First Patient In is important but treating it as a KPI (like the NHS’s 150-day target) risks gaming the metric - like congratulating a runner at the start line. What matters is making research part of care, with patients choosing it as a trusted pathway. 👉 aaronsopslog.wordpress.com/2025/09/26/f...

Getting clinical trials greenlit is harder than it should be. Contracts, IMP, radiation assurance… It's all very important. However, a major issue is study designs that forget what’s realistic for sites and for patients. I’ve shared a few ideas: aaronsopslog.wordpress.com/2025/09/19/g...

I got to speak today at UHDB’s International Patient Safety Day event on listening in safety. Systems need to make space for being a good listener but also a good “listenee.” As a Patient Safety Partner, I get to see when patients, families, and staff are all part of the conversation.

Site Initiation Visits shouldn’t just be box-ticking. My latest post: moving past slide decks, modular training, and turning SIVs into genuine conversations. 🔗 aaronsopslog.wordpress.com/2025/09/12/b...

Are we ready? Trial success depends on more than opening sites. First, there's site evaluation and feasibility = capacity, capability, and commitment. aaronsopslog.wordpress.com?p=110

A great legacy stemming from a tragic incident. Martha's Rule is in effect at all acute hospitals in England, giving patient's and their loved ones a better opportunity to be listened to. The pilot evidence shows a clear benefit to patient safety and outcomes. www.theguardian.com/society/2025...

Using a clinical trial protocol as the operational “source of truth”? Could it be time for an upgrade? aaronsopslog.wordpress.com/2025/08/29/b...

Ever had to manage change in a complex documents with more editors and suggestions than you can shake a stick at? aaronsopslog.wordpress.com?p=85

Radiopharmaceutical trial docs include the usual IMP paperwork, but with a twist - short half-lives + just-in-time delivery. No room for delays or errors. I pinned a few ideas for how we could make these workflows easier. Link: aaronsopslog.wordpress.com/2025/08/15/r...

The Schedule of Events in clinical trials is key but often a mess. I have been having a think and would also welcome your own thoughts on what works for you: aaronsopslog.wordpress.com?p=51

Always great to attend the @hralatest.bsky.social Study Setup Advisory Board and hear about the important work underway to streamline UK clinical trials. I was pleased to share updates on @spectre-ctops.bsky.social - great to see so much interest in our next steps! #ClinicalTrials #UKResearch

Perhaps my email signature is going to be too long for a bit but I'll be happy to have this addition for a time to reflect work of our #GreenImpact team at @ucl.ac.uk 's Institute of Clinical Trials and Methodology. Lovely team to have chaired!

Recently marked our 100th participant joining the STAMPEDE2 study for people with metastatic prostate cancer. A privilege to see patients sign up following hard work by @mrcctu.bsky.social colleagues, funders and, importantly, teams at all onboarded locations 👉 www.stampede2trial.org/sites/stampe...

Excited to be hosting our first workshop tomorrow, building on work from @mrcctu.bsky.social to improve clinical trial site setup processes. We’re joined by collaborators from CTUs and hospitals across the UK. Watch this space for updates!