Caroline (Lindy) Rae
@brainmetabolism.bsky.social
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๐ฅ 154
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Neurochemist, MRI afficionado, she/her. Dedicated theobrominian
Super pleased to have finally published our latest neurochemistry review on the many and varied roles of aspartate in brain.
rdcu.be/eqMHd
4 months ago
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New paper showing a key component of the glutamate-glutamine cycle. NTT4 (SLC6A17) supplies Gln for the presynaptic production of Glu. Needed to sustain rapid ongoing excitatory synaptic transmission and has roles in memory formation and other behaviours.
doi.org/10.1016/j.pneurobio.2025.102785
4 months ago
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New review on glutathione and its role in astrocytes from lab of GSH guru Ralf Dringen.
doi.org/10.1111/jnc....
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Glutathione Metabolism of the BrainโThe Role of Astrocytes
Astrocytes supply neurons with the substrates for the synthesis of GSH (ฮณGluCysGly). Astrocytes provide neurons with precursors for the three amino acids that are needed for GSH synthesis. The supply....
https://doi.org/10.1111/jnc.70073
5 months ago
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reposted by
Caroline (Lindy) Rae
International Society for Neurochemistry
6 months ago
ISN is proud to support
#SONA2025
in Marrakech! ๐ด Join us for sessions with Rosa Cossart, Ines Elbini, Elisabeth Ngo Bum, and our ISN Lunch Talk. Visit the ISN booth to connect, learn more about the society, and grow in neurochemistry.
#WeAreNeurochemistry
#neuroskyence
#NeuroSky
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Fantastic @neurochemistry.org sponsored talk at Society of Neuroscientists in Africa from Rosa Cossart. Detecting a body size dependent developmental switch in the GABAergic hippocampus which is disrupted in an
#autism
model.
#SONA2025
6 months ago
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reposted by
Caroline (Lindy) Rae
Australian National Imaging Facility
6 months ago
New Nature Methods paper co-authored by experts from
@globalbioimaging.bsky.social
highlights the need for sustained investment in open, long-term image data storage. Read more:
doi.org/10.1038/s415...
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Enabling global image data sharing in the life sciences - Nature Methods
This Perspective provides a roadmap toward globally federated open data resources for bioimaging data.
https://doi.org/10.1038/s41592-024-02585-z
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reposted by
Caroline (Lindy) Rae
International Society for Neurochemistry
7 months ago
Job Opportunity at JNC!โ๏ธ The Journal of Neurochemistry is looking for a Freelance Editorial Assistant! If you have a background in science and publishing, this is your chance to join a global research community. โ Remote & flexible โ Support publishing โ Global network ๐Apply here:
bit.ly/3FAs1M6
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reposted by
Caroline (Lindy) Rae
International Society for Neurochemistry
8 months ago
๐ฐ ISN News Issue 3 is here! ๐ง ๐
@altmetric.com
scores - What do they measure? ๐ Rui Rodrigues(
@ruisrodrigues.bsky.social
) & Anna Hoffmann share insights on award -winning posters. ๐ What do p-values really tell us? ๐
ow.ly/NH5L50V3wgs
#WeAreNeurochemistry
#neuroskyence
#BrainResearch
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Happy to have helped (skyless) Alistair Carroll publish the first paper from his PhD research. Thereโs more to come!
add a skeleton here at some point
10 months ago
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reposted by
Caroline (Lindy) Rae
Paula Brunton ๐ด๓ ง๓ ข๓ ณ๓ ฃ๓ ด๓ ฟ
10 months ago
Interested in how maternal stress affects the offspringโs brain? Come and do a PhD with us in beautiful Edinburgh. More info here:
www.findaphd.com/phds/project...
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Interesting. Seems to need relatively high levels of R-BHB.
add a skeleton here at some point
10 months ago
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Time to (re)join for all neurochemists!๐๐๐๐๐๐
add a skeleton here at some point
10 months ago
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This is soo cool ๐ Awake fMRI in mice.
doi.org/10.1162/imag...
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Whole-brain responses to visual and auditory stimuli in anesthetized and minimally restrained awake mice using quiet zero echo time fMRI
Abstract. Functional MRI (fMRI) is a flexible tool for sensory perception studies in animal models. However, animal fMRI studies are generally performed under anesthesia. Unfortunately, anesthesia aff...
https://doi.org/10.1162/imag_a_00384
11 months ago
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Can verify that it is lovely. I gave one to an astrocyte aficionado but it was hard parting with itโฆ.
add a skeleton here at some point
11 months ago
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Just published a little paper about the role of L-Proline in brain metabolism. It stimulates mitochondrial metabolism but doesn't seem to do it by being metabolised (under the conditions studied). Yet another unsolved mystery in brain energy metabolism... Scratches head....
doi.org/10.1007/s110...
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l-Proline Alters Energy Metabolism in Brain Cortical Tissue Slices - Neurochemical Research
L-Proline (l-Pro) is a non-essential amino acid which, in high concentrations, can cause neurological problems including seizures, although the causative mechanism for this is unclear. Here, we studie...
https://doi.org/10.1007/s11064-024-04262-1
11 months ago
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Thanks for underlining this really important support initiative
@zilamartinezlozada.bsky.social
The ISN
www.neurochemistry.org
has support for carers sewn into its grant and travel schemes + special support for travel to the biennial meeting. Next one is in fantastic New York city in 2025.
add a skeleton here at some point
11 months ago
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Sodium dysregulation may play a role in Alzheimer's disease with links to increased amyloid-dependent tau pathology, neurodegeneration, and cognitive impairment. Sodium channel subunits (SCN2B &3B) showed strongest correlation with hippocampal volume and cognitive function
doi.org/10.1111/jnc....
11 months ago
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Latest issue of ISN News is out and available to read online. Includes advice on responding to reviewers from
@drbreaky.bsky.social
www.neurochemistry.org/isn-news-02/
11 months ago
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