Single-centre (@petermaccc.bsky.social) real-world data on #BiliaryTractCancer: 1st line gem/cis+ICI yields outcomes comparable to pivotal trials. ECOG & albumin predict survival. #HER2 amp = worse OS; dMMR & #BRCA = trend toward improved OS. Study highlights importance of molecular profiling.

Optimistic bias related #Adherence of metastatic #BreastCancer patients to oral anticancer treatments: negative association between adherence rate and self-perception of treatment adherence. Personality matters: conscientiousness = risk awareness; extraversion = overconfidence. #Oncology

Higher state/local social + public health spending = fewer poverty-linked cancers. Top-spending states saw ~8% lower incidence and ~9% lower mortality. Investing upstream can cut cancer burden and narrow inequities. #Oncology #PublicHealth #SDOH #CancerPrevention #HealthEquity

A cross-sectional survey of 198 #BreastCancer specialists across #Europe reports a strong endorsement of shared decision-making, but patchy uptake. Female physicians favour participatory styles. Digital #DecisionAids still underused compared to paper ones. #Communication #Oncology #SDM

Comprehensive review published in Cancer Control synthesizing #ClinicalTrials data on #OncolyticViruses (OVs) spanning 2013-2024. Provides an in-depth examination of OVs, highlighting their advancement from investigational modalities to clinical implementation. #ImmunoOncology #Virotherapy

BRCA1/2-mutant early #BreastCancer: review urges region-tailored testing in Latin America, MRI-first screening, and shared surgical decision making. Neo-adjuvant platinum can raise pCR, while adjuvant olaparib improves OS. #BRCA #TNBC #PARPi #Latam

A Preliminary Prospective Study on the Association of Polymorphisms in BDNF, ARRB2 and KCNJ6 and Response to Fentanyl for Pain Management in Advanced Cancer @cancer-control.bsky.social @journals.sagepub.com journals.sagepub.com/doi/10.1177/... #cancercare #dosingguidelines #pharmacogenomics

Is Site of Radiation Therapy Associated With Pathologic Complete Response in Patients With Locally Advanced Esophageal Cancer? @cancer-control.bsky.social @journals.sagepub.com journals.sagepub.com/doi/10.1177/... #radiationoncology #radiotherapy #cancercare #cancertreatment #openaccess

#EarlyOnsetCRC (<50) is rising & distinct: more left-sided/advanced disease, higher MSI-H/CIMP, and unique genomic/microbiome profiles. Action: lower screening age + risk-based, noninvasive, multi-omics/microbiome-guided care. #ColorectalCancer #CRC #Screening #PrecisionOncology

Oncology visits with Black patients & non-Black physicians: higher physician #ImplicitBias → more nonverbal synchrony; higher patient trust → more patient-led synchrony. Takeaway: pair bias-mitigation with workflow/communication training to strengthen equitable care. #Oncology #PatientCommunication

Density and maturity of Tertiary Lymphoid Structures (TLS) may predict clinical outcome in invasive #LungCancer. In a 750 pt cohort, high intratumoral TLS density independently predicted better OS, while higher TLS maturation predicted worse outcomes. TLS features may sharpen risk stratification.

Analysis of #GBD2021 (204 countries) data reveals that #PancreaticCancer deaths tied to high #BMI have surged since 1990. Women still higher burden, but men rising faster, esp. ages 20–49 & low-SDI regions. #Obesity prevention + equity-focused policy needed. #GlobalHealth

Homelessness increases #HBV/#HCV risk. Community outreach in housing + drop-in sites linked ~2,000 Texans to care (≈2/3 needed services). Targeting engagement sites based on specific goals can help practitioners maximize outreach to high-need populations. #HealthEquity #PublicHealth

Pilot, co-designed brief decision aid for #ColorectalCancer #Screening, targeted to ages 75–85 with limited #HealthLiteracy. 20→8 pages; understandability 44→75%, actionability 29→100%, clarity 71→~88. Supports #SharedDecisionMaking; RCT next. Study out in Cancer Control. #CancerScreening #CRC

Early Feedback for the Development of a Novel Brief Colon Cancer Screening Decision Aid for Adults ≥75 years at Risk for Limited Health Literacy: A Pilot Study @cancer-control.bsky.social @journals.sagepub.com journals.sagepub.com/doi/10.1177/... #patientcare #healthcare #oncosky #oncology

A 4-week pilot in breast/colorectal cancer survivors testing continuous glucose monitoring (#CGM) + Fitbit + tailored texts was acceptable & shifted exercise readiness into action/maintenance. CGM biofeedback may help drive #PhysicalActivity; larger trials needed. #DigitalHealth #CancerSurvivorship

In a survey of 1,357 Oregonians, Asian/Pacific Islander & unemployed/disabled adults reported more negative cancer beliefs & less confidence finding trustworthy info. Study highlight need for targeted, multilingual outreach via trusted channels to boost #CancerScreening & #CancerEquity #PublicHealth

A pre-surgery prediction model using ultrasound, routine pathology, and simple blood tests, accurately flags axillary lymph-node spread in early #BreastCancer pts. In 287 pts it showed high accuracy and real clinical utility, supporting fewer unnecessary invasive procedures. #PrecisionOncology

A routine blood score (SII) predicts patients with advanced non-small cell #LungCancer who benefit from PD-1/PD-L1 therapy. Low SII = higher response & longer PFS/OS, outperforming NLR/PLR. Data support using SII to guide selection & monitoring. #NSCLC #Immunotherapy #Biomarkers

Triple-mutated #AML (NPM1+FLT3-ITD+DNMT3A) is a highly aggressive subset. In 165 pts it comprised 6.7%, showed monocytic features, and had ~4-mo median survival despite similar remission. Low GNG4 expression linked to worse survival → potential prognostic #biomarker. #Leukemia #PrecisionOncology

A simple pre-treatment blood test score (pretreatment pan-immune-inflammation value) powerfully predicted #RectalCancer patients who would respond better to neoadjuvant treatment. Patients with a low score did much better, pointing to more personalised, organ-sparing care. #Oncology #Biomarkers

After limb-sparing surgery for lower-extremity soft tissue #sarcoma, adjuvant conventional #radiotherapy (RT) delivered better function & #QualityOfLife than hypofractionated neoadjuvant RT, with similar oncologic control. Data support prioritizing post-op RT. #RadiationOncology

3-trial meta-analysis (n=1,254): Cabozantinib + atezolizumab didn’t improve ORR/DCR vs cabozantinib alone, but lowered several treatment-related adverse events (diarrhea, nausea, vomiting, hypokalemia). The combo may be a useful regimen for patients who cannot tolerate cabozantinib monotherapy.

Electronic health record study maps distinct comorbidity patterns in early-onset #LiverCancer. Findings support race/ethnicity-tailored screening and targeted interventions to reduce disparities. #HealthEquity #CancerResearch #MachineLearning

Cancer Control study in ~30k #Pennsylvania teens reveals that #HPV #Vaccination still lags after COVID. Only ~67% start by age 17. Younger cohorts start earlier, but gains have plateaued. Earlier recommendations starting at age 9 & targeted outreach may accelerate #CancerPrevention.

Qualitative study in #RareCancers #Genomics surfaces 7 drivers of participant engagement and turns them into actionable communication & operations steps, helping teams boost recruitment/retention, build trust, and accelerate discovery. #Oncology #AYAOncology #PatientEngagement #Sarcoma

A recent review published in Cancer Control proposes using the 1978 Alma Ata principles to redesign global cancer care—integrating oncology into strong primary health systems to boost prevention, early detection & equity, ensuring advances reach all, regardless of geography or income. #HealthEquity

A new Cancer Control scoping review finds optimal cancer referrals from #PrimaryCare should include detailed symptoms, relevant tests/exams, & the GP’s rationale. Clearer referrals can speed diagnosis & cut delays. #Oncology #CancerDiagnosis #EarlyDetection #HealthcareQuality #NHSEngland

Supporting Participant Engagement in Cancer Genomics Research in Rare Cancers: A Qualitative Study of Patients, Caregivers, and Advocates @cancer-control.bsky.social @journals.sagepub.com journals.sagepub.com/doi/10.1177/... #sarcoma #cancerresearch #oncology #medsky #openaccess

#CancerCare in #Georgia imposes a heavy financial burden, with significant out-of-pocket costs for most patients. ~75% of patients face major financial strain even with universal health coverage, & many take loans, mainly for diagnostics. #FinancialToxicity #HealthEquity #LMIC

#COVID19 led to a sustained drop in #CRC screening in #Israel, especially among Arab and Orthodox Jewish groups. Findings could have implications for early detection and treatment of CRC within these two specific demographic groups. #ColorectalCancer #HealthEquity #COVID19Impact

Using e-health tools boosts cancer screening among older adults in the #UnitedStates, by reducing cancer fatalism and increasing cancer worry. Empowering digital health access can drive prevention. #CancerScreening #eHealth #DigitalHealth #CancerPrevention #BehavioralOncology

Recent Cancer Control review highlighting how emerging therapies (PARP inhibitors, #immunotherapy, gene editing, nanotech) are reshaping #GynecologicOncology. Promising advances for more effective, personalized treatment. #CancerResearch #PrecisionMedicine #OncologyInnovation

New nomogram predicts cancer-specific survival in stage I vulvar squamous cell carcinoma (VSCC) with greater accuracy. A step forward in personalized care for early VSCC. #VSCC #GynecologicOncology #CancerSurvival #Nomogram #PrecisionMedicine

New ensemble RBE modeling improves proton therapy safety near the brainstem by better estimating biological dose. A key step toward more precise, risk-aware treatment planning. #ProtonTherapy #RBE #RadiationOncology #MedicalPhysics #BrainstemSafety

Young adults of color face higher risks in early-onset #ColorectalCancer—more late-stage diagnoses, aggressive tumors, and worse survival. Prioritizing prevention strategies and enhancing access to screening for racial minorities and the 20-29 age group is warranted. #EOCRC #HealthEquity #Oncology

LRPPRC is emerging as a pan-cancer biomarker linked to poor prognosis, immune evasion & drug resistance. #CancerBiomarkers #LRPPRC #PanCancer #PrecisionMedicine #Immunotherapy

#Radiotherapy doesn’t boost survival in low-grade endometrial stromal #sarcoma. Primary treatment remains surgical, with careful consideration of fertility preservation in younger women, and individualized management for advanced cases. #GynecologicOncology #CancerCare #PrecisionMedicine

New #ML tool predicts early mortality in lung adenosquamous carcinoma with high accuracy (AUC 0.84). Built on SEER data, and deployed as a web app to aid personalized care. A useful tool for guiding decisions in rare lung cancers. #LungCancer #MachineLearning #PrecisionOncology

Global soft tissue sarcoma cases & deaths rose from 1990–2019, driven by aging populations, despite stable age-adjusted rates. Findings highlight the need for better surveillance & early detection in LMICs. #Sarcoma #GlobalHealth #Oncology #CancerBurden

New Cancer Control study reports that adding mirogabalin to low-dose duloxetine significantly eased taxane-induced neuropathy in lung cancer patients. A promising combination for tackling CIPN where monotherapy falls short. #CIPN #LungCancer #SupportiveCare #Oncology #NeuropathicPain

New Cancer Control study reports that CT-based radiomics + clinical data = 96% AUC in distinguishing SCLC from NSCLC. Including peritumoral features boosts accuracy & guides surgery. #Radiomics #LungCancer #SCLC #AIinMedicine #Oncology

New data from #Pakistan show ~75% of colorectal cancer cases occur under the age of 60. Early-onset #CRC is rising fast. There is an urgent need for early screening & tailored care in #LMICs. #ColorectalCancer #EOCRC #GlobalHealth #CancerScreening #Oncology

Perspective on the use of militaristic metaphors in cancer care. Two key issues overlooked: the dual-use military tech in medicine, & the voices of those with war experience. Time to shift toward respectful, inclusive language. #CancerDiscourse #HealthCommunication #OncologyEthics #ScienceAndSociety

Validated in #Taiwan: The CARG model effectively predicts #chemo toxicity and survival in older adults with #cancer. Anemia, falls, and poor mobility are identified as key risk factors, supporting personalized, safer oncology care. #GeriatricOncology #CARGModel #CancerCare #PrecisionMedicine

#Osimertinib shows high efficacy in EGFR-mutant #NSCLC with brain metastases—91.9% CNS response & 35.2 mo OS. Adding radiotherapy didn't boost outcomes but raised toxicity. Real-world data from #Vietnam support deferring radiation in select patients. #LungCancer #Cancer #Oncology #EGFR

New Cancer Control review highlights how #Adipokines and adipose-derived miRNAs shape the #BreastCancer tumor microenvironment, driving growth, immune evasion, and therapy resistance. Promising new targets for treatment and diagnostics emerge. #Oncology #TME

New Cancer Control study reveals deep inequities in hereditary cancer risk assessment. Excluded communities face systemic barriers & underrepresentation in genetic databases. Calls for anti-racist, community-driven reform in genomic research. #GenomicEquity #CancerDisparities #HealthEquity

New Cancer Control study finds major gaps in #SunSafety policies in #Texas schools. While most allow sunscreen, few offer shade or sun-protective clothing, especially in rural, low-income areas. Stronger policies are linked to more nurses & higher income. #SkinCancer #HealthEquity #Melanoma

Site-driven protocol changes helped w completion of this $ navig study. Addressing Challenges in Research Aimed at Reducing Financial Toxicity Among Cancer Patients & Caregivers: An Example From the CREDIT Study (@swog.org S1912CD), in @cancer-control.bsky.social journals.sagepub.com/doi/10.1177/...