Richard Bayliss
@molecularrichard.bsky.social
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reposted by
Richard Bayliss
EMBO Reports
22 days ago
Jennifer A Miles,
molecularrichard.bsky.social
et al model the Aurora A-Bora-Plk1 ternary complex revealing how Bora bridges both kinases
#RefereedPreprint
@reviewcommons.org
link.springer.com/article/10.1...
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reposted by
Richard Bayliss
Stephen Royle
10 months ago
I wrote something about why giving negative feedback to your colleagues can be a bit like slaying vampires in The Lost Boys, or something like that.
quantixed.org/2025/04/23/f...
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Feedback Deficiency: the tricky art of effective peer feedback – quantixed
https://quantixed.org/2025/04/23/feedback-deficiency-the-tricky-art-of-effective-peer-feedback/
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A masterclass in molecular imaging - too exciting for (this former NPC-phile's) words!
add a skeleton here at some point
11 months ago
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First post on here to mark the lab's first paper of the year. It's a belter. The product of several collaborations, many techniques skilfully applied and incredible persistence. 1/n
doi.org/10.1083/jcb....
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Structural characterization and inhibition of the interaction between ch-TOG and TACC3 | Journal of Cell Biology | Rockefeller University Press
Shelford, Burgess, and colleagues present a structural model of the interaction between TACC3 and ch-TOG. They discover Affimers that can inhibit this inte
https://doi.org/10.1083/jcb.202407002
11 months ago
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reposted by
Richard Bayliss
Stephen Royle
11 months ago
AlphaFold was a game changer for this project. AF stories are a bit boring aren't they? It helped really us to make sense of our structural data. With some neat HDX-MS experiments, it all came together. A big thank you to all the authors, it's great to see it published! 3/n
doi.org/10.1083/jcb....
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Structural characterization and inhibition of the interaction between ch-TOG and TACC3 | Journal of Cell Biology | Rockefeller University Press
Shelford, Burgess, and colleagues present a structural model of the interaction between TACC3 and ch-TOG. They discover Affimers that can inhibit this inte
https://doi.org/10.1083/jcb.202407002
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