Please join us for Acne Global Education day on June 7th. We have an all-star cast lined up and it is going to be an outstanding session on everything acne. For more and to register: www.global-dermatology.com/en/events/ac...

Some more evidence from a meta-analysis of 6 RCTs to support that subdermal implants (i.e. Nexplanon) are more likely to cause acne than hormonal IUDs (OR 2.21). Something to keep in mind for those concerned about acne who otherwise don't have strong preferences. pubmed.ncbi.nlm.nih.gov/40069520/

🚨 News Alert 🚨 The FDA just released an important update regarding benzene in benzoyl peroxide products (www.fda.gov/drugs/drug-s...). See below for my thoughts and products to avoid:

A new report on the potential relationship between benzene and benzoyl peroxide was just released in @theJIDJournal. While I applaud continued efforts to address this important topic, I have some serious concerns with this study. 1/8 www.sciencedirect.com/science/arti...

There is growing interest in the role of home LED therapy for acne. In this systematic review and meta-analysis in JAMA Derm, we examine the evidence base for this treatment (TL/DR: it appears to have reasonable efficacy for mild acne): www.massgeneralbrigham.org/en/about/new...

While we often worry about SJS/TEN with TMP-SMX, it also can be associated with severe acute respiratory failure, particularly among younger individuals. Another reason to be very cautious about using it for acne: pubmed.ncbi.nlm.nih.gov/40012193/

Sherry Ershadi, an amazing research fellow in our lab this year, has put together these incredible acne/rosacea patient handouts. Feel free to use them if you find them helpful: barbierilab.bwh.harvard.edu/educational-...

Lately, we've seen a lot of discussion about the potential risk of benzoyl peroxide products breaking down into benzene. In this letter, we discuss some of the limitations with respect to the methodology and framing of the recent Kucera et al. article in the JID: www.jidonline.org/article/S002...

Minocycline-MR 40mg was recently FDA approved for rosacea. In this video, I will review the clinical trial data and share my thoughts on where it fits among our existing treatment options: #rosacea #minocycline #emrosi youtu.be/103ncqVznGk

Just out in BJD, interesting MR study lending further support to the potential role of Omega-3 being helpful in acne. These findings align with small trials and observational studies suggesting Omega-3 may be useful. 1/2 pubmed.ncbi.nlm.nih.gov/39936505/

Excited to share work with @labmuffin.com, Courtney Rubin, and James Pham, identifying how formulation characteristics might be associated with benzene levels in benzoyl peroxide products. Some helpful hypotheses to guide future product development. jamanetwork.com/journals/jam...

In this latest video, I review common reasons why isotretinoin is not working and how to address these clinical scenarios: youtu.be/gEc2qxdEH6Q

We often consider GoodRx to reduce out-of-pocket costs. In this @JAADjournals study, we find that @costplusdrugs frequently has lower prices for derm drugs (and the mail order aspect may be more convenient). Another good option to help with affordability. pubmed.ncbi.nlm.nih.gov/39863169/

Just out in @JAMADerm, we describe the psychometric properties of the 1-item ACORN Patient Global Assessment, which correlates well with the CASS IGA and also is highly responsive to change. This can be particularly useful for online surveys/assessments. jamanetwork.com/journals/jam...

Should we start with spironolactone or doxycycline for women with acne? Check out my breakdown of the FASCE trial here: youtu.be/zRbPfSCn9Ow

Just out in JAMA Dermatology, led by Jenny Lai, we evaluate long-term clearance outcomes among those treated with isotretinoin for acne. A thread: ⬇️ jamanetwork.com/journals/jam...

Do we really need to check frequent labs for isotretinoin? In this video, I go through the evidence about why we likely aren't getting much value from our current approach and even make a case for no monitoring: youtu.be/UpsW1iN9FRw

Some of the best evidenced-based info on acne treatment right here! @drjohnbarbieri.bsky.social #DRESSsyndrome #acnetreatment

Want to learn more about which are the best oral antibiotics for the treatment of acne, including the relative role of doxycycline, minocycline, sarecycline (Seysara), trimethoprim-sulfamethoxazole (Bactrim), amoxicillin, and azithromycin, among others? Check out this video: youtu.be/RgMXi92UjnQ

Catch up on some of the biggest topics, studies, and new medications for acne in my latest year-in-review video: youtu.be/vxqxzDYGSsg

In JAAD, we find evidence that acne may be a risk factor for fractures. This aligns with evidence that acne is associated with low vitamin D levels or might be related to pleiotropy or systemic inflammation www.sciencedirect.com/science/arti...

Nice article in @nytimes.com covering some of the recent benzene concerns (including benzoyl peroxide) as well as our recent work on this topic. www.nytimes.com/2024/12/05/w...

Isotretinoin can be highly effective for #acne and is the only prescription treatment that can provide a lasting remission. While we often discuss skin dryness, we don’t often consider the eyes. In this thread, let's explore the effects of #isotretinoin on the eye. #dermsky 1/9

Pityrosporum folliculitis ("fungal acne") can be easy to miss and needs different treatments than run of the mill acne. In this video, I go over what to look for and how to treat this condition: www.youtube.com/watch?v=n0YH...

Real world data shows no correlation between benzoyl peroxide use and benzene blood levels, or leukaemia/lymphoma/internal malignancies 👇🏻

Great breakdown by @labmuffin.bsky.social on the recent JID paper from Valisure evaluating benzene in benzoyl peroxide products. Stay tuned for more to come (we have a couple papers in the works): labmuffin.com/is-benzene-i...

While isotretinoin can be a great acne treatment for the right person, side effects can often be a challenge. In this video, I discuss how to avoid prevent some of the main side effects of isotretinoin such as dryness: youtu.be/KU3NsjdA50o

The SD-ACNE trial is a study comparing doxycycline versus spironolactone for women ages 16-40, and is currently enrolling in AR, FL, MA, NY, OH, OR, PA, TX, and VA. To learn more, visit: clinicalresearch.pennmedicine.org/us/en/listin...

We have another member of the original dermtwitter crew here! @drjohnbarbieri.bsky.social. Follow him for his excellent acne knowledge!

Is acne not improving? Make sure that it isn't due to one of these acne mimickers and learn how to treat them: youtu.be/6pXh_f6t3NE