The hallmarks of cancer immune evasion

We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded

The SONIA trial shows the utility of well-designed academic trials. But funding such studies is getting harder and harder. We need to work with industry to design smarter trials that don’t need further costly and lengthy trials to fill gaps www.nature.com/articles/d41... @oncoalert.bsky.social #bcsm

This is potentially very interesting data but follow up is short at this point and would want to see an EFS/OS outcome. Does provide early signal and could be useful for those where steroids are contraindicated or problematic

⏰ Final call! 🧑‍🔬 Last week to apply for this fantastic opportunity to work with the exceptional @giampazolias.bsky.social at @cruk-mi.bsky.social. #TeamManchester To apply (deadline 1 Dec 2024): www.cruk.manchester.ac.uk/recruitment/...

Nice review! I’m sure we will have combination strategies in the clinic on the next few years but must balance efficacy with cost/side effect profiles

Yep quoting to keep the links!

Reassuring BUT short follow up at this time point

Interesting results, be nice to see these replicated in other eTNBC IO trials. Also to explore links with irAEs

Anecdotally, seeing an awful lot of younger patients with TNBC coming through MDT. Is anyone else seeing this?

I’m excited to see data at #SABCS but I’m also mindful that we are adding more and more to treatments and feel like we’re reaching the point that we need to start trying smarter patient selection to prevent harm @oncoalert.bsky.social #oncsky

We really need some better biomarkers for immunotherapy toxicity…. Im worried we’re storing up psome big issues down the line

Well this seems rather pleasant compared to… you know the other place