Arwen Gao (@arwengao.bsky.social)

Thrilled to share our new study: “A lysosomal surveillance response to stress extends healthspan” Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan. www.nature.com/articles/s41... #lysosomes #LySR #aging

loading . . .

A lysosomal surveillance response to stress extends healthspan - Nature Cell Biology Li et al. uncover a lysosomal surveillance response whereby intestinal lumen deacidification induces a transcriptional programme that boosts lysosomal activity and improves protein aggregate clearance... https://www.nature.com/articles/s41556-025-01693-y

7 months ago