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Paper from me, Michelle Curtis,
@soumya-boston.bsky.social
and co out now in
@natmethods.nature.com
! We now call it starCAT instead of *CAT but the strategy is the same: Build a catalog of ~50 interpretable T cell gene expression programs + use them to interpret new data
nature.com/articles/s41...
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Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions - Nature Methods
TCAT is a pipeline that can simultaneously capture gene expression programs related to T cell subsets and activation states for accurate T cell characterization.
https://nature.com/articles/s41592-025-02793-1
2 months ago
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