Larissa Ferguson (@lariferg.bsky.social)

DeorphaNN: Virtual screening of GPCR peptide agonists using AlphaFold-predicted active state complexes and deep learning embeddings G protein-coupled receptors (GPCRs) are important cell surface receptors involved in numerous physiological processes. Although peptides are the cognate ligands for many of these receptors, identifyin... https://www.biorxiv.org/content/10.1101/2025.03.19.644234v1