Neuroengineering
@neuroengineering.bsky.social
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📥 117
📝 166
Your (non-addictive) dose of neurotechnology news 🧠⚡️
Human superior temporal gyrus (STG) encodes the progression of a word as it unfolds in time. The neural activity tracks relative position within the word, regardless of its length, and resets at each new word boundary.
#neuroskyence
@changlabucsf.bsky.social
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Human cortical dynamics of auditory word form encoding
We perceive continuous speech as a series of discrete words, despite the lack of clear acoustic boundaries. The superior temporal gyrus (STG) encodes …
https://www.sciencedirect.com/science/article/pii/S0896627325007925
about 8 hours ago
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Towards a bidirectional visual neuroprosthesis 👁️⚡️ Spiking activity near intracortical stimulation sites proved to accurately predict the brightness and sharpness of perception. Using these signals in real time could one day optimize the individualized experience of each phosphene
#neuroskyence
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Neural correlates of phosphene perception in blind individuals: A step toward a bidirectional cortical visual prosthesis
Visual prostheses are improved by decoding neural signals to predict and control visual perceptions in blind individuals.
https://www.science.org/doi/10.1126/sciadv.adv8846
about 13 hours ago
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Jeff Bezos increases his bet on Synchron The company behind the stentrode just raised $200M in Series D funding, led by Double point ventures, Bezos Expeditions and ARCH ventures. The funding will be used to develop smaller stentrodes reaching multiple brain regions 🧠
#neuroskyence
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Neuralink Rival Synchron Raises $200 Million for Brain Implant
Synchron Inc. raised $200 million to advance its work building brain implants that doctors can insert through blood vessels, avoiding the costly and high-risk surgeries necessary to install devices ma...
https://www.bloomberg.com/news/articles/2025-11-06/neuralink-rival-synchron-raises-200-million-for-brain-implant?accessToken=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJzb3VyY2UiOiJTdWJzY3JpYmVyR2lmdGVkQXJ0aWNsZSIsImlhdCI6MTc2MjQzNjEwNSwiZXhwIjoxNzYzMDQwOTA1LCJhcnRpY2xlSWQiOiJUNTQ4NTVHUFFROUswMCIsImJjb25uZWN0SWQiOiJDNDAzNzQ1NDNFQkI0RDk3OEQ1MzU4M0E4OTQwNkEzMyJ9.o2-L5ipXjo3WIB_w4SW74MAjPTDSwy8WRBY7NPK3BYA&leadSource=uverify%20wall
1 day ago
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Towards a unified “brain language”?
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3 days ago
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Treating OCD with neurotechnology Researchers at UCSF used iEEG to map brain circuits in severe OCD, identifying the ventral capsule as bridge between the prefrontal cortex and limbic system. Multi-area DBS implantation led to rapid symptom improvement 🧠
#neuroskyence
@changlabucsf.bsky.social
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Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity - Translational Psychiatry
Translational Psychiatry - Invasive brain mapping identifies personalized therapeutic neuromodulation targets that suppress OCD network activity
https://www.nature.com/articles/s41398-025-03690-z
4 days ago
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DBS for epilepsy ? Researchers demonstrated that stimulation of the thalamus helped reduce seizures by over 80%. Their approach showed a reduction in epileptiform discharges, in line with the nuclei's critical role in seizure termination
#neuroskyence
#neuroAI
#neuroscience
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Thalamocortical hodology to personalize electrical stimulation for focal epilepsy - Nature Communications
Over 50 million people worldwide suffer from epilepsy, and many patients remain resistant to medication. Here, the authors hypothesized that targeting thalamic nuclei with precise anatomical...
https://www.nature.com/articles/s41467-025-64922-w
12 days ago
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Bigtime publication on retinal prosthesis
@science.xyz
implanted 38 patients with macular degeneration with the PRIMA subretinal implant. Paired with camera-equipped glasses, the system improved central vision in 80% of participants, allowing them to read again
@maxhodak.bsky.social
#neuroskyence
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Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD | NEJM
Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in ...
https://www.nejm.org/doi/full/10.1056/NEJMoa2501396
18 days ago
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#neuroskyence
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19 days ago
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🧠 In this behind-the-scenes video, Neuralink's surgery engineering team shows how they build realistic head and brain models from patient CT and MRI scans. These "proxies" let surgeons rehearse each procedure in advance. 🎥
youtube.com/watch?v=WhG-...
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How Elon Musk’s Neuralink Builds Fake Brains
YouTube video by Core Memory
https://youtube.com/watch?v=WhG-o3M9VGU
24 days ago
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reposted by
Neuroengineering
Jacob Lab
25 days ago
A big push for
#BCI
and
#neurotechnology
in Europe! We implanted our second microelectrode array
#BCI
@tum.de
. Huge thanks to our pioneer and to fantastic colleagues in
#Neurosurgery
and
#Robotics
#Machine
#Intelligence
🧠🦾🧪
#neuroskyence
@neuroengineering.bsky.social
www.tum.de/en/news-and-...
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Brain-computer interface for a patient with quadriplegia
A team at the Technical University of Munich’s TUM University Hospital has implanted a brain-computer interface in a patient paralyzed from the neck down.
https://www.tum.de/en/news-and-events/all-news/press-releases/details/brain-computer-interface-for-a-patient-with-quadriplegia
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Ultrasound maps deep brain function over months Scientists used functional ultrasound imaging to record from primate parietal cortex over months. Their method combines high spatial resolution and long-term stability, revealing direction-tuned saccadic neural patches
#neuroskyence
#compneurosky
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Functional ultrasound neuroimaging reveals mesoscopic organization of saccades in the lateral intraparietal area - Nature Communications
The functional organization of the posterior parietal cortex (PPC) for guiding eye movements has remained unknown. Here, the authors use functional ultrasound neuroimaging to reveal small, tuned clust...
https://www.nature.com/articles/s41467-025-63826-z
25 days ago
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reposted by
Neuroengineering
Russ Poldrack
26 days ago
OpenNeuro
@openneuro.bsky.social
just hit a huge milestone: 1500 datasets! Congrats to the team on making this project so successful over the last 7 years.
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🧠⚡️ Can transcranial alternating current stimulation (tACS) truly rhythmically modulate brain activity in humans? More than 30 labs are joining forces in the tACS Challenge, a global effort to test one of brain stimulation's biggest questions. 🧵1/5
26 days ago
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Precision Neuroscience published their high-density ECoG in Nature Biomed. Eng. The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution.
#neuroskyence
@precisionneuro.bsky.social
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Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation - Nature Biomedical Engineering
A 1,024-channel microelectrode array is delivered to the brain cortex via a minimally invasive incision in the skull and dura, and allows recording, stimulation and neural decoding across large portions of the brain in porcine models and human neurosurgical patients.
https://www.nature.com/articles/s41551-025-01501-w
about 1 month ago
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Can we combine neural data across individuals to improve speech BCIs? A recent study used transfer learning on distributed iEEG recordings to enhance speech decoding. By learning shared latent manifolds, their cross-subject model outperformed individual models in a speech motor task.
#neuroskyence
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Transfer learning via distributed brain recordings enables reliable speech decoding - Nature Communications
Speech brain-computer interfaces face challenges scaling across individuals with different brain organization. Using minimally invasive recordings from 25 patients, the authors developed transfer learning methods that enable robust speech decoding even with incomplete brain coverage.
https://www.nature.com/articles/s41467-025-63825-0
about 1 month ago
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Neuropixel's newest ultra-high density probe enables larger neuronal yield (up to 2x), with over 6000 recording channels.
#neuroskyence
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about 1 month ago
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Optimizing stimulation patterns for visual implants 👁️ Check out
@mbeyeler.bsky.social
's recent study on using spiking activity to adapt stimulation parameters for more stable and reliable perception
#neuroskyence
#bci
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about 1 month ago
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How does intracortical microstimulation (ICMS) affect the brain? ICMS affects both vascular and immune responses. Higher currents increase blood-brain barrier leakage, letting substances enter surrounding tissue. Soon after, microglia activate and cluster around highly active regions
#neuroskyence
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Intracortical Microstimulation Induces Rapid Microglia Process Convergence
Intracortical microstimulation (ICMS) has the potential to restore vision and hearing by stimulating relevant cortical regions in both animals and hum…
https://www.sciencedirect.com/science/article/pii/S0142961225006519
about 1 month ago
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Better neural decoding using connectomics and emotional states? Check out
@julianneumann.bsky.social
newest study in Nature Biomed. Eng!
#neuroskyence
#bci
#compneurosky
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about 1 month ago
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How does the body regulate blood pressure after SCI? Scientists mapped the precise nerve circuits causing dangerous spikes in mice, rats, and humans. By stimulating these circuits with epidural electrical stimulation, they activated a competing pathway that stabilized blood pressure.
#neuroskyence
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A neuronal architecture underlying autonomic dysreflexia - Nature
The neuronal architecture that develops after spinal cord injury and causes autonomic dysreflexia is uncovered.
https://www.nature.com/articles/s41586-025-09487-w
about 2 months ago
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Blood pressure control after SCI has been challenging — until now. Swiss and Canadian researchers developed an implantable system that epidurally stimulates three thoracic segments, triggering a strong pressor response and rapidly reducing hypotensive symptoms.
#neuroskyence
#sci
#onward
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An implantable system to restore hemodynamic stability after spinal cord injury - Nature Medicine
A purpose-built implantable system based on biomimetic epidural electrical stimulation of the spinal cord reduces the severity of hypotensive complications in people with spinal cord injury and improv...
https://www.nature.com/articles/s41591-025-03614-w
about 2 months ago
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How far can intravascular electrodes reach? Scientists miniaturized stentrode-like electrodes to access small, deep cortical veins. Their probe goes beyond large vessels used by Synchron, enabling recordings from hand and speech regions with ECoG-level quality.
#neuroskyence
#bci
#synchron
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Microendovascular Neural Recording from Cortical and Deep Vessels with High Precision and Minimal Invasiveness
Intravascular electroencephalography (ivEEG) using micro-intravascular electrodes was developed. Cortical-vein ivEEG showed a higher signal-to-noise ratio and finer spatial resolution of somatosensor....
https://advanced.onlinelibrary.wiley.com/doi/10.1002/aisy.202500487
about 2 months ago
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Might focused ultrasound one day replace DBS? UK Scientists built a 256-panel focused ultrasound helmet that can precisely target deep brain regions. Using theta-burst TUS, they stimulated the LGN and found visual cortex activity with effects lasting up to 40 minutes.
#neuroskyence
#ultrasound
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Ultrasound system for precise neuromodulation of human deep brain circuits - Nature Communications
Modulating deep brain structure can lead to therapies for neurological conditions. Here, the authors show a transcranial ultrasound stimulation (TUS) system featuring a 256-element helmet-shaped trans...
https://www.nature.com/articles/s41467-025-63020-1
about 2 months ago
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about 2 months ago
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#neuroskyence
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about 2 months ago
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Neuralink update 🧠 • 2 new patients implanted in Canada, marking first trials outside the US • US patent office rejects ‘telepathy’ and ‘telekinesis’ trademarks, as they were previously claimed by a lucid dreaming startup
#neuroskyence
#bci
#neuralink
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Neuralink’s Bid to Trademark ‘Telepathy’ and ‘Telekinesis’ Faces Legal Issues
The brain implant company cofounded by Elon Musk filed to trademark the product names Telepathy and Telekinesis. But it turns out that another person had already filed to trademark those names.
https://www.wired.com/story/uspto-denies-neuralinks-applications-for-telepathy-telekinesis-marks/
2 months ago
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3 months ago
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A password protected inner speech BCI 🧠 Researchers showed that inner speech can be decoded from motor cortex, offering a less fatiguing alternative to attempted speech. To ensure user privacy, the system only activated when participants said 'chitty-chitty-bang-bang'.
#neuroskyence
#neuro
#bci
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Inner speech in motor cortex and implications for speech neuroprostheses
Inner speech is robustly represented in the motor cortex and can be decoded in real time to restore communication to people with paralysis. Unintentional decoding of private inner speech can be preven...
https://www.cell.com/cell/fulltext/S0092-8674(25)00681-6
3 months ago
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Sam Altman just got into BCI by backing Merge Labs 🧠 - Valued at $850M after a $250M raise - Developing high-performance, non-invasive brain-computer interfaces - Their bet: focused ultrasound + neuronal gene editing (sonogenetics)
#neuroskyence
#neuropapers
#openAI
#BCI
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Sam Altman’s new startup wants to merge machines and humans
Merge Labs is a new Neuralink rival developing brain-computer interfaces.
https://www.theverge.com/news/758577/sam-altman-merge-labs-neuralink-rival
3 months ago
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German BCI startup CorTec announces first in-human use of a fully implanted ECoG grid 🇩🇪🧠 The Seattle-based trial, led by Jeffrey Ojemann (U Washington) and Steven Cramer (UCLA), tests if cortical stimulation can aid upper limb recovery of stroke patients.
#neuroskyence
#neuropapers
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CorTec Announces Neurotech Milestone: First Human Implantation of a Brain-Computer Interface made in Germany | CorTec | Thinking ahead – Innovation in Neurotechnology
Marking a milestone for CorTec. The First implantation of the Brain Interchange System took place at Harborview Medical Center (Seattle).
https://cortec-neuro.com/first-human-implantation-of-a-bci-made-in-germany/
3 months ago
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Neuralink update 🧠 - P8 and P9 have been implanted within one day - 20 participants are expected by the end of 2025 - Bloomberg estimates $1B revenue by 2031, generously assuming 20k implantees
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Neuralink Sees $1 Billion of Revenue by 2031 in Vast Expansion
Elon Musk’s brain implant company Neuralink Corp. expects to put its chips in 20,000 people a year by 2031, generating at least $1 billion in annual revenue, in a major ramp up of its work to treat di...
https://www.bloomberg.com/news/articles/2025-07-23/neuralink-sees-1-billion-of-revenue-by-2031-in-vast-expansion
4 months ago
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Meta published their EMG wristband in Nature 📄 They developed a non-invasive neuromotor interface using a wrist-worn device for decoding gestures and handwriting. Its performance scales with the number of participants and can be further enhanced through personalized user tuning.
#Neuropapers
#CTRL
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A generic non-invasive neuromotor interface for human-computer interaction - Nature
A high-bandwidth neuromotor interface offers performant out-of-the-box generalization across people.
https://www.nature.com/articles/s41586-025-09255-w
4 months ago
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Nudge just secured $100M Series A funding 💰 The company is developing whole-brain ultrasound interfaces to target psychiatric and cognitive disorders. They plan to enhance the Nudge Zero and validate its impact through clinical studies.
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Announcing Nudge's $100M Series A Fundraise
Nudge - Whole-brain interfaces for everyday life
https://nudge.com/blog/series-a/
4 months ago
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Great to see more BCI developments in asia!
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4 months ago
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Ripples segment experiences during natural viewing Scientists observed hippocampal ripples peak at event boundaries of movie scenes. Meanwhile, ripples in temporal cortex rise within events and predict which moments will be remembered. These fast oscillations seem to support memory formation.
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Movie-watching evokes ripple-like activity within events and at event boundaries - Nature Communications
The neural processes involved in memory formation for realistic experiences remain poorly understood. Here, the authors found that ripple-like activity in the human hippocampus and neocortex tracks ke...
https://www.nature.com/articles/s41467-025-60788-0
4 months ago
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How do central brain areas work together to create movement? New work from the Courtine lab showed that premotor areas encode movement plans (the why), while primary motor and somatosensory cortices handle execution (the how). Control flows through low-dimensional subspaces from plan to action.
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Regional specialization of movement encoding across the primate sensorimotor cortex - Nature Communications
How the cortex generates movement to achieve different tasks remains poorly understood. Here the authors show that the cortex serializes motor control by first performing task-specific computations in...
https://www.nature.com/articles/s41467-025-61172-8
4 months ago
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🧠🕹️ Neuralink just shared an update: - 7 participants implanted (SCI & ALS) - Hand-knob area for now, speech motor cortex later this year - First vision BCI in 2026 with deeper threads (5cm/2inch) - 10k channels in 2027 - Full-brain coverage in 2028 for psychiatric diseases, epilepsy and pain
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Neuralink Update, Summer 2025
YouTube video by Neuralink
https://youtu.be/FASMejN_5gs?si=AlPA1FOJQo8Ww6qf
4 months ago
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Scientists invented contact lenses that let you see infrared light 💡 These special lenses use embedded nanoparticles to shift near-infrared light into the visible spectrum. With them, people can detect shapes, flashes, and even color patterns - even with their eyes closed.
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Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses
Based on the principle of refractive index matching, highly transparent upconversion contact lenses (UCLs) with a high concentration of upconversion nanoparticles (UCNPs) were developed. These lenses ...
https://www.cell.com/cell/abstract/S0092-8674(25)00454-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867425004544%3Fshowall%3Dtrue
5 months ago
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Neuropixel NHP 1.0 has just been published in Nature Neuroscience. The new probe, designed specifically for non-human primates, features an electrode array with roughly 4000 sites over 4.5 mm, 384 of which can be recorded simultaneously. The study details its design, fabrication, and performance.
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Large-scale high-density brain-wide neural recording in nonhuman primates - Nature Neuroscience
Neuropixels 1.0 NHP is a 45-mm, high-density silicon probe capable of recording large numbers of neurons with single-neuron resolution from most areas in a macaque’s brain.
https://www.nature.com/articles/s41593-025-01976-5
5 months ago
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Stavisky & Brandman published their speech prosthesis in Nature 🗣️🧠 They demonstrate streaming speech synthesis with a latency of only 50 ms in a man with ALS. The system captures paralinguistic features like pitch, intonation, and word emphasis - bringing BCI communication closer to natural speech.
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An instantaneous voice-synthesis neuroprosthesis - Nature
A brain-to-voice neuroprosthesis enables a man with amyotrophic lateral sclerosis to synthesize his voice in real time by decoding neural activity, demonstrating the potential of brain–computer interf...
https://www.nature.com/articles/s41586-025-09127-3
5 months ago
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Great to see an invasive BCI network developing in Europe!
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5 months ago
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How does the brain find the right words? Scientists identified two key language networks through 48 ECoG recordings. Semantic meaning is integrated in the IFG and MFG, while speech movements are planned in the IFG and precentral gyrus. Both networks work together to support word retrieval.
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A left-lateralized dorsolateral prefrontal network for naming
Yu et al. dissociate two left-lateralized language networks leading up to word retrieval using electrocorticography in 48 patients: a semantic processing network spanning MFG and IFG, which encodes wo...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00448-6
5 months ago
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What if you could implant electrodes in the developing brain, so it grows around them? Researchers at Harvard implanted Axoft’s soft bioelectronics onto the neural plate — an early sheet of stem cells. As the brain grows and folds, the electronics became embedded within it.
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Brain implantation of soft bioelectronics via embryonic development - Nature
A soft mesh microelectrode array can seamlessly integrate in developing brains, enabling long-term, stable mapping of how single-neuron activity and population dynamics emerge and evolve during brain ...
https://www.nature.com/articles/s41586-025-09106-8
5 months ago
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Paradromics just completed its first in-human clinical trial. The procedure took place at the university of michigan in collaboration with
@matthewwillsey.bsky.social
. An epilepsy patient undergoing surgery was implanted with the device to prove safety.
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Neuralink competitor Paradromics completes first human implant
The procedure took place at the University of Michigan with a patient who was already undergoing neurosurgery to treat epilepsy.
https://www.cnbc.com/2025/06/02/neuralink-paradromics-human-implant.html
5 months ago
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Meet us at the
#BCI25
meeting by the
@bcisociety.bsky.social
in Banff, Canada, this week! 🧠 We have a poster on tuesday afternoon and are looking forward to connect with new and familiar colleagues!
5 months ago
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Emergence of language in the developing brain 🧠🗣️ Scientists recorded intracranial activity from 46 children aged 2–18 as they listened to The Little Prince. Toddlers showed phonetic encoding in the superior temporal gyrus, while word-level meaning emerged later in associative cortices.
6 months ago
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ONWARD Medical implanted two more spinal cord injury patients with their ARC-BCI system. A 48-year-old man and a 37-year-old woman received the ECoG implants in Lausanne earlier this year - totaling five participants overall for the study.
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https://ir.onwd.com/static-files/f7b93ad3-5e98-4228-9bfb-bfc1b78f15ff
6 months ago
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