Jakub Kopal
@jakubkopal.bsky.social
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📥 85
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#MSCActions
postdoctoral fellow at University of Oslo
pinned post!
Out now in
#natBME
: We explore how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD).
nature.com/articles/s41...
4 months ago
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Out now in
#natBME
: We explore how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD).
nature.com/articles/s41...
4 months ago
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#Multimorbidity
is a pressing challenge in health care. We dissect its genetic architecture across mental and physical health, revealing shared and distinct links between brain structure, psychiatric disorders, and cardiometabolic disease.
www.medrxiv.org/content/10.1...
6 months ago
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reposted by
Jakub Kopal
Pravesh Parekh
6 months ago
Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects!
www.biorxiv.org/content/10.1...
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FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets
Linear mixed-effects (LME) models are commonly used for analyzing longitudinal data. However, most applications of LME models rely on random intercepts or simple, e.g., stationary, covariance. Here, w...
https://www.biorxiv.org/content/10.1101/2025.05.09.653146v1
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Understanding
#Parkinsons
subtypes is key to more targeted RCTs & better therapeutics! 🧠 Our new study finds that LRRK2 PD patients show milder cortical atrophy, with preserved temporal & occipital regions compared to sporadic PD.
#LRRK2
#dataviz
www.medrxiv.org/content/10.1...
8 months ago
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reposted by
Jakub Kopal
Eivind Ystrom
10 months ago
Want to get out of Dodge? Do a postdoc
@uio.no
! You will be using the MoBa study and registers to study intergenerational transmission and GxE for
#MentalHealth
and
#education
using
@behaviorgenetic.bsky.social
and
@pgcgenetics.bsky.social
approaches. Please share!
www.jobbnorge.no/en/available...
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Postdoctoral Fellowship in Mental Health Research (272560) | University of Oslo
Job title: Postdoctoral Fellowship in Mental Health Research (272560), Employer: University of Oslo, Deadline: Monday, February 24, 2025
https://www.jobbnorge.no/en/available-jobs/job/272560/postdoctoral-fellowship-in-mental-health-research
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