Hsieh-Wilson Lab @ Caltech (@hsiehwilsonlab.bsky.social)

We integrated experimental and computational approaches to generate a systems-level view of a key post-translational modification, O-GlcNAc. In vivo studies across tissues reveal shared and tissue-specific functions. Congrats to Matt, John, Yao, and the whole team! #NOTISEme bit.ly/3ZgCOBM

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Functional analysis of O-GlcNAcylation by networking of OGT interactors and substrates - Nature Chemical Biology Functional studies of O-GlcNAcylation have often focused on individual modifications. Now, a systems-level approach has identified simultaneous O-GlcNAcylation events that coordinate cellular activiti... https://doi.org/10.1038/s41589-025-02108-7