org/10.1111/1751...

Behind many breakthroughs in microbiology are women whose impact outpaced their recognition. To celebrate #IDWGS, we are bringing attention to their work. And the work continues. Nominate a female microbiologist we should interview for our community blog: buff.ly/kk7Ieye

Mapping the #hydrogel properties that control #bacterial growth ... | #microbes | #bacteria | #Escherichia | #Pseudomonas | #Staphylococcus | #Bacillus | #antibioticresistance | By @uni-of-warwick.bsky.social via @sciencex.bsky.social

#MicroSky: ONE HEALTH: Betulinic acid combats Staphylococcus aureus biofilms on implants by blocking adhesion and EPS/eDNA formation, boosting immune clearance. It reduces inflammation, enhances type I collagen & accelerates wound healing. Read in MBT at doi.org/10.1111/1751...

#MicroSky: CIRCULAR ECONOMY: Thermal cycling & fungal inoculants (Fomes lignosus & Penicillium glabrum) reshape compost microbiomes, boosting humification with 5% increase in carbon conversion & humic acid yield. A smart path for lignocellulosic waste valorization! Read doi.org/10.1111/1751...

#MicroSky: Extremophiles: Unlocking genetics in Halomonas. A highly efficient electroporation protocol for Halomonas elongata boosts transformation success and works across strains. A new door to genetic studies in underexplored species. Read Coimbra et al: doi.org/10.1111/1751...

#MicroSky: PHAGES & BIOTECH. Bao et al show that previously overlooked phages drive microbial life-history trade-offs, shape organic matter transformation, and enhance soil carbon stability in agricultural ecosystems. Read Microb Biotechnol. doi.org/10.1111/1751...

#MicroSky: ENVIRON BIOTECH: Vidal et al discuss that deep beneath Earth’s surface, life thrives in extremes. Subsurface microbiology reveals the limits and origins of life, and guides the search for biosignatures on Mars, icy moons, and distant exoplanets. Do not miss doi.org/10.1111/1751...

#MicroSky: ENVIRON BIOTECH: Selenium detox meets green nanotech. Stenotrophomonas converts toxic Se oxyanions into antimicrobial selenium nanoparticles with strain-specific killing mechanisms. Biogenic SeNPs are eco-friendly, broad-spectrum antimicrobials. doi.org/10.1111/1751...

#MicroSky: FERMENTATION: Acetic acid buildup can spoil fermentations—but real-time detection is hard. A whole-cell bacterial biosensor enables low-cost, sensitive, headspace AC monitoring supporting early intervention & better quality control. The future ahead by Kesler et al doi.org/10.1111/1751...

#MicroSky: ONE HEALTH: Type 2 diabetes is linked to the gut microbiota: Probiotics, prebiotics, synbiotics & fecal microbiota transplantation show promise in restoring microbial balance and improving metabolic health. Learn about new avenues for prevention and therapy. doi.org/10.1111/1751...

#MicroSky: BIOTECH-ENVIRONMENT: Rising CO₂ demands smarter biomanufacturing. A gas-linked co-culture pairing heterotrophs with autotrophs recycles emitted CO₂, nearly doubles PHB & carotenoid output, and cuts net CO₂ by >20%. Learn about novel circular carbon biorefineries. doi.org/10.1111/1751...

Photoholes within cyanobacterial mats can account for the origin of #anammox bacteria and ancient #nitrogen loss link.springer.com/article/10.1...

#MicroSky: Microbial Literacy: In a world of cascading, human-made crises & information overload, better decisions are urgent. Critical thinking, taught early & practiced widely, is our best defense against bias, misinformation, and self-harm to society and planet. doi.org/10.1111/1751...