Feige Lab (@feigelab.bsky.social)

New study on #MitoCa2+ during muscle #aging with a novel #polyphenol for dietary intervention. Great collaboration with UmbertoDeMarchi, Cristina Mammucari, Rosario Rizzuto, Keith Godfrey & great team ! #sarcopenia #nutrition #aging #mitochondria www.cell.com/cell-metabol...

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Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance Gherardi et al. identify that aging and disability impair mitochondrial calcium uptake in skeletal muscle via MCUR1. Food-derived polyphenols increase the import of calcium in mitochondria by binding ... https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00417-0