Happy to share the definitive version of our last paper about the role of TET enzymes and DNA demethylation in retinal development @clark-lab-retina.bsky.social journals.plos.org/plosbiology/...

Our work on the TET enzymes in retinal development is out. We identified that rod fate is inhibited when DNA demethylation is prevented by removal of the TET enzymes. Interestingly, photoreceptor numbers are normal. We utilized WGBS and bACE-seq to profile the precise localization of 5mC and 5hmC,…

Well, the Biology and Development of the Eye (BDE) study section has been postponed (previously scheduled for Thurs/Fri). I’m very disappointed on behalf of the applicants and reviewers, who all want this meeting to happen. I’m also grateful to the NIH staff who work so hard to make science happen.

First post on this platform is to announce that our preprint is posted to bioRxiv: bioRxiv 2025.02.03.636318; doi: doi.org/10.1101/2025...