Pleased to share that our latest paper is out now in NAR. We demonstrate that Pol η binds to and is a substrate of NEDD8. @ncmoreno.bsky.social @txelah.bsky.social @barneslab.bsky.social @irinabezsonova.bsky.social academic.oup.com/nar/article/...

Re-submitted manuscript awaiting decision *deep breaths*

Big day. Submitted a grant application in the morning - my fifth of the year 😵‍💫 - and resubmitted a paper in the evening

Can we imagine a future in which everyone can use their own language to write, assess & read science with the help of AI? Read this to see why we believe this is the future of academic publishing. Great collab with @bowkerl.bsky.social & Andrew Burton-Jones. #languagebarriers doi.org/10.1371/jour...

Pleased to share a new review article of ours on USP1 inhibitors. Thank you to Carlos Torrado and Tim Yap for inviting us to contribute www.sciencedirect.com/science/arti... Also, check out this excellent review on a similar topic from @hw1o9.bsky.social www.sciencedirect.com/science/arti...

Presented a poster today at a Dana-Farber symposium. I was asked by three people whether I am a PhD student. Glad to know I haven’t outwardly aged too much over the past decade.

According to the Office of Research Integrity, most drivers of research misconduct are due to work and/or life pressures. What a shock.

We are getting some good data!

Something amazing has happened at work. The building maintenance team has emptied and cleaned the fridges in our break room. The first time in living memory. And from now on they will be emptied once per month.

Today, the technician I am supervising said to me, in relation to our project, 'you know, this is actually pretty cool'. It made my day.

I am proud to share that after several years of on-again, off-again effort, I have finally finished Marcel Proust's 'In Search of Lost Time' (translation by Moncrieff and Kilmartin). It was one of the most incredible novels I have read, as well as one of the most difficult.

Today I assembled a new UV-C irradiation system. Parts include: a handheld UV lamp, a cardboard box, a polystyrene box, a piece of plywood, a step-up transformer and a UV dose metre. Stable output of 40 uW/cm2

Three days later and I can walk up and down stairs again.

I am pleased to share our latest preprint. In this work we show that the ubiquitin-binding domain of Pol eta interacts with NEDD8, and that this interaction is required for Pol eta mono-NEDDylation. Looking forward to having this work published-published. www.biorxiv.org/content/10.1...