Americans spend 90% of their time indoors, breathing air that's often dirtier than what's outside. The hidden cost? Asthma, COPD, heart disease, and costly outbreaks of disease.

1Day Sooner is a nonprofit that advocates for healthy volunteers in high-impact clinical trials and today we recognize the researchers and participants who make trials possible! #ClinicalTrialsDay #CTD2026

What’s happening? A clinical trial tested a vaccine designed to prevent illness from Epstein-Barr virus, the common virus best known for causing mono.

Meet Roopesh! He’s one of the remarkable team of volunteers who make up 1Day Sooner’s Participant Council. You can read his full profile on our website to learn more about how trial participation shaped his advocacy commitments!

We're launching a series introducing the members of our team and the incredible work they do at 1Day Sooner! First up is Paul Zimmer-Harwood, Research Lead for Clinical Trials, whose focus has been on Hepatitis C vaccine development.

Trials we love! What’s happening? NIH is recruiting healthy adults ages 18–29 for a Phase 1 study testing two Epstein-Barr virus vaccine candidates.

1Day Africa signed onto a declaration to improve pandemic preparedness across Africa called the “Nairobi Declaration on African Health Security and Collaborative Disease Surveillance.”

@bsky.app 1Day Sooner's Participant Council brings together research volunteers from around the world together to share advice, lived experience, and perspectives on trial participation.

What’s happening? A challenge trial in Kenya tested malaria vaccines and showed that route of infection matters. Vaccines targeting the circumsporozoite protein protected volunteers when parasites entered through the skin, but not when injected straight into the bloodstream.

What’s Happening: This study looks at how psilocybin, along with a participant’s mindset and environment, affects the psychedelic experience and mental well-being. Volunteers receive either psilocybin or a placebo in different conditions.

This is the first in a series spotlighting the volunteers who make up 1Day Sooner's Participant Council: Meet Angelique Mseteka! Angelique first participated in a clinical trial to serve her community, and now she's passionate about helping others to do the same!

What’s happening: Researchers tested a first-in-human mRNA vaccine for Nipah virus and found it was safe and triggered strong immune responses in healthy adults.

We’re starting a new series called “Trials We Love,” in which we'll highlight clinical trials that our team is excited about! Our goal is to draw attention to opportunities to participate in research and share information about impactful trial results!

We are HIRING! 1Day Sooner is hiring a Policy Lead to drive the policy agenda of our Clinical Trial Abundance (CTA) program. If this looks like you, please APPLY: 1daysooner.org/jobs/

The first legally binding global treaty on pandemic preparedness, the WHO Pandemic Agreement, was adopted in May 2025. A new BMJ Global Health analysis co-authored by 1Day's Zach Kafuko gh.bmj.com/content/11/2... argues that its success hinges on how Africa shapes implementation.

Last month, 1Day Sooner convened the first meeting of its Participant Council, bringing together 19 healthy research volunteers from 8 countries to help shape the future of clinical trial participation.

Sub-Saharan Africa bears the highest global disease burden—yet <3% of clinical trials take place there, and very few are early-phase. That means key safety and dosing decisions are often made without data from the populations most affected. www.nature.com/articles/s44...

The FDA’s decision to publish Complete Response Letters (CRLs) is a big step forward for transparency. Our new report explains how AI can help make this shift sustainable over time. 1daysooner.org/wp-content/u...

Biotech loses an enormous amount of knowledge every year—and almost no one talks about it. When startups fail, their regulatory and clinical data usually disappears with them. A new initiative—called CTD Commons wants to change that. www.ctdcommons.org

1Day Africa's grant program for African researchers is now accepting applications! Please share far and wide! The deadline for applications is February 28th.

1/2 Progress in vaccine development only happens when people are willing to step up. Challenge trials are one of the most powerful tools we have for speeding lifesaving vaccines. If we want faster, more equitable global health outcomes, we need to expand and support this research model.

The U.S. is sitting on a goldmine of health data. The data that exists could transform medicine and save lives. Right now it’s locked in silos across Medicare, Medicaid, VA & more. It’s time to treat health data like public infrastructure. 🔗 city-journal.org/article/hhs-health-data-rfk

Tomorrow, we're joining global leaders, policymakers, scientists, and health experts as a featured speaker at the “Healthy #IndoorAir: A Global Call to Action” event, an official side event of #UNGA80. Watch it live at 3 p.m. EDT: bit.ly/4nfJbj5

We made water safe with filtration & disinfection. Now we can do the same for air with ventilation, filtration, and germicidal light, as illustrated in our latest @worksinprogress.bsky.social piece. (1/10)

New Nature Reviews Immunology paper: "Targets of protective immunity & opportunities in hepatitis C virus vaccine development" explores the current landscape, including subunit, virus-like particle, viral vector, DNA & RNA vaccines, and controlled human infection models. Read at bit.ly/4md5EvH.

We've launched the first-ever Cooperative Participant Organization (CPO) for clinical trials, connecting academic researchers with motivated healthy volunteers for crucial studies. Community trust + expertise from former participants = game-changing support for researchers. bit.ly/4mlY3ey

Proud to have signed on to this act. Looking forward to seeing progress on indoor air quality!

We are hiring! If you are passionate about reducing the burden of infectious diseases worldwide, 1Day is seeking contractors to work on our African Medicines Agency engagement and using AI in the FDA projects. Apply today at www.1daysooner.org/jobs/.

🚨 We're hiring a People Operations Lead! 🚨 🧠Own HR, onboarding, benefits, & culture. 🌎Remote-first international nonprofit. 🤝 High autonomy + direct access to leadership. 💼HR pros with 2+ yrs. of experience. Apply by July 18. www.1daysooner.org/jobs/

Last chance to register for tomorrow's webinar! bit.ly/4le0yzu

Join us & @scientistsorg.bsky.social on 6/24 for a webinar on opportunities to integrate AI in the HHS. Experts will discuss implementation case studies, talent pathways like a proposed AI Corps, research opportunities, and public-private collaboration. Register today! bit.ly/4le0yzu

Join us in D.C. for a happy hour on fair compensation in clinical trials! Meet the authors of the new American Journal of Bioethics open letter on ethical pay for participants & connect with changemakers over drinks. Register today: bit.ly/4e5yHz2

ICYMI: 64 experts have published an open letter in The American Journal of Bioethics, calling for a reexamination of entrenched attitudes toward payment for clinical research participation. bit.ly/4kWd06R

Check out our latest news in our May newsletter: mailchi.mp/1daysooner.o....

As the FDA faces significant staffing reductions, there could be ripple effects for US companies & leadership in the biomedical space, as well as for other countries that depend on FDA's leadership to enable access to key health tools. @ghtcoalition.org bit.ly/3T0S1U8

Why are we so afraid to fairly compensate research participants? 64 experts challenge the idea that payment = undue influence. Read our open letter in The American Journal of Bioethics highlighting the pitfalls of excessive concern over payment to research participants. bit.ly/43vpdbo

On #ClinicalTrialsDay, we thank the volunteers who have stepped forward to participate in human challenge studies. Your selflessness and commitment to advancing science have played a vital role in improving public health. Sign up to learn more on how to participate: www.1daysooner.org/volunteer/.

Bipartisan momentum for U.S. biotech: The National Biotechnology Initiative Act of 2025 would create a White House-led office to coordinate federal biotech strategy across security, economy & innovation. www.biotech.senate.gov/press-releas...

Policymakers from 11 African countries met for #COPEMA's first regional summit to fight malaria. We are proud to see our cost analysis shared by another presenter and to have 1Day Africa's Zach Kauko share our work! Read our cost analysis here: www.1daysooner.org/cost-effecti....

On #WorldMalariaDay, we’re reminded that access & vaccine costs can mean life or death. 🦟 Malaria caused 249M cases & 608K deaths in 2022 alone. It’s time to embrace this year's theme: "reinvest, reimagine, reignite." 1Day Africa’s Dir spoke with The Economist on bridging this gap. bit.ly/4cPGeBs

📣April newsletter drop! Check out our latest and greatest: bit.ly/3Yeo86a.

New study in Vaccine says COVID human challenge trials (HCTs) aren’t “too risky”—they may be low or even minimal risk for eligible volunteers. Time to reassess how we evaluate HCTs in pandemics. bit.ly/3YeLngi

ICYMI, our latest webinar, "Volunteering in Controlled Human Infection Model Studies," features a panel of experts answering all your burning questions about participating in a human challenge trial. Watch at bit.ly/4igtDrT.

We are hiring a Volunteer Coordinator for our Cooperative Participant Organization. We are seeking a person ✔️ Passionate about advocating for clinical trial participants ✔️ Skilled in executing targeted outreach strategies ✔️ Ideally located in Europe or the United Kingdom Apply today: bit.ly/4cAwBGp

Our full response to the U.S. government's RFI on AI and public health is now public! We dig into how AI can help us speed up biomedical research and be a tool for good. Read it here: bit.ly/42cU0dG

💥 A blinded #StrepA human challenge PK/PD RCT 💥 All-star collaboration between @thekidsau.bsky.social & #MCRI & #UWA. @hicvac.bsky.social @1daysooner.bsky.social Thanks @onisillos.bsky.social @lancetmicrobe.bsky.social for support of human challenge research! www.thelancet.com/journals/lan...

New in Global Forum: "Unearthing the FDA’s Treasure Trove: Using AI to Revolutionize Drug Development" explores how AI can use clinical trial data to unlock smarter, faster, and more efficient drug development. A must-read for regulatory affairs, data science, or drug R&D. bit.ly/3Yui1uk

Want to be part of medical breakthroughs? Join our webinar this Thursday to learn about volunteering in human challenge trials and connect with medical experts and fellow volunteers in a live Q&A. bit.ly/4c67LON hashtag#CHIMs hashtag#MedicalResearch hashtag#Volunteer

We're 1 week away from our "Volunteering for Controlled Human Infection Model Studies" webinar. Register today to learn about this fast-growing medical research and how to get involved: bit.ly/4c67LON. Even if you can't attend, a recording will be sent to all registrants.