Mehle Lab
@mehlelab.bsky.social
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Our small bit about flu (mostly cool stuff by lab members). mehlelab.com
🧵 Thread on our new
@natcomms.nature.com
paper: TLDR -- ADP-ribosylation inhibits viral replication and represents a previously under-appreciated arm of innate immunity during flu infection. Read along for the details…. (1/11)
www.nature.com/articles/s41...
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Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection - Nature Communications
Influenza A virus infection causes a dramatic upregulation of ADP-ribosylation that as part of the cellular antiviral response, a process that is counteracted by the viral NS1 protein.
https://www.nature.com/articles/s41467-025-66136-6
7 days ago
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Let's try this Bluesky for a spin -- 🚨preprint thread 🚨 1/9
www.biorxiv.org/content/10.1...
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Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
https://www.biorxiv.org/content/10.1101/2023.12.12.570638v1
about 2 years ago
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