New hypothesis paper: the anterior–posterior (A–P) axis in early embryos may do more than pattern the body—it could create gradients of genome stability, with anterior regions more error-prone and posterior regions protected by morphogen signaling. 🧬 onlinelibrary.wiley.com/doi/10.1002/...

🚨 PhD opportunity Interested in stem cells, mammalian development, and omics? The Migeotte & De Jaime-Soguero labs are recruiting a PhD student with bioinformatics background to work on embryonic and extraembryonic development. 🗓 Deadline April 2026 👇 Details below www.iribhm.org/open-positio...

🚨 Paper alert! The final version of our latest manuscript is published. We are excited to share this new resource for the zebrafish community and beyond: doi.org/10.7554/eLif... Congratulations to all authors! 🥳

Beautiful, thorough, personal in places, memoir of John Gurdon from Eddy de Robertis, disciple and friend. Å #MustRead about a generation and a time from which we have moved on but that laid the foundation for contemporary biology. www.sciencedirect.com/science/arti...

Cellular signaling (BMP/SMAD) at the helm of chromosomal instability in cancer, similar as what we described during development and lineage specification. Congrats to our collaborators at the Bastians lab.

‼️‼️📢📢 Job Alert! Our lab at @iribhm.bsky.social - @ulbruxelles.bsky.social is seeking for a PhD student to work on the proteostasis of early mammalian development using stem cell models and the embryo. If you are enthusiastic about cell and dev biology, please apply!

Excited to present our work tomorrow online at Social DNAing series. 18.00PM CEST time following the link below.

The modularity of the mammalian #embryo in display. Controlled assembly of classic #gastruloids and uncommitted precursors in #hypoxia, patterns the AP axis www.biorxiv.org/content/10.1... Beautiful & insightful from @bulutkarslioglu.bsky.social‬ group. Building models to learn and learning.

Crick researchers have developed a new stem cell model of the mature amniotic sac development. The team is now exploring the potential for using these new 3D models in clinical applications, such as cornea reconstruction and treating ulcers. www.crick.ac.uk/news/2025-05...

Join us tomorrow for our next seminar: 🗓️ Thursday, May 08 ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

Looking forward to giving this talk next week!

Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...

Last few months have been of change. I finished my postdoc at @cosheidelberg.bsky.social and moved to Belgium to begin my research group at @iribhm.bsky.social. I will reflect here my thoughts about the last years experience.

In this Review, @eliananehme.bsky.social, @amiteshp.bsky.social, Isabelle Migeotte and @pasquelab.bsky.social give an overview of the embryonic origin and function of extra-embryonic mesoderm in vertebrates from in vivo studies. journals.biologists.com/dev/article/...

Do you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response

SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.   Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...

Design of a STING fluorescent real time biosensor. Tour de force of my colleague #Steve under Sergio @acebronsp.bsky.social supervision. 👏👏👏

Novel insights on cellular signaling regulation of DNA replicative dynamics. BMP signaling not only prevents from replicative stress in pluripotency, as we described recently (www.nature.com/articles/s41...) but also drives regeneration through same mechanisms. www.nature.com/articles/s41...

Surprisingly we find that as few as 2 starting p53KO cells will compete in an environment of @300 WT cells. Also, see an input for BMP & Wnt signalling that mirrors work on the control of chromosomal segregation in stem cells www.nature.com/articles/s41...

Great work on cell competition during mammalian gastrulation. It aligns with our observations on chromosome stability-driven by morphogens and open further questions on the relation of cellular fitness and genome integrity. Congrats!

Great city, great environment and cool projects (including stem cell modelling, development, homeostasis and cancer biology). Have a look to the research groups offer and do not hesitate to apply!

Great opportunity for a PhD in Brussels. Outstanding mentor and project addressing bottlenecks in human development

⚠️📢 Few weeks to close the call. If you love cell & devbio, and are interested on doing a PhD in stress resilisence, please APPLY!

Gracias a Pilar Perla y @heraldo.es por la difusión de nuestro trabajo en el lab de Sergio Acebrón @acebronsp.bsky.social y mi opinión sobre la investigación básica en mi tierra, Aragón. www.heraldo.es/noticias/ara...

Registration is open for the 12th Advances in Stem Cell Biology Course #ASCBcourse at the @pasteur.fr Hands-on training in different models, embryonic stem cells, iPS cells and much more on #StemCells. 🕘June23-July04, 2025 👉https://qrfy.io/VEcoKQpGfV

🚨 🚨 Job Alert! I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!

Applications open for a new cohort of @dev-journal.bsky.social *Pathway to Independence* fellows Know a #devbio post-doc about to enter the academic job market? Would they benefit from a little support & mentoring? Spread the word Deadline 31 Jan 2025 journals.biologists.com/dev/pages/pi...

What a day! An honour to present our work next to these giants and the dynamic belgian stem cell researchers. Great to be back!

It was a fantastic edition of the 8th Meeting of the Belgian Society for Stem Cell Research in Brussels with stellar speakers including Susana de Sousa Lopes, Jacob Hanna, Florian Merkle, Anchel de Jaime-Soguero and many more. Thank you to all participants. #BeSSCR #StemCells

🚨 🚨 Job Alert! I am currently opening my research lab at @iribhm.bsky.social @ulbruxelles.bsky.social in Belgium and I am seeking for an enthusiastic PhD candiate to study cellular stress across mammalian development and lineage specification! If you are interested, info below. Please RT!

We recently uncovered that morphogenetic signals not only read our blueprints, but are key to maintain them, particularly in stem cells. Joint effort of numerous collaborations and the lead of Prof. Sergio Acebrón at @cosheidelberg.bsky.social www.nature.com/articles/s41...