Ryan Vignogna
@rvig.bsky.social
📤 38
📥 30
📝 11
Postdoc
@fromme-lab.bsky.social
| Heja BVB
Mind the GAP 🚧🕳️🚧 Excited to share the latest preprint from the Fromme Lab (
@fromme-lab.bsky.social
), showing that the DENN domain protein Avl9 functions as an Arf-GAP, revising long-standing assumptions about DENN protein function, 🧵:
www.biorxiv.org/content/10.6...
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Avl9 defines a family of GTPase-activating proteins that regulate diverse cell biological functions
Ras-related GTPases are molecular switches regulating hundreds of signaling and trafficking pathways in cells. Many GTPase regulators remain to be identified despite extensive genetic and biochemical ...
https://www.biorxiv.org/content/10.64898/2026.01.05.697756v1
4 months ago
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reposted by
Ryan Vignogna
Fromme Lab
over 1 year ago
Excited to share the published version of our work by
@ryanfeathers.bsky.social
and
@rvig.bsky.social
on the structural basis for activation of Rab6 by the Ric1-Rgp1 complex!
rdcu.be/d2mu3
Here is an updated thread about the paper we first shared on that older platform when we posted the preprint
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