Fariñas Lab (@farinaslab.bsky.social)

🧵 We’re excited to launch our lab’s Bluesky account with this new publication in Molecular Neurodegeneration! 🎉📢 We investigated how microglia respond to toxic α-synuclein (αSyn) in Parkinson’s disease (PD) and how aging changes this process. Here are the key findings 👇

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Age-dependent progression from clearance to vulnerability in the early response of periventricular microglia to α-synuclein toxic species - Molecular Neurodegeneration Cytoplasmic alpha-synuclein (αSyn) aggregates are a typical feature of Parkinson’s disease (PD). Extracellular insoluble αSyn can induce pathology in healthy neurons suggesting that PD neurodegenerati... https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-025-00816-1