RIL-seq revealing sRNA-mediated phage-host dialogue! What a cool finding. Big congrats on the Molecular Cell paper!

How does a bacterial small RNA evolve new functions? Our new study reveals the stepwise evolutionary journey of UhpU, a 3′UTR-derived sRNA in E. coli and relatives. It evolved from a metabolically-focused regulator to one with expanded targets and biogenesis manner. www.pnas.org/doi/10.1073/...

Learning medical microbiology starts with Gram staining. 🔬 #Microbiology #MedStudent

Happy Chinese New Year！

Happy to share our latest work published in @pnas.org In collaboration with @yjchao.bsky.social , we uncovered an RNase III-processed sRNA, ManS, that orchestrates sialic acid metabolism in Salmonella enterica during gut colonization. Link: doi.org/10.1073/pnas...