Abandoning the Quadrupole with PAMAF™ That’s not the full story. SLIM + PAMAF shifts LC-MS performance from duty cycle to ion utilization, enabling 100× signal gains and >1000 Hz speeds on a QTOF. Read more: www.genomeweb.com/proteomics-p... #Proteomics #PAMAF

Sometimes what looks like one peak… isn’t. Co-eluting compounds make it hard to tell what you’re seeing, impacting confidence. At Los Alamos, Austin Anderson’s team is evaluating MOBIE® to add a second separation dimension and resolve LC overlaps. #Trailblazers2026

A birds eye perspective on the company proposing quadrupole-free proteomics. Additionally, see which vendors are suggested to most benefit from Mobilion's IMS approach www.genomeweb.com/proteomics-p...

The MOBILion team stepped out of the lab and into the kitchen, volunteering at Ronald McDonald House to prepare meals for families whose children are receiving medical care. Grateful to support an organization that provides comfort and community when families need it most.

Two-dimensional separations solve problems 1D methods can’t. A new study from Oliver Schmitz’s lab adds multidimensionality at the ion source with rapidly switchable ESI + plasma ionization, paired with HRIM from MOBILion on an Agilent QTOF. Read: pubs.acs.org/doi/pdf/10.1...

Behind every high-resolution measurement is the need to turn complex data into meaningful insight. As an Informatics Scientist at MOBILion, Lauren Royer Dissinger ensures ion mobility data is reproducible, high-quality, and actionable for researchers. #Trailblazers2026

Some of the hardest challenges in proteomics and metabolomics appear after measurement. As Gary Patti noted, faster workflows often trade certainty for speed. Adding another separation dimension is helping labs gain confidence without added complexity. #Trailblazers2026

The metallome is one of my favorite omes. Can’t wait until it’s front and center!

“This complexity calls for an additional dimension of separation beyond chromatography.” Genentech demonstrates HRIM resolving PS diastereomers across therapeutic oligos, turning a trial-and-error challenge into a predictable analytical strategy. pubs.acs.org/doi/10.1021/...

“What would you tell a girl who thinks science isn’t for her?” For International Women & Girls in Science Day, we asked the women of MOBILion to share their thoughts. One message stood out: there’s more than one way to belong in science. What would you say? 👇 #WomenInSTEM

Using ion mobility has often meant trading breadth for focus. For Christopher Chouinard, high-resolution ion mobility changed that, enabling wide, untargeted separations that deliver clearer identification in complex, real-world samples. #Trailblazers2026

Our CTO Daniel DeBord is heading to US HUPO 2026 with 3 presentations you won’t want to miss: ⚡ Lightning Talk + Poster: Waste Not, Want Not (single-cell proteomics) 🧬 Poster: From Blind Spots to Breakthroughs (PTM analysis) Connect with Daniel or Mick Greer while you’re there. #Trailblazers2026

MS2 speed limits proteome depth and completeness. When acquisition is slow, many peptides never get fragmented, driving undersampling and missing values. SLIM separates precursors in time to enable >500 Hz MS2 with high ion utilization. www.biorxiv.org/content/10.1...

Big congratulations to our CEO, Melissa Sherman, Ph.D., on being named a 2026 Women of Precision Medicine Honoree by DeciBio Consulting. Proud to see her recognized among leaders shaping the future of precision medicine. www.decibio.com/insights/wom...

MOBILion Systems' CTO Daniel DeBord will be presenting at the Gordon Research Conference: "Mass Confusion? High Resolution Ion Mobility Brings Clarity to Ion Fragmentation Analysis” 📅 Feb 25 | 🕚 11:50 AM – 12:20 PM #Trailblazers2026

For years, ion mobility meant tradeoffs: accuracy vs speed. Tim Causon found @mobilionsystems.bsky.social HRIM delivered stable, reliable data in routine use, repeatable CCS, aligned fragments, and separations that distinguish close compounds without slowing LC. A clearer standard. #Trailblazers2026

Progress in pharma doesn’t usually come from a single breakthrough. It happens steadily over time, with each step bringing greater clarity. In Pharma’s Almanac, @mobilionceo.bsky.social Melissa Sherman reflects on key advances. 🔗 pharmasalmanac.com/articles/looking-back-over-the-last-30-years

For years, lipidomics faced trade-offs: depth or throughput, accuracy or reproducibility. That constraint no longer holds. A new study shows HRIM delivers ~0.1% interlaboratory CCS precision while enabling deep triglyceride characterization, turning “or” into “and.” pubs.acs.org/doi/10.1021/...

Trailblazers aren’t defined by titles or timelines. They’re defined by the courage to do things differently, questioning assumptions, pushing limits, and moving forward when others say “this is how it’s always been done.” This is where it begins. #Trailblazers2026 #ScientificInnovation

As 2025 wraps, we’re grateful for a year of curiosity, collaboration & breakthroughs with our scientists, partners & customers. We look forward to the new challenges, milestones & discoveries that lie ahead in the new year. Warmest wishes from all of us at MOBILion Systems.

"We've always done it that way" costs drug developers time, money and potentially better therapies for patients. Listen to our podcast feature to hear us explain how traditional LC-MS workflows create blind spots, missing PTMs and slowing drug development: deeptechdigest.com/biotech/base...

Chimeric MS2, <1% ion utilization, 90% signal loss, workarounds dressed up as innovation. All problems that trace back to one thing: the quadrupole. Maybe it's time to stop believing it's all we have. analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.... #IonMobility #itSLIM @asms.org

It’s a great idea - what if IMS was as selective as a quadrupole?

Happy Thanksgiving from all of us at @mobilionsystems.bsky.social. This year we reached new milestones by pushing boundaries with our customers, partners & team. Thank you for being part of our journey. Wishing you a wonderful holiday with your loved ones.

Nikolai Slavov and Daniel DeBord and share how HRIM is transforming proteomics and beyond in The Analytical Scientist. Read how SLIM and other ion mobility platforms are redefining what’s possible: theanalyticalscientist.com/issues/2025/... #Proteomics

I'm developing my belief that physical and temporal separation is reaching its maximum potential for complexity. My research track of dealing with complex carbohydrates is working around separation limitations, starting from data feature engineering.

Still wrestling with sample complexity and poor resolution in your analyses? Our new study shows how ultrahigh resolution ion mobility could streamline biomarker/drug separations. Full paper published in JASMS: pubs.acs.org/doi/10.1021/... #IonMobility #MassSpec #Bioanalytics #SLIM @asms.org

The 24th HUPO World Congress is next week in Toronto, Canada. Make sure to add our poster session on how ‘PAMAF Analysis Enables 1,000 Hz Speeds with 100% Ion Utilization for Fast and Sensitive Discovery Workflows’ to your agenda. See you on Tuesday Nov 11, at 1:15pm. #PAMAF #Proteomics #HUPO2025

New paper from Clemson University shows how our low mass optimized platform delivers faster, more accurate steroid analysis for challenging low-mass isomers. Read it in JASMS here: pubs.acs.org/doi/10.1021/... #MOBIE #IonMobility #Steroidomics #MassSpec

Exciting news! Dr. James Dodds (UNC) will present his year-long work with the #MOBIE system at the upcoming Southeastern and Southwest joint regional meeting of the American Chemical Society. Join his session: 📅Mon, Oct 27 | 🕐1:30 PM | 📍Nautilus A @acs.org

If there was a certain vendor developing a brand new ion mobility instrument and is in the process of choosing a file format, this is timed incredibly well for them to catch the wave.

Exploring the dark multi-ome is a crucial step for #genomics, #metabolomics, and #proteomics. Our new article in @lcgcinternational.bsky.social discusses how new IM-MS tech like SLIM can solve big analytical challenges such as isomeric ambiguity and more: chromatographyonline.com/view/illumin...

Enantiomer separation is essential for safe drug development. Researchers at Vanderbilt Uni found #HRIM with copper–amino acid complexation on the MOBILion Platform enables true #chiral resolution & #enantiomeric excess quantification. Find out more here: www.mobilionsystems.com/resources/re...

New paper from Clemson University shows how rounded-turn #SLIM ion mobility system delivers faster, sharper steroid analysis, even for challenging low-mass isomers. Read it in JASMS here: pubs.acs.org/doi/10.1021/... #MOBIE #IonMobility #Steroidomics #MassSpec

Every time I cite CDC data in a report, manuscript, or general conversation I have a twinge of concern about how long I’ll be able to do that with confidence. Unless something changes. Or let’s be honest, someone.

Or, they could stay. Stand up for what they believe. Try and use what visibility they have to help stop injustices. But I guess running away so they can enjoy without discomfort is something to be applauded as brave?

Glad to see it! The blue states are stepping up where the federal government has failed us.

We need an HHS Secretary who respects science and does not make policy based on conspiracy theories. Vaccines are safe and effective. Kennedy is threatening the health of our kids and all Americans. He must resign.

Revealing new lipid diversity & structural insights are critical for discovering new diagnostic biomarkers. Read our new Quick Note summarizing research by @vanderbiltusac.bsky.social using high resolution ion mobility: view-su2.highspot.com/viewer/9311a... #MOBIE #IonMobility #HRIM #Lipids

Next week we’re attending the first analytica USA in Columbus! Don’t miss our posters and these Sept 11 oral sessions: ▪️Daniel DeBord — HRIM for complex proteomics (11:30–12) ▪️Oliver Schmitz — Exploring coupling Ion Mobility MS and comprehensive 2D-LC (12:30–1)

Analytica is coming to the US! 🎉 Sept 10–12 in Columbus, OH. Our CTO Daniel DeBord & SVP Frederick Strathmann will share insights on proteomics, exposomics & PAMAF. Register to join us here: analytica-us.com/en/ #proteomics #PAMAF #AnalyticaUSA

Many MS tools miss big chunks of data but BILLIE™ reveals what others leave unseen, driving deeper protein coverage, faster results, and better insights from even small samples. Proud to be named a Top 5 MS release of 2025 by @biotechniques.bsky.social: www.biotechniques.com/technology-n...

"What can I say? CJ's got hooks. That stuff just gets in your head."

Faster drug development starts with better protein characterization. Our PAMAF workflow delivers full sequence coverage + PTM ID in 20 minutes – no compromises needed. Better medicines for improved outcomes. Sign up for BILLIE updates here: go.mobilionsystems.com/BILLIEverVIP #biopharma

Pretty impressive results. One has to wonder which, internally, is more advanced and ready to be put on an commercially available instrument. Thermo's in-development IMS or Mobilion's SLIM? If it's the latter, maybe there will be an acquisition.

Spaces are filling up fast for our ASMS breakfast seminars! On Monday June 2nd, we will be joined by Dr. Sarah Choyke from Eurofins Specialty Services for a presentation on driving Advanced #PFAS analysis. Register here: go.mobilionsystems.com/ASMS2025_Bre... #ASMS2025 #MOBIE

Ready to go backstage with BILLIE? Join the exclusive MOBILion #BILLIE VIP Club and become a true #BILLIEver. Get front-row access to sneak peeks, early updates, and behind-the-scenes intel before #ASMS2025! Sign up below: go.mobilionsystems.com/BILLIEverVIP #Proteomics #PAMAF #MassSpec

Mark Strynar of the EPA highlights the value of non-targeted analysis in environmental monitoring to detect unknown chemicals missed by traditional methods. Technologies like our MOBIE system provide more confidence for identifications. Learn more: www.sciencedirect.com/science/arti...

Low load is where we shine even more with #PAMAF from @mobilionsystems.bsky.social.