And our #BiophysicsWeek affiliate event begins! Dialogues in the Midst brings together bright group of scientists - today is all about doing some free energy perturbation simulations. Moderated by @tfguclu.bsky.social | sponsored by @eurocc.bsky.social

Biophysics Week 2025 – Final Day! It’s been an incredible week of discovery, connection, and celebration! Don’t miss the last round of events and resources—celebrate with us! #BiophysicsWeek

An audio summary of this paper is at sciencecast.org/casts/bezkml...

Our approach introduces a protein-centric view on the competitive inhibition mechanisms and allows us to interpret the effect of the mutations on the substrate-bound and the inhibitor-bound forms of the enzyme separately -- by Ebru Cetin, Haleh Abdizadeh, @ara-17.bsky.social, @cananatlgn.bsky.social

Can we determine the positions whose simulataneous perturbation would lead to maximum overlap between two conformers? We solve this problem and demonstrate its utility on sensor design -- by @mberksoz.bsky.social, @ara-17.bsky.social, Burak Kocuk and @cananatlgn.bsky.social

BAGEP 2025 Başvuruları Devam Ediyor! Son başvuru tarihi: 27 Ocak 2025, Pazartesi, saat 14.00. Detaylar👇 bilimakademisi.org/14633-2/

We have just moved here, and trying to get settled. Let's start with the good news of the day: Our manuscript on 'Ranking Single Fluorescent Protein-Based Calcium Biosensor Performance by Molecular Dynamics Simulations' was the #HighlightOfTheWeek by @JCIM_JCTC. x.com/JCIM_JCTC/st...