Luca Panconi (@lucapanconi.bsky.social)

📢 New preprint alert! Excited to share our novel method for simulating dynamic protein clustering. Here, we show how nanoscale clustering of proteins on the cell surface can modulate signal transduction, potentially converting analog signals into digital responses. www.biorxiv.org/content/10.1...

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Nanoscale protein clustering modulates the input-output response of cellular signalling pathways A key function of the plasma membrane is regulating signal transduction. Proteins involved in the transduction process play a signal-processing role; mapping an input (e.g. number of engaged receptors... https://www.biorxiv.org/content/10.1101/2025.03.13.642965v1.abstract