A health system wrecking ball: CMAJ editors stand unequivocally in support of our colleagues in Quebec in challenging this Bill 2. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252070

Curbing HIV/AIDS: "Now is the time to deliver on the promise of a made-in-Canada strategy to end HIV/AIDS." ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251245

Tuberculosis in Canada: "Canada has the resources required to reverse current trends and move toward TB elimination, but political prioritization and collective action are needed to use resources effectively." ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250722

Global funding for infectious disease control: "Canada’s reduced pledge to the Global Fund reflects short-sighted political thinking that fails to appreciate the complexity of global health threats and long-term health consequences." ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252036

Phenobarbital for severe alcohol withdrawal: Phenobarbital is an effective adjunctive medication for alcohol withdrawal. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250637

The Streptococcus pneumoniae serotype 9V is associated with increased antimicrobial resistance, is more prevalent in western Canada, and has increasing prevalence in elderly populations nationally than other pneumococcal serotypes. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251139

Access to pediatric trauma centers: Across 9 Canadian provinces, 1 in 4 children with major trauma did not receive care in a pediatric trauma centre. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250625

Reduced global funding for infectious diseases: what are the anticipated health impacts? CMAJ Volume 197, Issue 43, features new articles on global funding for infectious disease control; invasive pneumococcal disease; curbing HIV/AIDS, and more. ➡️ www.cmaj.ca/content/197/43

A family like this: A neonatologist reflects on the resilience and strength of a family supporting their newborn son with encephalopathy. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251156

Surgeons can achieve the goal of consistent quality and accountability by structuring single-entry referral networks so that the receiver of referrals is a group — within a hospital or a geographic area — and not an individual surgeon’s office. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251492

Bullous fixed drug eruption: Fixed drug eruption accounts for 14% to 22% of cutaneous adverse drug reactions, with ibuprofen among the most common causes. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251212

Chagas disease: Although people infected with Chagas disease can develop a febrile acute illness lasting 4 to 8 weeks, most remain asymptomatic until cardiac or gastrointestinal manifestations occur 1 to 3 decades after infection. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250963

Toxocariasis and eosinophilia: Parasitic infections — such as with Toxocara — are a common cause of eosinophilia in tropical regions but are less common in Canada. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250714

Surgical versus percutaneous revascularization: The risk of adverse events was significantly elevated for 1 year among patients who underwent coronary artery bypass grafting versus percutaneous coronary intervention. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250312

Chagas disease: who is at risk? CMAJ Volume 197, Issue 42, features new articles on chagas disease; surgical versus percutaneous revascularization, and more. ➡️ www.cmaj.ca/content/197/42

This week on #CMAJPodcasts, we discuss the diagnosis and management of celiac disease with Jedid-Jah Blom and Dr. Maria Ines Pinto-Sánchez. ➡️ www.cmaj.ca/transcript-2...

Definition of merit in admissions: "The definition and assessment of merit for medical school admissions must consider population health needs and the recruitment of a diverse health workforce as an evidence-based contribution to the path forward." ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251020

Cutaneous systemic lupus erythematosus: Between 30% and 50% of patients with systemic lupus erythematosus will have cutaneous involvement over their lifespan. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250991

Chronic spontaneous urticaria: Chronic spontaneous urticaria presents as hives with or without angioedema for more than 6 weeks. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250818

Congenital haptoglobin deficiency: Dark or tea-coloured urine has many different causes, including dehydration, medications, urinary tract infections, and hemolytic disorders. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250985

HIV prophylaxis guideline update: Multiple safe, effective PrEP and PEP regimens are now available in Canada, making it increasingly possible to find suitable options for all who could benefit. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250511

Adolescents and young adults with cancer: Both palliative care and intensive care are increasingly used among adolescents and young adults with cancer at the end of life in Ontario, Canada. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250615

Proud to announce on World AIDS Day today that our 2025 update to Canadian guideline on HIV PrEP and PEP is now published in @cmaj.ca! The guideline include 31 recommendations and 10 good practice statements to support clinical decision making. Learn more 👉 doi.org/10.1503/cmaj...

Now published in @cmaj.ca: a 2025 update to Canadian guidelines on HIV PrEP and PEP.  Led by CTN+’s Dr. Darrell Tan, these guidelines include 31 recommendations and 10 good practice statements to support clinical decision making, developed by experts from across Canada.    👉  https://bit.ly/3MyNfNG

"Overcoming disruption, transforming the AIDS response" That's the theme of Worlds AIDS Day 2025, and it is light of that theme that we are so pleased to announce the updated Canadian PrEP and PeP Guidelines, published in @cmaj.ca! (1/2)

HIV Prophylaxis: what is the latest guidance? CMAJ Volume 197, Issue 41, features new articles on HIV prophylaxis guideline update; adolescents and young adults with cancer, and more. ➡️ www.cmaj.ca/content/197/41

Permission to exist: "My most profound validation came not from colleagues or committees, but from my patients" ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250941

Involuntary treatment for substance use: Instead of instituting ethically fraught interventions with weak evidentiary support, provinces should strengthen and evaluate a full spectrum of patient-centred, evidence-based services, for patients. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250910

Thymic hyperplasia: Thymic hyperplasia, common in children and adolescents, is unusual in adults owing to age-related involution. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250929

Extreme heat exposure: Extreme heat poses substantial health risks, with older adults, people with chronic illnesses, and those unable to limit exposure most at risk. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250951

Myocardial infarction with nonobstructive coronary arteries: Until recently, MINOCA was thought to be uncommon; however, recent analyses have estimated that 6-15% of acute coronary syndrome occurs in the absence of obstructive coronary artery disease. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250774

A pediatric asthma clinical pathway embedded in an electronic medical record for use by primary care practices did not improve the proportion of children in primary care who were prescribed or dispensed a controller medication for asthma. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.241694

Myocardial infarction with nonobstructive coronary artery disease: what is the management? CMAJ Volume 197, Issue 40, features new articles on myocardial infarction with nonobstructive coronary arteries; involuntary treatment for substance use, and more. ➡️ www.cmaj.ca/content/197/40

Staff physician burnout: Burnout among staff physicians threatens teaching quality, patient safety, and the sustainability of both the clinical learning environment and the broader health care system. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250852

Occult toddler's fracture: A toddler’s fracture is a nondisplaced tibial fracture in a young child between the ages of 1 and 4 years, typically resulting from a low-energy injury. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250808

Cardiac thrombus: The differential diagnosis of a left atrial mass is broad, including thrombus, infection, myxoma, lipoma, sarcoma, and metastatic tumour. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250697

Fertility preservation and cancer treatment: Ovarian tissue cryopreservation is the only fertility preservation option for patients with ovaries who cannot undergo ovarian stimulation. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250519

Patient expectations and pay inequality: Physician and patient identities influence the ways that expectations are formed, communicated, and perceived, helping explain observed differences in income based on physician gender, race, and immigration status. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250665

Fertility preservation prior to cancer treatment: what are the options? CMAJ Volume 197, Issue 39, features new articles on fertility preservation by cryobanking; staff physician burnout; family physician pay inequality, and more. ➡️ www.cmaj.ca/content/197/39

This week on #CMAJPodcasts, we discuss access to mental health care for Black youth with Mercedes Sobers and Dr. Amy Gajaria. They unpack study findings and describe a program offering culturally adapted care and trust-building. ➡️ www.cmaj.ca/transcript-241733

Government partnerships and virtual care: Independent evaluation of corporate virtual care partnerships can confirm that equity, safety, privacy, and transparency criteria are met and maintained. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250639

Halo nevi: Adult-onset halo nevi are associated with a 1% risk of developing primary cutaneous melanoma 1 year after halo nevus diagnosis. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250684

Eustachian tube dysfunction: Allergic rhinitis, chronic rhinosinusitis, gastroesophageal reflux disease, and smoking increase risk and severity of eustachian tube dysfunction. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250163

Pediatric abdominal trauma poses a diagnostic challenge, balancing the need to rule out clinically important intra-abdominal injury against the risks of radiation exposure, given children’s increased sensitivity to radiation-induced malignancies. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250736

Distance to primary care: More than 1 in 10 patients in urban or suburban regions who were rostered to a family physician in a patient enrolment model in Ontario lived farther than 30 km from their family doctor. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250265

Corporate virtual primary care: what are the impacts on access and equity? CMAJ Volume 197, Issue 37, features new articles on government partnerships and virtual care; distance to primary care; pediatric blunt abdominal trauma, and more. ➡️ www.cmaj.ca/content/197/37

"The escalation of opioid use among youth is being overlooked. Existing addiction services are also inadequate to meet the needs of young people with opioid use disorder (OUD)." — The Globe and Mail ➡️ www.theglobeandmail.com/canada/artic... Learn more in the CMAJ ➡️ doi.org/10.1503/cmaj...

Yes, and….: "'Yes, and …' is a philosophy of resilience, a way of not dwelling, of keeping the pedals turning when the road disappears." ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251072

Rational opioid prescribing: Rational opioid prescribing not only respects the pharmacology of opioids, but also funnels fewer patients into chronic use and addiction. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251666

Youth and the opioid crisis: "There is no excuse for health systems’ inaction and lack of investment to provide evidence-based addictions services for youth." ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251682