What a week at #ASMS2026! Thank you to everyone who visited our booth, attended a seminar, stopped by a poster, or joined us at an event. Special thanks to Miriam Fico, Lauren Royer Dissinger, Leonard Rorrer, Mick Greer, Liulin Deng, and Daniel DeBord for sharing their work!

One of our favorite parts of #ASMS2026 was connecting with the community after hours. From our Speakeasy Night with live jazz, cocktails, a photo booth & vintage typewriter to Trivia and Game Night, thank you to everyone who joined us, and congrats to our raffle winners!

ASMS 2026 officially begins today. 🔬✨ We're excited to kick off the week at tonight's Welcome Reception and connect with Trailblazers. Attending? Stop by MOBILion booth #1002 to learn more about SLIM HRIM. Reserve your spot for our Breakfast Seminars: go.mobilionsystems.com/l/1089062/20...

Join us Wednesday, June 3 for the final day of the MOBILion Breakfast Seminars at #ASMS2026 ☕️ 🎤 Austin Anderson, Los Alamos National Laboratory 🎤 Jack Ryan, PhD, Merck Reserve your spot: go.mobilionsystems.com/l/1089062/2026-03-31/3gm11n

At MOBILion Systems we welcomed some future #Trailblazers for Bring Your Child to Work Day 🧪✨ From lab tours to hands-on STEM activities, the office was full of curiosity and great questions. One teen even asked: “What do I have to major in to work at MOBILion?”

Join us Tuesday at #ASMS2026 for the MOBILion Breakfast Seminars featuring: 🎤 Kevin Parker & Jessica Hoskins (AbbVie) 🎤 Birgit Schilling (Buck Institute) Exploring HRIM workflows for pharma and proteomics research. Register: go.mobilionsystems.com/l/1089062/20...

Bold scientific statement: proteomics’ biggest limitation may no longer be biology, but instrument architecture. As #ASMS2026 approaches, we’re excited to discuss why SLIM + QTOF could redefine efficiency, ion utilization, and proteomics performance. Booth #1002 | Pacific Ballroom 25

In proteomics, data quality shapes the biological conclusions researchers can trust. Birgit Schilling shared how orthogonal separation can improve data quality, reproducibility, and quantitative confidence in complex samples. ASMS 2026 breakfast seminar: go.mobilionsystems.com/l/1089062/20...

Ion mobility is moving from “helpful” to necessary. What looks like a single LC feature can contain multiple mobility-resolved species, leading to chimeric spectra. HRIM enables cleaner precursor isolation and clearer MS/MS spectra. Read more: www.biorxiv.org/content/10.6...

In a recent conversation, Komal Kedia at Merck shared how working with MOBILion's MOBIE® platform changed expectations for ion mobility data in lipidomics, enabling clearer lipid isomer separation, cleaner CCS values, and greater confidence in biological interpretation. #Trailblazers2026

We're excited to share MOBILion Systems' CTO Daniel DeBord featured in a recent profile by Leadafi, highlighting his leadership in advancing ion mobility and SLIM-based innovation. Read more: leadafi.com/executive-bi...

SLIM is evolving from a single-use solution into an enabling platform for ion mobility. Melissa Sherman discusses how MOBILion is expanding SLIM into proteomics with BILLIE + PAMAF while continuing to grow MOBIE with Agilent Technologies. instrumentbusinessoutlook.com/mobilion-exp...

Kelly Moser has been with MOBILion from the start, joining as an intern and growing into a Product Manager shaping solutions for pharma & applied markets. In this Trailblazer Spotlight, she shares key customer challenges and where she sees the biggest opportunity ahead. #Trailblazers2026

Continuous learning drives innovation. Lauren Royer Dissinger & Isabel Uribe are attending Northeastern’s May Institute to deepen expertise in computational proteomics. Proud to support their growth as they bring new insights back to MOBILion. #Trailblazers2026 #Proteomics

High separation power only matters if it performs in real workflows. HPLC + SLIM + QTOF delivers speed, cleaner separations, cleaner spectra, and more confident IDs, run after run, without sacrificing quantitation. Better inputs. Better discoveries. #HRIM #QTOF #LCMS

For Perdita Barran, the challenge isn’t collecting data, it’s trusting what it represents. With HRIM from MOBILion Systems, Inc., her lab gains added separation and structural insight for more meaningful, reproducible results. #Trailblazers2026 #IonMobility #HRIM

Advancing what’s possible in #PFAS analysis takes new ways of thinking. Scientists at Eurofins are using the combined power of MOBILion's MOBIE® with Agilent Technologies’ QTOF to enable both deep characterization and high-throughput workflows. Partnerships like this redefine what’s possible.

Most MS/MS workflows discard signal for specificity. Quadrupoles can eliminate ~99% of ions at the source due to architectural limits.95–99% duty cycle ≠ efficiency if only 1–10% of ions reach the detector. The next leap won’t come from accelerating waste, but eliminating it. #Proteomics

What if PFAS signals we report as single compounds are actually multiple structures? Environmental samples aren’t clean, interference + similar compounds complicate analysis. At Eurofins, Sarah Choyke, PhD uses high-res mobility to add separation and uncover hidden patterns. #Trailblazers2026

A growing number of companies, like Nestle' are going beyond what’s required in #PFAS analysis, and it’s becoming clear why. HRIM enables: • Separation of linear and branched isomers • Full PFAS profile in <10 min • No added chromatographic burden www.mobilionsystems.com/resources?ca...

Katie Spruance is our April MOBILion Champion 🎉 Katie shapes what it feels like to work at MOBILion. As our HR leader, she supports hiring, growth, and our team every day with a people-first mindset. She also created this award, making it even more special to recognize her.👏

Logan Pierpoint, Senior Service Engineer at MOBILion, works where there’s no playbook. Every lab is different. Every challenge is new. Working alongside Agilent Technologies, he’s solving problems in real time to make sure our customers are supported. #Trailblazers2026

For a scientist, a first conference talk isn’t just a talk, it’s a milestone. At Pittcon 2026, Lauren Royer Dissinger delivered her first presentation, showcasing PAMAF™+ HRIM for deeper proteome coverage and high-throughput workflows. We’re proud so proud of Lauren! #Trailblazers2026 #Proteomics

We generated a mirror plot after HRIM removed interference. A scientist thought we plotted the pure standard twice. That’s the shift. Cleaner spectra. Less manual review. Stronger AI/ML. When data quality improves, everything downstream follows. #Trailblazers2026

Proteomics has made huge progress, thousands of proteins in a single run is now routine. But we’re still only sampling the proteome. Limited coverage, missed modifications, and lost signal mean much of biology remains invisible. The next leap is rethinking how we measure. #Trailblazers2026

Abandoning the Quadrupole with PAMAF™ That’s not the full story. SLIM + PAMAF shifts LC-MS performance from duty cycle to ion utilization, enabling 100× signal gains and >1000 Hz speeds on a QTOF. Read more: www.genomeweb.com/proteomics-p... #Proteomics #PAMAF

Sometimes what looks like one peak… isn’t. Co-eluting compounds make it hard to tell what you’re seeing, impacting confidence. At Los Alamos, Austin Anderson’s team is evaluating MOBIE® to add a second separation dimension and resolve LC overlaps. #Trailblazers2026

A birds eye perspective on the company proposing quadrupole-free proteomics. Additionally, see which vendors are suggested to most benefit from Mobilion's IMS approach www.genomeweb.com/proteomics-p...

The MOBILion team stepped out of the lab and into the kitchen, volunteering at Ronald McDonald House to prepare meals for families whose children are receiving medical care. Grateful to support an organization that provides comfort and community when families need it most.

Two-dimensional separations solve problems 1D methods can’t. A new study from Oliver Schmitz’s lab adds multidimensionality at the ion source with rapidly switchable ESI + plasma ionization, paired with HRIM from MOBILion on an Agilent QTOF. Read: pubs.acs.org/doi/pdf/10.1...

Behind every high-resolution measurement is the need to turn complex data into meaningful insight. As an Informatics Scientist at MOBILion, Lauren Royer Dissinger ensures ion mobility data is reproducible, high-quality, and actionable for researchers. #Trailblazers2026

Some of the hardest challenges in proteomics and metabolomics appear after measurement. As Gary Patti noted, faster workflows often trade certainty for speed. Adding another separation dimension is helping labs gain confidence without added complexity. #Trailblazers2026

The metallome is one of my favorite omes. Can’t wait until it’s front and center!

“This complexity calls for an additional dimension of separation beyond chromatography.” Genentech demonstrates HRIM resolving PS diastereomers across therapeutic oligos, turning a trial-and-error challenge into a predictable analytical strategy. pubs.acs.org/doi/10.1021/...

“What would you tell a girl who thinks science isn’t for her?” For International Women & Girls in Science Day, we asked the women of MOBILion to share their thoughts. One message stood out: there’s more than one way to belong in science. What would you say? 👇 #WomenInSTEM

Using ion mobility has often meant trading breadth for focus. For Christopher Chouinard, high-resolution ion mobility changed that, enabling wide, untargeted separations that deliver clearer identification in complex, real-world samples. #Trailblazers2026

Our CTO Daniel DeBord is heading to US HUPO 2026 with 3 presentations you won’t want to miss: ⚡ Lightning Talk + Poster: Waste Not, Want Not (single-cell proteomics) 🧬 Poster: From Blind Spots to Breakthroughs (PTM analysis) Connect with Daniel or Mick Greer while you’re there. #Trailblazers2026

MS2 speed limits proteome depth and completeness. When acquisition is slow, many peptides never get fragmented, driving undersampling and missing values. SLIM separates precursors in time to enable >500 Hz MS2 with high ion utilization. www.biorxiv.org/content/10.1...

Big congratulations to our CEO, Melissa Sherman, Ph.D., on being named a 2026 Women of Precision Medicine Honoree by DeciBio Consulting. Proud to see her recognized among leaders shaping the future of precision medicine. www.decibio.com/insights/wom...

MOBILion Systems' CTO Daniel DeBord will be presenting at the Gordon Research Conference: "Mass Confusion? High Resolution Ion Mobility Brings Clarity to Ion Fragmentation Analysis” 📅 Feb 25 | 🕚 11:50 AM – 12:20 PM #Trailblazers2026

For years, ion mobility meant tradeoffs: accuracy vs speed. Tim Causon found @mobilionsystems.bsky.social HRIM delivered stable, reliable data in routine use, repeatable CCS, aligned fragments, and separations that distinguish close compounds without slowing LC. A clearer standard. #Trailblazers2026

Progress in pharma doesn’t usually come from a single breakthrough. It happens steadily over time, with each step bringing greater clarity. In Pharma’s Almanac, @mobilionceo.bsky.social Melissa Sherman reflects on key advances. 🔗 pharmasalmanac.com/articles/looking-back-over-the-last-30-years

For years, lipidomics faced trade-offs: depth or throughput, accuracy or reproducibility. That constraint no longer holds. A new study shows HRIM delivers ~0.1% interlaboratory CCS precision while enabling deep triglyceride characterization, turning “or” into “and.” pubs.acs.org/doi/10.1021/...

Trailblazers aren’t defined by titles or timelines. They’re defined by the courage to do things differently, questioning assumptions, pushing limits, and moving forward when others say “this is how it’s always been done.” This is where it begins. #Trailblazers2026 #ScientificInnovation

As 2025 wraps, we’re grateful for a year of curiosity, collaboration & breakthroughs with our scientists, partners & customers. We look forward to the new challenges, milestones & discoveries that lie ahead in the new year. Warmest wishes from all of us at MOBILion Systems.

"We've always done it that way" costs drug developers time, money and potentially better therapies for patients. Listen to our podcast feature to hear us explain how traditional LC-MS workflows create blind spots, missing PTMs and slowing drug development: deeptechdigest.com/biotech/base...

Chimeric MS2, <1% ion utilization, 90% signal loss, workarounds dressed up as innovation. All problems that trace back to one thing: the quadrupole. Maybe it's time to stop believing it's all we have. analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.... #IonMobility #itSLIM @asms.org

It’s a great idea - what if IMS was as selective as a quadrupole?

Happy Thanksgiving from all of us at @mobilionsystems.bsky.social. This year we reached new milestones by pushing boundaries with our customers, partners & team. Thank you for being part of our journey. Wishing you a wonderful holiday with your loved ones.

Nikolai Slavov and Daniel DeBord and share how HRIM is transforming proteomics and beyond in The Analytical Scientist. Read how SLIM and other ion mobility platforms are redefining what’s possible: theanalyticalscientist.com/issues/2025/... #Proteomics