My highlight of 2025: the first #microelectrode #BCI for spinal cord injury in Europe! 🦾⚡️🧠 🎥 (feature in German) www.ardmediathek.de/video/gesund...

Frequent BCI recalibration due to changing neural activity mark a significant hurdle in long-term BCI engagement. Researchers at stanford now demonstrate a clever approach enabling unsupervised decoder adaptation by infering task labels and reinforcing the neural decoder #neuroskyence

New study challenges the idea of a unified decision network: Neuropixel recordings in primate OFC showed robust encoding during value-based choices but near-silence during perceptual decisions, even when rewards are at stake. #RewardSignals #neuroskyence www.biorxiv.org/content/10.1...

DARPA-backed brain-computer interface just published in Nat. Electronics: Ken and colleagues present a fully implanted, 50-μm thick ECoG with 65.000 channels on a 256x256 grid. Their system wirelessly transmits power and signals to a relay-coil outside the skull #neuroskyence #neuroAI #compneuro

Speech decoding on the basis of single words has so far been limited to intracranial recordings. Scientists demonstrated the feasibility of non-invasive language decoding using EEG and MEG, finding that more training data consistently increases model performance #neuroskyence #compneuro #neuroAI

Changing behavior with ultrasound 🔊🧠 Focused ultrasound is shown to reliably modulate deep brain areas such as the nucleus accumbens, comparable to DBS. Stimulation during a reinforcement learning task altered reward expectation, learning curves and task strategy #neuroAI #neuroskyence #compneuro

Insular neural interfaces Cognitive error signals in the anterior insula propagate toward prefrontal cortex when a BCI fails to follow the user’s intention. Real-time integration enables a self-correcting neural interface that compensates for its own decoder misclassifications #neuroskyence

Thalamus for vision BCIs Scientists have recorded single neurons in the human LGN for the first time, revealing how it links the retina to visual cortex. When one eye is closed, neurons tuned to that eye reduce their activity, while neurons tuned to the open eye increase in spikerate #neuroskyence

New article in Nature showing that the superior temporal gyrus (STG) encodes language-specific features stronger when listening to the native language. Bilinguals on the other hand shared this higher-level tuning across both of their familiar languages @changlabucsf.bsky.social #neuroskyence

A race to the brain 🧠 Paradromics has just received FDA IDE approval to implant their micro-electrode array in human participants. The neuralink competitor will soon start recruiting patients with speech/motor impairments at UC Davis, Mass General Hospital and U Michigan #neuroskyence

Human superior temporal gyrus (STG) encodes the progression of a word as it unfolds in time. The neural activity tracks relative position within the word, regardless of its length, and resets at each new word boundary. #neuroskyence @changlabucsf.bsky.social

Towards a bidirectional visual neuroprosthesis 👁️⚡️ Spiking activity near intracortical stimulation sites proved to accurately predict the brightness and sharpness of perception. Using these signals in real time could one day optimize the individualized experience of each phosphene #neuroskyence

Jeff Bezos increases his bet on Synchron The company behind the stentrode just raised $200M in Series D funding, led by Double point ventures, Bezos Expeditions and ARCH ventures. The funding will be used to develop smaller stentrodes reaching multiple brain regions 🧠 #neuroskyence

Towards a unified “brain language”?

Treating OCD with neurotechnology Researchers at UCSF used iEEG to map brain circuits in severe OCD, identifying the ventral capsule as bridge between the prefrontal cortex and limbic system. Multi-area DBS implantation led to rapid symptom improvement 🧠 #neuroskyence @changlabucsf.bsky.social

DBS for epilepsy ? Researchers demonstrated that stimulation of the thalamus helped reduce seizures by over 80%. Their approach showed a reduction in epileptiform discharges, in line with the nuclei's critical role in seizure termination #neuroskyence #neuroAI #neuroscience

Bigtime publication on retinal prosthesis @science.xyz implanted 38 patients with macular degeneration with the PRIMA subretinal implant. Paired with camera-equipped glasses, the system improved central vision in 80% of participants, allowing them to read again @maxhodak.bsky.social #neuroskyence

🧠 In this behind-the-scenes video, Neuralink's surgery engineering team shows how they build realistic head and brain models from patient CT and MRI scans. These "proxies" let surgeons rehearse each procedure in advance. 🎥 youtube.com/watch?v=WhG-...

A big push for #BCI and #neurotechnology in Europe! We implanted our second microelectrode array #BCI @tum.de. Huge thanks to our pioneer and to fantastic colleagues in #Neurosurgery and #Robotics #Machine #Intelligence 🧠🦾🧪 #neuroskyence @neuroengineering.bsky.social www.tum.de/en/news-and-...

Ultrasound maps deep brain function over months Scientists used functional ultrasound imaging to record from primate parietal cortex over months. Their method combines high spatial resolution and long-term stability, revealing direction-tuned saccadic neural patches #neuroskyence #compneurosky

OpenNeuro @openneuro.bsky.social just hit a huge milestone: 1500 datasets! Congrats to the team on making this project so successful over the last 7 years.

🧠⚡️ Can transcranial alternating current stimulation (tACS) truly rhythmically modulate brain activity in humans? More than 30 labs are joining forces in the tACS Challenge, a global effort to test one of brain stimulation's biggest questions. 🧵1/5

Precision Neuroscience published their high-density ECoG in Nature Biomed. Eng. The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution. #neuroskyence @precisionneuro.bsky.social

Can we combine neural data across individuals to improve speech BCIs? A recent study used transfer learning on distributed iEEG recordings to enhance speech decoding. By learning shared latent manifolds, their cross-subject model outperformed individual models in a speech motor task. #neuroskyence

Neuropixel's newest ultra-high density probe enables larger neuronal yield (up to 2x), with over 6000 recording channels. #neuroskyence

Optimizing stimulation patterns for visual implants 👁️ Check out @mbeyeler.bsky.social's recent study on using spiking activity to adapt stimulation parameters for more stable and reliable perception #neuroskyence #bci

How does intracortical microstimulation (ICMS) affect the brain? ICMS affects both vascular and immune responses. Higher currents increase blood-brain barrier leakage, letting substances enter surrounding tissue. Soon after, microglia activate and cluster around highly active regions #neuroskyence

Better neural decoding using connectomics and emotional states? Check out @julianneumann.bsky.social newest study in Nature Biomed. Eng! #neuroskyence #bci #compneurosky

How does the body regulate blood pressure after SCI? Scientists mapped the precise nerve circuits causing dangerous spikes in mice, rats, and humans. By stimulating these circuits with epidural electrical stimulation, they activated a competing pathway that stabilized blood pressure. #neuroskyence

Blood pressure control after SCI has been challenging — until now. Swiss and Canadian researchers developed an implantable system that epidurally stimulates three thoracic segments, triggering a strong pressor response and rapidly reducing hypotensive symptoms. #neuroskyence #sci #onward

How far can intravascular electrodes reach? Scientists miniaturized stentrode-like electrodes to access small, deep cortical veins. Their probe goes beyond large vessels used by Synchron, enabling recordings from hand and speech regions with ECoG-level quality. #neuroskyence #bci #synchron

Might focused ultrasound one day replace DBS? UK Scientists built a 256-panel focused ultrasound helmet that can precisely target deep brain regions. Using theta-burst TUS, they stimulated the LGN and found visual cortex activity with effects lasting up to 40 minutes. #neuroskyence #ultrasound

Neuralink update 🧠 • 2 new patients implanted in Canada, marking first trials outside the US • US patent office rejects ‘telepathy’ and ‘telekinesis’ trademarks, as they were previously claimed by a lucid dreaming startup #neuroskyence #bci #neuralink

A password protected inner speech BCI 🧠 Researchers showed that inner speech can be decoded from motor cortex, offering a less fatiguing alternative to attempted speech. To ensure user privacy, the system only activated when participants said 'chitty-chitty-bang-bang'. #neuroskyence #neuro #bci

Sam Altman just got into BCI by backing Merge Labs 🧠 - Valued at $850M after a $250M raise - Developing high-performance, non-invasive brain-computer interfaces - Their bet: focused ultrasound + neuronal gene editing (sonogenetics) #neuroskyence #neuropapers #openAI #BCI

German BCI startup CorTec announces first in-human use of a fully implanted ECoG grid 🇩🇪🧠 The Seattle-based trial, led by Jeffrey Ojemann (U Washington) and Steven Cramer (UCLA), tests if cortical stimulation can aid upper limb recovery of stroke patients. #neuroskyence #neuropapers

Neuralink update 🧠 - P8 and P9 have been implanted within one day - 20 participants are expected by the end of 2025 - Bloomberg estimates $1B revenue by 2031, generously assuming 20k implantees

Meta published their EMG wristband in Nature 📄 They developed a non-invasive neuromotor interface using a wrist-worn device for decoding gestures and handwriting. Its performance scales with the number of participants and can be further enhanced through personalized user tuning. #Neuropapers #CTRL

Nudge just secured $100M Series A funding 💰 The company is developing whole-brain ultrasound interfaces to target psychiatric and cognitive disorders. They plan to enhance the Nudge Zero and validate its impact through clinical studies.

Great to see more BCI developments in asia!

Ripples segment experiences during natural viewing Scientists observed hippocampal ripples peak at event boundaries of movie scenes. Meanwhile, ripples in temporal cortex rise within events and predict which moments will be remembered. These fast oscillations seem to support memory formation.

How do central brain areas work together to create movement? New work from the Courtine lab showed that premotor areas encode movement plans (the why), while primary motor and somatosensory cortices handle execution (the how). Control flows through low-dimensional subspaces from plan to action.

🧠🕹️ Neuralink just shared an update: - 7 participants implanted (SCI & ALS) - Hand-knob area for now, speech motor cortex later this year - First vision BCI in 2026 with deeper threads (5cm/2inch) - 10k channels in 2027 - Full-brain coverage in 2028 for psychiatric diseases, epilepsy and pain