Lecanemab for early Alzheimer disease: Lecanemab is a humanized monoclonal antibody that binds soluble brain amyloid-β protein, promoting its removal and slowing the underlying process of Alzheimer disease. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260193

Adverse effects from sedatives in older adults: This research study's findings have important implications for in-hospital medication review and falls-risk assessment for older adults in Canada. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251965

Rheumatoid synovitis: Important differentials for nodular elbow swelling in rheumatoid arthritis include rheumatoid nodules, gouty tophi, olecranon bursitis, and methotrexate-induced accelerated nodulosis. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252052

Fatal rabies in a child: Rabies postexposure prophylaxis is highly effective in preventing infection in exposed humans if given promptly and before onset of rabies symptoms. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251933

🎉 CMAJ Podcasts just hit ONE MILLION downloads! Thank you to everyone who has listened, shared, and supported the show. People truly value trusted health information — accurate, evidence‑based conversations matter more than ever. Listen + subscribe: CMAJ.ca ➡️ www.cmaj.ca/page/multime...

Swimming pool closures: Community pools are disappearing from the Canadian landscape, often among the first casualties of tightening public budgets. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260959

Otitis externa: Infection of the external auditory canal occurs most often after moisture exposure or minor trauma to the ear canal. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260196

🩺🔍 Otitis externa: what’s the latest on diagnosis and management? Read new articles on otitis externa; fatal rabies in a child; adverse effects from sedatives in older adults; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/25

Purple urine bag syndrome: Purple urine bag syndrome is a benign condition resulting from microbial metabolism of tryptophan into indigo and indirubin pigments that adhere to the catheter and bag surfaces, producing a purple coloration. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260150

Neuroinvasive eastern equine encephalitis: Neuroinvasive eastern equine encephalitis is a rare and severe mosquito-borne disease that occurs in North America. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252021

Ebola virus disease: Ebolaviruses transmit person-to-person through bodily fluid contact (e.g., blood, vomit, diarrhea, semen) or contaminated fomites. Here are 5 things to know ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260834

🩺🔍 Ebola virus disease: what’s the latest on diagnosis and management? Read new articles on Ebola virus disease; hantavirus; purple urine bag syndrome; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/24

We're proud to announce that CMAJ's 2025 Journal Impact Factor is 12.7! Thank you to all who have contributed to the research and scholarship that inform health care in Canada and around the world.

Gout associated with bempedoic acid: Clinical trials have reported gout in about 3% of patients treated with bempedoic acid, a cholesterol lowering medication. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252158

Here’s the original article published by @cmaj.ca Have a great and safe Pride! 🏳️‍🌈🏳️‍⚧️ www.cmaj.ca/content/197/...

The rise of #ClimateChange also means the emergence of climate-sensitive infectious diseases, which pose significant risks to human health. Through collaboration, information sharing, and advocacy, here's how physicians can prepare for what comes next. Read more @cmaj.ca: bit.ly/4v469Oa

Paraneoplastic neurologic syndrome: Paraneoplastic neurologic syndromes can present with a wide range of neurologic symptoms, sometimes with an acute onset. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251204

The bench: A physician reflects on the purpose of a public bench outside his office window Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260102

📢 Nous cherchons des médecins pour animer un nouveau balado médical! Si vous aimez poser des questions et approfondir des enjeux médicaux variés, nous voulons vous entendre. Tous les détails et la façon de postuler ➡️ https://www.cmaj.ca/jamc-balado Date limite : 26 juin 2026

Trauma centres and traumatic brain injury: This study's results suggest inequities and underscore the need for system level strategies to ensure equitable triage and transfer practices. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251721

Hypersensitivity reactions to contrast: Iodinated contrast media (ICM) used in current practice carry a low risk of hypersensitivity reactions. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260319

🩺🔍 Tophaceous gout associated with bempedoic acid: what is the management? Read new articles on gout associated with bempedoic acid; trauma centres and traumatic brain injury; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/23

Anesthesiology human resources: Anesthesia for cataract surgery in Canada: deploying a limited workforce where it matters most. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260327

Living with visual impairment: Patients with visual impairment experience barriers to accessing health care. Here are 5 ways to support ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251872

Splenic infarction and sickle cell trait: Patients with sickle cell trait inherit only 1 sickle cell gene, usually remain asymptomatic, and can be unaware of their status. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252096

Recurrent pustular psoriasis of pregnancy: Pustular psoriasis of pregnancy is a rare dermatosis of pregnancy that can lead to life-threatening maternal and fetal complications. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251460

Cataract surgery and anesthesiology: Research findings suggest the use of physician anesthesiology care for routine cataract surgery should be reconsidered. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250814

🩺🔍 Living with visual impairment: how can physicians support patients? Read new articles on living with visual impairment; splenic infarction and sickle cell trait; recurrent pustular psoriasis of pregnancy; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/22

Acetaminophen in pregnancy: More than half of pregnant people use acetaminophen, most commonly for pain. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260138

Keratoacanthoma is classified as a subtype of well-differentiated cutaneous squamous cell carcinoma. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252150

A university hospital photovoice study examining the experiences of Eeyou/Eenou patients receiving care and people supporting a patient ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250777

Afebrile osteomyelitis presenting in an infants: Prompt diagnosis of acute osteomyelitis is crucial to prevent progression to chronic osteomyelitis and an increased risk of complications, such as Brodie abscesses. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251060

This week on #CMAJPodcasts, Drs. Andrés Delgado-Ron and Marieta Pehlivanova talk to us about near-death experiences, from how they differ from delirium or hallucinations to why dismissive reactions to these experiences can be harmful. ➡️ https://www.cmaj.ca/transcript-252003

This week’s Editor’s Pick cuts through online noise to explain what the evidence actually shows about acetaminophen use during pregnancy, supporting informed discussions between clinicians and patients. Read the article in CMAJ ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260138

All My Relations Advisory Board: Research involving Indigenous participants requires a commitment to respect for Indigenous values and incorporating Indigenous Ways of Knowing, as well as involving Indigenous partners early in the planning of the project. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250735

🩺🔍 Acetaminophen use in pregnancy: what is the latest evidence? Read new articles on acetaminophen in pregnancy; pseudoparalysis in an infant; keratoacanthoma; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/21

Urinary incontinence: management and quality of life from a patient’s perspective, in their own words. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260760

Female urinary incontinence: Who is at risk and what causes it? How is it diagnosed? How is it treated? Which patients should be referred to a specialist? What are novel emerging treatments for it? Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.241715

🩺🔍 Female urinary incontinence: what is the latest management? Read new articles on female urinary incontinence; near-death experiences; risk of acute kidney injury and preeclampsia; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/20

Locally acquired ascariasis infections in Canada are rare, and the diagnosis is made by identifying the expelled adult worm. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251445

Platypnea–orthodeoxia syndrome: An 86-year-old woman presented to our emergency department with a 1-week history of worsening of chronic dyspnea and new confusion. Learn more about platypnea–orthodeoxia syndrome in this clinical case ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251337

Climate change and emerging diseases: Emerging diseases related to climate change pose health risks and diagnostic challenges in new Canadian locations. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.260668

A 51-year-old man presented to hospital with a 2-week history of fever, chills, headache, dyspnea, dry cough, gastrointestinal symptoms, transient pruritic arm rash, and blurred vision after he was bitten by insects while gardening. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252050

Rocky Mountain spotted fever is a severe tick-borne infection. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251935

This week on #CMAJPodcasts, we're joined by Dr. Sony Singh and Bailey Milne to explore how deep infiltrating endometriosis can invade adjacent organs and the risk of congenital anomalies for infants born to patients with endometriosis. ➡️ https://www.cmaj.ca/transcript-260662

Prenatal syphilis screening: Timely prenatal syphilis screening is critical for preventing congenital syphilis infection. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251757

🩺🔍 Worm in stool: what is the work-up and management? CMAJ Volume 198, Issue 19 includes new articles on locally acquired ascariasis; Rocky Mountain spotted fever; climate change and emerging diseases; and more. ➡️ https://www.cmaj.ca/content/198/19

Oral manifestations of syphilis: Oral manifestations can be the first and sometimes only sign of syphilis and can occur at any stage of this disease. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251915

Caregivers for people in their last year of life: Clinicians should recognize and respond to escalating caregiver burden in the care recipient’s last year of life. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.252034

Arginine vasopressin disorders: Diabetes insipidus has been renamed to arginine vasopressin disorders for clarity and safety. ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251716