Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Our paper 'Limits of message passing for node classification: How class-bottlenecks restrict signal-to-noise ratio' is now out as a preprint on Arxiv: arxiv.org/abs/2508.17822. 1/8

🚀 AI in Science Fellowships – Applications Now Open! The I-X Centre for AI in Science is recruiting up to 19 fellows to join their prestigious programme and accelerate artificial intelligence research in Engineering, Natural and Mathematical Sciences. 1/5

🚨 Opening in mid-July: 🔹 Up to 8x 2-year Independent Fellowships in AI in Science, supported by @schmidtsciences.bsky.social 🔹 Up to 2x 2-year Joint Fellowships with ICR & CNRS 🔹 Up to 3x 1-year Linked Fellowships at Imperial (followed by a 1 year linked fellowship at AIMS and NCBS). 2/2

🚨 AI in Science Fellowship Opportunities 🚨 🔹Now open: Up to 6x 4-year Independent Fellowships dedicated to AI in Science in a program supported by Schmidt Sciences and Imperial College London [@imperialcollegeldn.bsky.social]. 🔗 Find out more and apply: www.imperial.ac.uk/research-and... 1/2

An approachable interview published today www.imperial.ac.uk/news/264393/... about this paper www.nature.com/articles/s41...

We're pleased our exciting paper 'Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species' is now out in Nature Comms: www.nature.com/articles/s41...

Merry Cristae! Thanks to Hetvi for the art: @vuisnotabot.bsky.social

Systems and signals group in Imperial maths led by Nick Jones. Stay tuned for our latest research on #mitochondria #aging #genetics #biomathematics #physicalbiology #networks and #ML. We blog at systems-signals.blogspot.com and there's more about us here profiles.imperial.ac.uk/nick.jones/a...