Looking forward to presenting this on Wed 17 Sept uchealth.zoom.us/webinar/regi...

Fine, but that seaweed might whiff a bit....

Wow!

But gruniad website still free for now

ACS Washington presentation lnkd.in/dxvaQn9V A well attended joint CHAL & CINF session and thanks to Emilia Hietala and Collaborative Drug Discovery - CDD Vault

Nice to see a steady engagement increase for my blog lnkd.in/ebDNdfG :)

Pleased to attend American Chemical Society Washington next week with ACS CINF slots for "Update of InChIKey searching in Google" Aug 18 from 3:20 PM and "Mining the outputs of AI drug discovery from patents" August 21 9:05 (a CDD Vault collaboration)

Good idea mate...

Enjoyable break visiting my friend and leading Mosel Winemaker Franz-Peter Schmitz from Römerhof in Riol. Great to catch up on the wine technology, commerce and biochemistry as well as socially. New post pending as a follow on from a past blog cdsouthan.blogspot.com/2013/06/wine...

Couple of recent posts at cdsouthan.blogspot.com

Real shame 2c @acs.org capitulate to the MJB (mumbo jumbo brigade)

Good 2c a steady < over the last year but more engagement always welcome :) cdsouthan.blogspot.com

Refreshing Midsummer's day swim at Naset. Finally warm enough to get to second jetty when it was so cold last month I could only just make the first. We'll see how many weeks it takes to extend my efforts to the third jetty (red on right) and eventually ~550 m to get across the inlet (lower left)

Last day so please do the same (see LinkedIN posts from me and others for the link)

Broken DOI :(

Brocken/very slow link?

A targeted effort to find and isolate some of the most harmful papers from the medical literature:

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

This was impressive :)

Will PDB be impacted? :(

Important survey very relevant to my own and @cindycrowninshield.bsky.social followers so please fill in and ping out

Webinar: My Federal Grant was Terminated: What to Do Now? 📅 May 8, 2025 | 🕒 3 PM ET Registration required: us06web.zoom.us/webinar/regi...

I could say the same about drawing out 100s of glass pippete tips during my Masters in Virology - but I wont :)

Mayday holiday stroll yesterday appreciating the emphatic arrival of spring here in Naset

Bit of self-doubt by DECIMER and no exact match in PubChem but looks like it whacks the right BMS patent "Pyridinyl substituted oxoisoindoline compounds" pubchem.ncbi.nlm.nih.gov/patent/WO-20...

Good 2C and now in @gtopdb.bsky.social curation que but odd that AVI-4773 C#CCN1C(=C(C(=O)N(C2=CN=CC3=C2C=CC=C3)C1=O)N4C5=C(C=CC=C5)N=N4)N is an orphan in PubChem sans patent hits

But spanner in the works?

Thoughts on Demis Hassabis of Google DeepMind saying that AI could cure disease in general in ten years. Bonus index to my longer posts on AI/computational drug discovery over nearly 20 years!

Amen :)

aside: a stunning comment from David Baker, UW professor who won the Nobel Prize in 2024. Now 15 lab members are looking for positions overseas. “There’s so many amazing people who want to come in, & we can’t take them. The Nobel Prize was just a little blip. But things have gotten quite bleak.”

Quiet start to the year for the #greatcompoundrace with only Reaxys forging ahead. Puzzling small drop in PubChem patent chemistry looks like a Google Patents refresh.

I would guess that Novartis, Dupont, BASF, and Elsevier should be rather upset that they are listed (with their logos) as corporate sponsors. . .

As you may know @jpoverington.bsky.social I am a fan of bioinfogp.cnb.csic.es/tools/venny/... fan, although limited to 4 sets of normalised strings viz

Good 2c the excellent Ian Lloyd Pharma projects annual (free :) epistle on drug discovery stats. Will be avidly perused by @gtopdb.bsky.social IUPHAR. A glimmer of clinical phase acceleration, possibly with AI impact? #glashalffull

Essential reading jcheminf.biomedcentral.com/articles/10....

Gosh - X down, couldn't happen to a nicer site (irony)

It doesn't really go green here in West Sweden until well into April but it was nice to see this early sign of spring

Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4

While I hope they can fix it my Edinburgh University email @exseed.ed.ac.uk has not been forwarding properly for months so use my gmail for now

I’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War. Same link, new title and some updates.

Could do with some more traction on this; you know what to do :)

Technically this @rsc.org stuff should only be on LI, but here it is anyway :)

Great 2 c this @bindingdb.bsky.social webinar recording (link on homepage) from Michael Gilson including useful Q&A and yours truly even gets a micro Warhol unit in the SAB intro slide :)

Lots to dig into on this blogpost as a follow-on expansion from last year's The IUPHAR/BPS Guide to Pharmacology poster for British Pharmacological Society 2024 lnkd.in/dAbt-vdm (re-pings appreciated)

"Was" the envy of... :(

So what happened to that Craig Venter effort at more or less the same thing?