🧬 A big thank you to @andriygoychuk.bsky.social for his excellent presentation at the @prbb.org as part of the @barcelonacollaboratorium.com, and for taking the time to discuss different projects and ideas with us. #Collaboration #Collaboratorium @crg.eu @embl.org @helmholtzhzi.bsky.social

See our handy graphical abstract and article for free here: bit.ly/4vsl845

Check out our new work in Cell Systems @cp-cellsystems.bsky.social! Much of the biochemistry in the cell is organized by biomolecular condensates, but what mechanisms control the distribution of a given condensate throughout the cell? And is this mesoscale organization important for function?

Now out in Physical Review E: doi.org/10.1103/n662...

How are biomolecular condensates spatially organized? As example, we focus on fibrillar centers producing ribosomal RNA in the nucleolus. Disrupting this function disrupts their patterning, and disrupting patterning disrupts function. Out in Cell Systems: authors.elsevier.com/c/1nA3C8YyDf... (1/6)

How do active processes affect polymer conformations? I first began studying this question using linear response theory, and long thought that more general models could only be tackled with simulations. Turns out I was wrong: doi.org/10.48550/arX.... (1/8) #active #chromatin #folding #biophysics

Do different regions in the cell nucleus find each other by random motion or is there a directed component? In short: likely both. Below, I summarize a few predictions from a recently updated preprint from last June: doi.org/10.48550/arX.... (1/9) #biophysics #theory #active #chromatin #condensates

(1/3) I am setting up shop and will be hiring #PostDocs & #PhD students to join my independent theory group at the Helmholtz Centre for Infection Research (@helmholtzhzi.bsky.social‬) and the Lower Saxony Center for AI and Causal Methods in Medicine.