Luis Daniel Cruz-Zaragoza (@luisdcruzz.bsky.social)

Albert and Mary Lasker Foundation 6 months ago

@luisdcruzz.bsky.social et al. introduce a method to silence mitochondrial mRNA translation in living human cells using peptide-morpholino chimeras, enabling analysis of mitochondrial gene expression and its integration into cell physiology. 🧪 www.science.org/doi/10.1126/...

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Silencing mitochondrial gene expression in living cells Mitochondria fulfill central functions in metabolism and energy supply. They express their own genome, which encodes key subunits of the oxidative phosphorylation system. However, central mechanisms u... https://www.science.org/doi/10.1126/science.adr3498