Next week Wednesday-Friday I will be in Wroclaw mainly to attend an oncology conference at Łukasiewicz - PORT. I will be there with our distributor Labsoft to talk about Bruker Fluorescence Microscopy microscopes to whoever is willing to listen :-)

Last week we installed the Bruker Fluorescence Microscopy Ultima 2P Plus multiphoton in Krakow, Poland at the Uniwersytet Jagielloński-Collegium Medicum. How the week ended vs. how it started 👇

21st century dev bio at its best! I can't help but point out that not one but two Bruker microscopes (Acquifer IM, MuVi) were used for gentle&long term time lapse imaging of developing Nematostella here. No need to mount your invertebrate (cnidaria, planaria, crustaceans), we can do the time lapse!

Now published. Congrats to Soham and all co-authors! www.science.org/doi/10.1126/.... @embl.org

Like last year, we are running an online Bruker Fluorescence Microscopy neuroscience miniconference. It is focused on the actual science one can do with our microscopes presented by researchers, not sales presentations.

We are looking for an experienced light microscopy specialist, motivated to support our users in the Advanced Light Microscopy Facility at EMBL Heidelberg. embl.wd103.myworkdayjobs.com/en-US/EMBL/j... -closing date 11 May 2026 @eurobioimaging.bsky.social @globalbioimaging.bsky.social

I suppose most EU zebrafish researchers will attend European zebrafish meeting in July in Vienna #EZM2026. It is going to be a great event like the previous one in Krakow. Important note for you: Come early, already on 6th in the evening. The conference starts with Bruker Luxendo workshop on 7th.

Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work! www.cell.com/cell/fulltex... @embl.org

Whoever tried some lightsheet microscopy knows that image acquisition is the fun easy part. The real challenge comes later. This @brukercorporation.bsky.social Luxendo podcast episode touches on the real challenges. www.youtube.com/watch?v=tAjl...

📢New behind the paper story Using the #zebrafish retina as a model, Jaakko Lehtimäki @jalehtimaki.bsky.social, Caren Norden @nordenlab.bsky.social & team dissect multipolar migration in the developing brain. In this post, Jaakko takes us through their research.

Lovely perspective on the recent paper by @nordenlab.bsky.social, written by first-author (and former Postdoc) @jalehtimaki.bsky.social 🐟 🔗 to feature: focalplane.biologists.com/2026/03/11/s... 🔗 to original research paper ICYMI: www.sciencedirect.com/science/arti...

New work from Metz Lab @ribesresearch.bsky.social 🐟 🔗 to paper: journals.biologists.com/jeb/article/...

If you are going to the 1st German Fish Model Research Meeting" in Heidleberg in September, consider signing up for Bruker workshop. The registration is already open. We will cover high throughput screening as well as time-lapse imaging on a lightsheet. www.bruker.com/en/news-and-...

One of the Bruker FM products I sell to light microscopists is a server for image processing and storage, the HIVE. >150 mainly imaging facilities over the years thought it is a good idea to get a HIVE and I'm sure they still do. Even the first installs now 10 years old are mostly still running.

I talked about this server for image processing and storage to all microscopists that were willing to listen (also to those not refusing too actively). HIVE underwent an upgrade for next generation hardware. So it is time for everyone's favorite pastime activity...a webinar! goto.bruker.com/4aCYm0J

For whoever going to BonnBrain in March, consider extending your stay by one day and participate in our hands-on! workshop. Imaging neuronal activity with Inscopix 2P miniscope and voltage imaging with the Ultima 2P Plus multiphoton microscope. www.bruker.com/en/news-and-...

Eye candy: article about expansion microscopy of protists. www.quantamagazine.org/expansion-mi... Unicellular eukaryotic diversity is often overlooked but I'm thankful it was part of curriculum during my undergrad in Prague. There is exciting and weird cell biology going on in different protists.

1/10 New preprint on bioRxiv Nanodiamonds for spatial resolution benchmarking in two-photon microscopy We introduce nanodiamond-based phantoms as a robust, reusable alternative to bead–agarose samples for PSF calibration. www.biorxiv.org/content/10.6...

Deadline for abstract submission in one week! I'm sharing this reminder because right after the conference we have an open demo day at DZNE Bonn, which will include voltage imaging on Bruker 2P microscope and Ca imaging in freely moving mice with Inscopix miniscopes www.bruker.com/en/news-and-...

We are hosting a demo day for @brukercorporation.bsky.social two photon microscopes and Inscopix miniscopes. 📅 March 26th 2026 📌 DZNE in Bonn Whole day event with hands on sessions, presentations and discussions with our existing 2P users. Register: www.bruker.com/en/news-and-...

We are hosting a demo day for @brukercorporation.bsky.social two photon microscopes and Inscopix miniscopes. 📅 March 26th 2026 📌 DZNE in Bonn Whole day event with hands on sessions, presentations and discussions with our existing 2P users. Register: www.bruker.com/en/news-and-...

We (Bruker Fluorescence Microscopy) will run a satellite event on March 26th. A mixture of a hands on demo of our 2P and miniscopes and our user meeting. One can attend independently of the conference, so this is a free event for anyone who can make a daytrip to Bonn. www.bruker.com/en/news-and-...

First @brukercorporation.bsky.social (and mine) lightsheet microscope sale in Poland and it is straight away our most complex lattice system even with an IR laser photomanipulation module. Joint project with our distributor in Poland Labsoft.

Application is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!

Join us for BonnBrain 2026! The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline. Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!

Still looking for ptf1a promoter 🔍

First @brukercorporation.bsky.social (and mine) lightsheet microscope sale in Poland and it is straight away our most complex lattice system even with an IR laser photomanipulation module. Joint project with our distributor in Poland Labsoft.

I meant to post it long time ago but things have been busy. Still, this article is worth sharing even if not breaking news. Researchers at Tsinghua University developed a new approach to tissue clearing, VIVIT, using among other instruments, the Bruker MuVi SPIM www.sciencedirect.com/science/arti...

Development of the zebrafish retina captured on a light sheet microscope. Credit to @ichajaroslav.bsky.social. #ZebrafishZunday 🧪

Are you interested in long time lapse imaging of organoids? In this example, retinal organoids were imaged in high throughput for 3 days. The aim was to collect sufficient data to be able to use machine learning for predicting organoid differentiation just from brightfield images.

🔥 It's Time ! #Mifobio2025 👉 imabio-cnrs.fr #GDRImabio @cnrs.fr @cnrsingenierie.bsky.social @cnrsbiologie.bsky.social

For those at Seeing is Believing in Heidelberg right now, do join our workshop, which is about to start soon at 11:30! www.embl.org/about/info/c... Focus on organoid time lapse imaging, with high throughput options as well. #EESImaging

🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/

✨🔬 #FluorescenceFriday Confocal stack of chicken retina 🐥 — from inner nerve fibers up to photoreceptors. Layer upon layer of mosaics, each cell type in its place. Birds have remarkable visual systems, and under the microscope, they look absolutely stunning in detail.

The #SCZI2026 Oral Abstract and Workshop proposal deadline has been extended! They are now due September 24th at 11:59pm EDT. Register and Submit here: www.izfs.org/education/11...

We have just installed a third HIVE server in Czechia. After Prague and Brno, we are adding Olomouc! www.bruker.com/de/products-... Researchers often get HIVE to handle data from Luxendo as well as other companies' light-sheet scopes but it is a rather universal solution for big data management.

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

🚨 Final bits are falling into place for #UKZF2025 🎉 The organisers are buzzing with excitement and can’t wait to welcome the zebrafish community to Exeter & Exmouth TODAY 🐟✨

Wow, that was amazing! We thank everyone for attending the V4SDB 2025 meeting! You all made it an excellent conference, where we had the opportunity to hear from outstanding speakers,share ideas and experiences, and of course have some unforgettable time during social activities!

Happy to be at the #V4SDB 2025 developmental biology conference. Amazing quality of the talks and a beautiful venue in the High Tatras in Slovakia. @v4sdb.bsky.social v4sdb2025.img.cas.cz/programme/

Good morning everyone! Welcome to Day 2 of the V4SDB Meeting 2025! Yesterday was full of events, but grab some coffee - there's still so much more to discover! #V4SDB2025 #conference #developmentalbiology #evodevo #morphogenesis #organoids

Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social ‬ & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...

#LISH25 was BIG.

The Company of Biologists Workshops 2027: Excited to share that our workshop concept, "Bridging Scales and Disciplines to Understand Robust Development”, has been selected! 🤩@giuliapaci.bsky.social and I are looking forward to organizing it. Stay tuned for details! @biologists.bsky.social

#LISH25 final student team presentations. #The_Holy_de_Broglies

#LISH25 day 10 ushered in by Claudia Gerri from @mpi-cbg.de introducing us to the wonderful world of mammalian early embryo development, implantation and #placenta interactions. Showing light sheet data from ex #LoPaT - Michi Burkon 💕. Walk-up song with Italian flair came with sweets.

Really nice thread about the infrared co-illumination to reduce photobleaching of GFP. I was aware of the Ludvíkova et al paper but didn’t realize that lightsheet is the main modality, which would benefit from it.

How many photons are in a GFP? — more than last year, and more than you thought. Here's a simple, cheap, and practical method to break a fundamental limit in fluorescence microscopy. But it only works in light sheet!