PhD student position in laboratory of Christa E Fluck @dbmr-unibe.bsky.social @unibe.ch @medfacultyunibe.bsky.social 📢Laboratory details: lnkd.in/eND9EV-G 📄 Details: lnkd.in/eVrN-z3G Funding: @snsf.ch #Genetics #Endocrinology #OMICS #DSD #SexDevelopment #WES #Long-Read_Sequencing

🚀New Publication by @pandeylab.bsky.social @medfacultyunibe.bsky.social @dbmr-unibe.bsky.social @unibe.ch ! 🇨🇭🔬 🌿Dihydrotanshinone (DT) as a potent, selective CYP17A1 lyase inhibitor blocks androgen production 📊 #PCOS & #prostatecancer. Cancer Research Switzerland. 📄 doi.org/10.3390/biom...

Can we stop androgen excess without crashing cortisol? 🤔 YES 🎯. Dihydrotanshinone (DT), inhibits CYP17A1 lyase (androgens) not hydroxylase (cortisol). A huge step forward for safer PCOS & CAH therapies. 🌿💊 Read more: doi.org/10.20944/pre... #PCOS #Science #DrugDiscovery

New paper @pandeylab.bsky.social @dbmr-unibe.bsky.social @unibe.ch ! 🧬 Mapped functional epitopes of Human Growth Hormone for molecular "Danger Zones" in growth disorders solving paradox of "bioinactive" GH hormones. 🧵👇 [https://www.mdpi.com/1467-3045/47/12/1012] #ESKAS @novo-nordisk.bsky.social

Kick off Project GUITAR! 🎸🧬in Translational Hormone Research Program of @dbmr-unibe.bsky.social Tackling Congenital Adrenal Hyperplasia by "smart" inhibitors by ✅AI-driven Design ✅ Structural Biology ✅ European collaboration (🇨🇭🇵🇱🇩🇰)🚀 #RareDisease Funding by @medfacultyunibe.bsky.social @unibe.ch

🔬 @pandeylab.bsky.social , @unibe.ch study in #JCEM @endosocjournals.bsky.social novel POR G88S mutation causing severe #PORD. 🧬 Beyond the disorder, this mutation creates a critical pharmacogenomic risk 💊⚠️ gene-to-clinic story: doi.org/10.1210/clin... #Endocrinology #RareDisease

Congratulations to PhD student Jubira Yakubu from @pandeylab.bsky.social of @dbmr-unibe.bsky.social @medfacultyunibe.bsky.social @unibe.ch for winning the Best Presentation Award at the Annual Research Conference of Children's Hospital. Big thank you to Cancer Research Switzerland for funding.

PhD Student in Molecular and Translational Medicine: Dissecting & Targeting a Human Metabolic Disorder funded by @snsf.ch in @pandeylab.bsky.social @unibe.ch @medfacultyunibe.bsky.social @dbmr-unibe.bsky.social

Postdoctoral Research Position on modulation of human steroid and drug metabolism by redox proteins like P450 oxidoreductase (POR), Ferredoxin reductase (FDXR), ferredoxin (FDX1). funded by @snsf.ch in @pandeylab.bsky.social at @unibe.ch @dbmr-unibe.bsky.social @medfacultyunibe.bsky.social

Postdoctoral Research Position on modulation of human steroid and drug metabolism by redox proteins like P450 oxidoreductase (POR), Ferredoxin reductase (FDXR), ferredoxin (FDX1). funded by @snsf.ch in @pandeylab.bsky.social at @unibe.ch @dbmr-unibe.bsky.social @medfacultyunibe.bsky.social

PhD Student in Molecular and Translational Medicine: Dissecting & Targeting a Human Metabolic Disorder funded by @snsf.ch in @pandeylab.bsky.social @unibe.ch @medfacultyunibe.bsky.social @dbmr-unibe.bsky.social

📣 Check out the Program for 24th ICCP450 meeting 📣 lnkd.in/eei79-2y www.ICCP450Bern.Unibe.ch Leading experts in #P450 research from across the world are gathering in beautiful Bern from 30th June to 4th July 2025!!

24th ICCP450 meeting June to 4th July 2025 30 at @unibe.ch is being generously supported by a grant to @pandeylab.bsky.social by 🙏 @snsf.ch #SNSF #Switzerland. 🌍Join us in Bern. Register: iccp450bern.unibe.ch #Science #Heme #CytochromeP450 #P450

Latest paper in @springernature.com by Jibira Yakubu @pandeylab.bsky.social shows curcumin + piperine nanoparticles (CPN) inhibit steroid production in prostate cancer cells! #ProstateCancer #Nanomedicine #Curcumin Read: doi.org/10.1038/s415... @unibe.ch Funded by Cancer Research Switzerland

🐻 Get ready, #P450 peeps! for guru David (aka @p450nelson.bsky.social )! #ICCP450! 🎉 He literally wrote the book (well, the website!) on P450 nomenclature 🧬 – foundational work on drug metabolism, toxicology genomics! 🗓️ #P450 #CytochromeP450 #DrugMetabolism #Pharmacology 🔬 www.iccp450bern.unibe.ch

24th ICCP450 meeting @unibe.ch will have several spots for presentations by PhD Students and Postdoctoral Fellows. Opportunities to get travel support. #ICCP450 #Science #Conference #Switzerland #Bern #Pharmacology #Biochemistry #DrugDiscovery #Enzymes #Protein Info: www.ICCP450Bern.Unibe.ch

📢 Get ready to hear Prof. Steve Sligar at 24th #ICCP450 meeting in #Bern, #Switzerland! 🇨🇭🗓️ 🎉 🔬✨ Don't miss the chance to learn from a true leader in #cytochromeP450 ! ➡️ info: iccp450bern.unibe.ch See you in Bern! 👋 #DrugMetabolism #Biochemistry #Science #P450 🧪🧬

Exciting new publication! 🧪 Our latest research on "Pyridine indole hybrids as novel potent CYP17A1 inhibitors" in #prostatecancer #P450 is out now! Read more at www.tandfonline.com/doi/full/10.... #DrugDiscovery #MedicinalChemistry #CYP17A1 #Research #NewPublication

📢 Save the date! 24th International Conference of Cytochrome P450 (#ICCP450) is coming to Bern, Switzerland! 🇨🇭 organized by @pandeylab.bsky.social @unibe.ch lineup of leaders in drug metabolism Learn more www.iccp450bern.unibe.ch #P450 #Conferences #Bern #Switzerland #Science #Research #ICCP450Bern

New preprintalert! 🚨 We analyzed human growth hormone variants & found key residues for receptor binding & how mutations can cause growth disorders. 🧬🔬 #GrowthHormone #Research [https://doi.org/10.1101/2025.03.19.644177](doi.org/10.1101/2025...) #Science #MedTwitter #Endocrinology

New preprint alert! 🚨 @pandeylab.bsky.social analyzed human growth hormone variants & found how mutations can cause growth disorders. @unibe.ch #ESKAS 🧬🔬 #GrowthHormone #Research [https://doi.org/10.1101/2025.03.19.644177](doi.org/10.1101/2025...) #Science #MedTwitter #Endocrinology

Registration for 24th International Conference on Cytochrome P450 #ICCP450 is now open: www.iccp450bern.unibe.ch Conference is being organized by @pandeylab.bsky.social of @unibern.bsky.social Leading #P450 researchers from across the world will present their latest work at this meeting.