ton rabelink
@trabelink.bsky.social
📤 28
📥 64
📝 5
Ex vivo preservation of donor kidneys is crucial to improve transplant outcomes—and may allow future organ repair. But the challenge remains: how to preserve function for longer periods?
4 months ago
1
0
0
reposted by
ton rabelink
Nature Reviews Bioengineering
6 months ago
Kidney transplantation is the only definitive treatment for end-stage kidney disease. This article explores challenges in renal replacement and highlights the clinical potential of bioengineering approaches to restore kidney function:
loading . . .
Replacing renal function using bioengineered tissues - Nature Reviews Bioengineering
Renal function can be replaced by bioengineered kidney tissue. This Review discusses in vivo kidney engineering, xenotransplantation, blastocyst complementation and stem-cell-derived kidney tissue engineering as approaches for renal replacement therapy.
https://go.nature.com/3X6jiHk?utm_source=bluesky&utm_medium=social&utm_campaign=natrevbioeng
0
3
2
reposted by
ton rabelink
Jan Żylicz
7 months ago
In a new preprint with
@trabelink.bsky.social
, T. Moritz &
@bonalditiziana.bsky.social
, we find that implantation leads to rewiring of the TCA cycle to support histone acetylation turnover and exit from naïve pluripotency. Gr8 work of
@elenikafkia.bsky.social
D. Pladevall-Morera et al.
rb.gy/clk8vm
loading . . .
TCA cycle rewiring underpins implantation and histone acetylation programming
Metabolism has emerged as a key regulator of stem cell differentiation and their epigenomes. This coupling is particularly evident during the exit from naive pluripotency in vitro. However, our unders...
https://rb.gy/clk8vm
4
22
5
you reached the end!!
feeds!
log in
