Eilidh Rivers
@eilidhrivers.bsky.social
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PhD student | MRC-UofG Centre for Virus Research 🦠🏴 E3 ligases in innate immunity (she/her)
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Eilidh Rivers
Fletcher Lab
20 days ago
Pre-print: our description of RZ affiliate ZNFX1 is now online. On binding viral RNA, ZNFX1 generates parallel Ub currents, coordinating Ub-dependent RNA silencing and aggregate resolution. Huge effort from first authors Dan Squair and
@eilidhrivers.bsky.social
www.biorxiv.org/content/10.1...
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ZNFX1 uses two-component ubiquitin circuitry to quarantine viral RNA
The detection of viral RNA inside cells triggers a diverse range of antiviral responses, including global translation inhibition, interferon secretion and RNA sequestration. Mutations in the gene ZNFX...
https://www.biorxiv.org/content/10.1101/2025.09.05.674436v1
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