"Large enough to lead, small enough to stay disciplined, we’ve spent a decade working with founders on everything from first hires to long-term strategy." ~ Managing Partner Julia Moore on how @breakout-ventures.bsky.social steps up to stand out. Read more: www.linkedin.com/pulse/issue-...

It's not every day that your portfolio company's CEO 𝒂𝒏𝒅 your firm's Managing Partner land a spot on @cnbc.com 🎉 Congrats to Harshal and the ZymoChem team, and thanks for inviting our very own Lindy to join you on screen!

It's not every day that your portfolio company's CEO 𝒂𝒏𝒅 your firm's Managing Partner land a spot on @cnbc.com 🎉 Congrats to Harshal and the ZymoChem team, and thanks for inviting our very own Lindy to join you on screen!

Want to know what it takes to launch a science-powered startup? Just ask the founders and advisors doing it! Thank you to everyone who joined our inaugural Founder Outpost & Campfire. In case you missed it... check out our Medium post for highlights! medium.com/breakoutvc/n...

When your PhD research 𝘭𝘪𝘵𝘦𝘳𝘢𝘭𝘭𝘺 fuels a clean tech revolution... Check out how Twelve's co-founder Etosha (Eee-tah-sha) Cave took her Stanford research out of the lab and into the world to scale tech that converts CO₂ into jet fuel. www.nature.com/articles/d41...

Congratulations to portfolio company Noetik on their new partnership with Agenus to predict patient outcomes for immuno-oncology treatments. A big step forward for personalized cancer immunotherapies! www.genengnews.com/topics/artif...

𝐁𝐚𝐝 𝐍𝐞𝐰𝐬: 80% of our clothing relies on fabrics made from petroleum. 𝐆𝐨𝐨𝐝 𝐍𝐞𝐰𝐬: Bio-based alternatives from companies like ZymoChem are on the horizon! www.voguebusiness.com/story/sustai...

Ammonia production accounts for ~1% of 𝐠𝐥𝐨𝐛𝐚𝐥 CO₂ emissions. Copernic Catalysts’ tech, developed in collaboration with Schrödinger, could cut that number by half 𝘢𝘯𝘥 create resilient supply chains. extrapolations.com/building-a-p...

What do you get when you combine robotics, AI, and implantable devices? With Phantom Neuro's tech, "You 𝘵𝘩𝘪𝘯𝘬 about closing your hand, and the robotic hand closes." Hear more from Phantom Neuro's CEO and Founder, Connor Glass, on the Austin4America stage www.youtube.com/watch?v=_tcd...

Congratulations to Chronic Migraine-defeating company ShiraTronics, Inc. for landing a top spot in The Tech Tribune's Best Tech Startups in Minnesota! thetechtribune.com/10-best-tech...

Nobody wants to choose between updating their wardrobe and protecting our planet. Scaling their biotech-powered materials, Modern Meadow leads the charge to meet consumers' sustainability demands. www.rinnovabili.net/business/fas...

Nature inspires aviation, from mechanics to aerodynamics. Breakout's portfolio company Twelve is taking this one step further with its "𝘪𝘯𝘥𝘶𝘴𝘵𝘳𝘪𝘢𝘭 𝘱𝘩𝘰𝘵𝘰𝘴𝘺𝘯𝘵𝘩𝘦𝘴𝘪𝘴" tech that turns CO₂ and water into jet fuel. And giants like United Airlines are jumping on board.

A new 5-year analysis of patients at Our Lady of the Lake Regional Medical Center found that 57% of septic patients identified by Cytovale's 8-minute test 𝘸𝘰𝘶𝘭𝘥𝘯’𝘵 have been flagged by traditional ICU-level triage. www.prnewswire.com/news-release...

Why do we use our socials to talk about our founders so much? It's pretty simple. We could describe how Breakout finds and supports early-stage companies building the future of science. We could use catchy adjectives like "founder-friendly" or "deeply experienced" Or... we could just show you.

How do you turn a 𝘱𝘦𝘵𝘢𝘣𝘺𝘵𝘦 of tumor data into a new cancer therapy? With a nimble team, enormous datasets, and some seriously powerful AI. Meet Breakout company Noetik, an AI-native biotech using machine learning to redefine how we understand and treat cancer.

Palm oil is everywhere, but what if we could keep the functionality without the deforestation and saturated fats? If your first thought is to create a GMO... we have a better idea. Say hello to the future of fermentation with Checkerspot. Read the AgFunder article: agfundernews.com/fats-from-fe...

What if the big breakthrough for sustainable diapers, leggings, and industrial chemicals was actually very, very small? Even... 𝒎𝒊𝒄𝒓𝒐𝒔𝒄𝒐𝒑𝒊𝒄? Tune into @synbiobeta.bsky.social's Built with Biology to hear how ZymoChem replaces petroleum-based materials with carbon-smart bioproducts made by microbes.

While most BCI tech starts at the brain, Phantom Neuro started at the 𝒑𝒓𝒐𝒃𝒍𝒆𝒎. With Ottobock leading the $19M Series A, we’re thrilled to double down on Phantom’s radically intuitive approach to mobility. Read why we (re)invested, by Breakout Ventures’ Dana Watt, PhD: medium.com/breakoutvc/p...

Phantom Neuro grabs $19M to help amputees gain control of their phantom limbs

Catch the latest SynbioBeta podcast episode: From Microbes to Materials: ZymoChem's Vision for a Plastic-Free Future Listen here: synbiobeta.com/listen/from-microbes-to-materials-zymochems-vision-for-a-plastic-free-future

Raising funding for your biotech startup? Join WIB-San Francisco Bay Area's "Navigating Funding & Investment" panel (and say hi to our Partner, Dana Watt!) to learn what it takes to attract capital in today’s landscape. Learn more and register here: community.womeninbio.org/event/sanfra...

Spinouts from the Institute for Protein Design, University of Washington—like A-Alpha Bio—have helped establish Seattle as a major life science hub. Learn how at the Life Science Innovation Northwest conference April 23-24: lifesciencewa.org/events/life-...

Thoughts in order after hearing this news as part of the team that invested early in ZymoChem: 1. Woah, sustainable nylon production would be huge for the planet. 2. What a big win for ZymoChem and biomaterials producers in general. 3. Please please please let this turn into lulu-x-Zymo swag

lululemon and ZymoChem are partnering to replace petroleum-based nylon—which makes up 31% of material in lululemon products, by weight—through the power of biotechnology! www.esgtoday.com/lululemon-pa...

Under the leadership of its new CEO, John Krzywicki, Checkerspot is doubling down on eco-friendly fats to create resilient supply chains and reduce reliance on unsustainable sources like palm and coconut oil. www.foodnavigator-usa.com/Article/2025...

Universities sit at the crossroads of groundbreaking innovation, charged with bridging the gap between research and commercialization. It's a big lift—but they don't have to do it alone! Attending next week's AUTM Annual Meeting? Say hi to our Director of Platform, @susannalharris.bsky.social!

The path to get medicines from discovery to commercialization is notoriously long and difficult—and it could get even harder with federal funding cuts. Will our industry rise to the challenge? Thank you to @gwendolynawu.bsky.social for diving into the topic! www.biopharmadive.com/news/biotech...

Congratulations to EnPlusOne Biosciences on securing $10M in new financing to continue scaling their RNA synthesis platform! This tech will be 𝒄𝒓𝒖𝒄𝒊𝒂𝒍 to meet rising demands for RNA therapeutics. www.businesswire.com/news/home/20...

You've heard about Brain-Computer Interfaces (BCI) for humans... but what about 𝐁𝐂𝐈 𝐟𝐨𝐫 𝐝𝐨𝐠𝐬? (Hang on - we promise it will make scents) Learn how Canaery's "nose-computer interface" interprets what a dog is smelling in real time. www.wired.com/story/nose-c... @wired.com @emilymullin.bsky.social

Seeing big upsides to turning CO₂ into valuable resources, Amazon’s Climate Pledge Fund has joined the push to back Twelve—a major step for decarbonizing industries like aviation, shipping, and manufacturing. esgnews.com/amazons-clim...

The ✨cool factor✨ of Brain-Computer Interfaces is undeniable—as is their potential for restoring mobility and improving lives. 𝘉𝘶𝘵 𝘢𝘳𝘦 𝘸𝘦 𝘮𝘢𝘬𝘪𝘯𝘨 𝘵𝘩𝘦 𝘱𝘳𝘰𝘣𝘭𝘦𝘮 𝘩𝘢𝘳𝘥𝘦𝘳 𝘵𝘩𝘢𝘯 𝘪𝘵 𝘯𝘦𝘦𝘥𝘴 𝘵𝘰 𝘣𝘦? When it comes to biotechnology, real-world impact >>> hype. www.youtube.com/watch?v=veZJ...

What if we could stop with the trial-and-error approach to developing cancer immunotherapies and actually 𝘱𝘳𝘦𝘥𝘪𝘤𝘵 which drugs will work for patients in the first place? Hear NOETIK's CEO, Ron Alfa, explains how computation uncovers hidden patterns in patient data: pixelscientia.com/podcast/harn...

Shoutout to our very own Nima Ronaghi, PhD for being highlighted in Deep Checks' Featured Fund Partner section! As a Principal at Breakout Ventures, Nima finds and supports companies pushing the boundaries of building with science. 𝐑𝐞𝐚𝐝 𝐦𝐨𝐫𝐞 𝐨𝐧 𝐃𝐞𝐞𝐩 𝐂𝐡𝐞𝐜𝐤𝐬: www.deepchecks.vc#:~:text=FEAT...

LPs want more than just healthy returns – they want to know 𝒉𝒐𝒘 firms get those returns. From understanding strategy to keeping an eye on valuation decisions, transparency is key. Breakout's Julia Moore takes the stage next week at the With Intelligence Summit to share insider tips.

Thank you to our cohosts Dolby Family Ventures and AIX Ventures for helping us fill the historic Redwood Room with founders, investors, and partners leading the way in frontier platforms. Here's a thread of our favorite photos from the evening. DM us if you attended and want access to the gallery.

Heading to the Cleantech Forum meeting next week? Be sure to catch ZymoChem's CEO and Co-Founder, Harshal Chokhawala, at the "Ones to Watch" innovation showcase! Register today for the meeting in San Diego on January 27th-29th: www.cleantech.com/event/cleant...

What if cutting-edge medicines for obesity, diabetes, and even cancer could be administered 𝒘𝒊𝒕𝒉𝒐𝒖𝒕 𝒊𝒏𝒋𝒆𝒄𝒕𝒊𝒐𝒏𝒔? ARPA-H awarded $41M to a team of scientists and innovators who are making this dream a reality. News at a glance in the thread. www.engineering.columbia.edu/about/news/t...

In just one year of its commercialization, Cytovale's sepsis diagnostic technology has been adopted by two health systems across three states and has 𝐡𝐞𝐥𝐩𝐞𝐝 𝐨𝐯𝐞𝐫 𝐟𝐢𝐟𝐭𝐞𝐞𝐧 𝒕𝒉𝒐𝒖𝒔𝒂𝒏𝒅 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬. www.prnewswire.com/news-release...

With landmark regulations taking effect around the world in 2025, the $300bn textiles market is facing its most transformative year yet. Sustainable, bio-based materials from companies like Modern Meadow are not just innovative—they're 𝒆𝒔𝒔𝒆𝒏𝒕𝒊𝒂𝒍. www.fibre2fashion.com/industry-art...

The first MPS I patient treated with Immusoft's engineered B cell therapy saw 𝐢𝐧𝐜𝐫𝐞𝐚𝐬𝐞𝐝 𝐦𝐨𝐛𝐢𝐥𝐢𝐭𝐲, 𝐫𝐞𝐝𝐮𝐜𝐞𝐝 𝐩𝐚𝐢𝐧, & 𝐛𝐞𝐭𝐭𝐞𝐫 𝐪𝐮𝐚𝐥𝐢𝐭𝐲 𝐨𝐟 𝐥𝐢𝐟𝐞. CEO Sean Ainsworth explains why this treatment wins out on this week's #RARECast podcast from Global Genes. globalgenes.org/raredaily/en...

With the launch of their OCTO-VirtualCell (OCTO-vc) and Celleporter visualization tool, NOETIK is taking the world a (𝒃𝒊𝒈) step forward in how we understand and interact with biological systems.

Up to 98% accuracy across hand 11 gestures at near-natural latency levels… with only 10 minutes of calibration. To quote a study participant, Phantom Neuro’s muscle-machine tech is “going to be a total game changer.” Read the full article from Wired www.wired.com/story/ampute...

Congratulations to our friends at Dimension on today's big announcement! Exciting news for everyone building at the intersection of science and technology. techcrunch.com/2024/12/09/d...

The best "problem" a VC media manager can have is when the portfolio companies have too much good news. Cheers to Cytovale for a very big week: from speaking at Forbes' Healthcare Summit, to expanding into yet another hospital, to being named in Inc. Magazine's Best in Business. Links below!

People with Chronic Migraine experience 15 headache days 𝘦𝘷𝘦𝘳𝘺 𝘮𝘰𝘯𝘵𝘩. With an FDA-approved pivotal trial officially launched, ShiraTronics' neuromodulation therapy could be the answer millions of patients have been searching for. www.massdevice.com/shiratronics...

When biotech meets nanotech, the possibilities are endless... and 𝐬𝐮𝐬𝐭𝐚𝐢𝐧𝐚𝐛𝐥𝐞. Need proof? Check out the new All Rounder Bio-X Gloves that blend plant-based leather from Modern Meadow's (a Breakout portfolio company) with Graphene-X's graphene-integrated fabric. www.graphene-x.com/products/all...

After attending Magnify in 2022 and 2023 as a community member, I can still hardly believe that I got to help put on this year's event as part of the Breakout Ventures team <3

In this season of gratitude, we are most thankful for... 𝐲𝐨𝐮! We're inspired by this community of founders, investors and co-conspirators who are building a future powered by science. Thank you to everyone who made this year's Magnify such a success. Check out the photos⬇️ medium.com/breakoutvc/a...

In this season of gratitude, we are most thankful for... 𝐲𝐨𝐮! We're inspired by this community of founders, investors and co-conspirators who are building a future powered by science. Thank you to everyone who made this year's Magnify such a success. Check out the photos⬇️ medium.com/breakoutvc/a...

Visionary entrepreneurs don't accept the status quo. The 10 years and $1B+ it takes to bring medicines from discovery to approval is unacceptable... and ready for a tech overhaul. Thanks to everyone who joined our Magnify Debate to decide: how will computation reshape the drug development funnel?