Jessica Beserra Felix, PhD
@jessicab-felix.bsky.social
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Adipose tissue metabolism @BaylorCollegeofMedicine . Current postdoc @GladstoneInstitutes
reposted by
Jessica Beserra Felix, PhD
Nature Metabolism
4 months ago
RESEARCH | 🧪
@jessicab-felix.bsky.social
, S Hartig et al
@bcmfromthelabs.bsky.social
N-acetylaspartate from fat cells regulates postprandial body temperature
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N-acetylaspartate from fat cells regulates postprandial body temperature - Nature Metabolism
Aspartoacylase expression in white adipose tissue regulates circulating levels of N-acetylaspartate, which in turn modulates plasma pyrimidine levels and regulates postprandial body temperature.
https://bit.ly/4mlfzj1
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reposted by
Jessica Beserra Felix, PhD
Nature Metabolism
6 months ago
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N-acetylaspartate from fat cells regulates postprandial body temperature
Nature Metabolism, Published online: 23 July 2025; doi:10.1038/s42255-025-01334-6Aspartoacylase expression in white adipose tissue regulates circulating levels of N-acetylaspartate, which in turn modulates plasma pyrimidine levels and regulates postprandial body temperature.
https://bit.ly/3UyfgWp
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reposted by
Jessica Beserra Felix, PhD
Nature Metabolism
6 months ago
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Much ado about NAA-thing
Nature Metabolism, Published online: 23 July 2025; doi:10.1038/s42255-025-01327-5A recent study in Nature Metabolism by Felix et al. reveals that the breakdown of N-acetylaspartate (NAA) by the enzyme aspartoacylase (encoded by Aspa) in adipocytes has a crucial role in regulating circulating NAA levels, maintaining systemic glucose homeostasis and controlling postprandial body temperature.
https://bit.ly/40zBXx4
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It's been a long time coming but my PhD paper is finally published. Check it out!
@naturemetabolism.bsky.social
urldefense.proofpoint.com/v2/url?u=htt...
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N-acetylaspartate from fat cells regulates postprandial body temperature
Nature Metabolism - Aspartoacylase expression in white adipose tissue regulates circulating levels of N-acetylaspartate, which in turn modulates plasma pyrimidine levels and regulates postprandial...
https://urldefense.proofpoint.com/v2/url?u=https-3A__rdcu.be_ext7x&d=DwMFAg&c=ZQs-KZ8oxEw0p81sqgiaRA&r=FFzy6GBNKOnNTCvonS84uw&m=Zp8v8WabP1nGFeGqiLsdbZAGEvD6IcdGqnZ1_yNq3f9MUEcuuV9niyeSP2knFCv-&s=3LC4LD66x4YLPKQJH-dbQ0AEcwlXX19ixWYVRrSRQV8&e=
6 months ago
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At the Bay Area Aging Meeting today. Excited to hear some interesting science
8 months ago
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reposted by
Jessica Beserra Felix, PhD
Nature Metabolism
8 months ago
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Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution
Nature Metabolism, Published online: 13 May 2025; doi:10.1038/s42255-025-01296-9In this Review, the authors present a roadmap towards achieving consensus on development, analysis and interpretation of single-cell transcriptomics data in adipose tissue, including discussion of roadblocks, best practices and ideal cell-type markers for annotation of adipose tissue cell types in mice and humans.
https://bit.ly/4kgyWsT
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reposted by
Jessica Beserra Felix, PhD
Nature Metabolism
9 months ago
✨New issue! ✨ Check out the latest in #metabolism research. Read about #Metabolism in the #Brain, #Liver, #Gut, #AdiposeTissue, Protein #Lactylation, #IntermittentFasting - and other topics!
https://bit.ly/4cMZTlz
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New pre-print from the Jain Lab
www.biorxiv.org/content/10.1...
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Red Blood Cells Serve as a Primary Glucose Sink to Improve Glucose Tolerance at Altitude
High altitude conditions result in improved glucose tolerance and lower diabetes risk across species, yet the underlying physiological mechanism remains unclear. Using mouse models, we found that hypo...
https://www.biorxiv.org/content/10.1101/2025.04.24.650365v1
9 months ago
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Check out this new pre-print from the Hartig Lab! Interesting study on the role of adipose tissue in female mice
www.biorxiv.org/content/10.1...
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Beige fat appearance during lipoatrophy reveals trade-offs between metabolic homeostasis and female fertility
White adipose tissue (WAT) meets the energetic demands required for estrous cycle regularity, ovulation, and reproductive success in women. Here, we report WAT loss and subsequent female-specific comp...
https://www.biorxiv.org/content/10.1101/2025.04.21.649835v1
9 months ago
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reposted by
Jessica Beserra Felix, PhD
Ardem Patapoutian
12 months ago
It is indeed my understanding that most research institutions won't survive if this is implemented. I know I will contact my congress and senate members.
5calls.org
add a skeleton here at some point
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Looking for metabolism seminar recommendations and links to watch in 2025, preferably adipose tissue metabolism but also interested in other other aspects.
about 1 year ago
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