The next Protein Structure Evolution (ProSE) seminar is this afternoon, 4pm UK time. Stephen Fried on why some microbes refold their proteins and others don't! Registration link: tinyurl.com/prose-seminar2

Looking forward to re-starting the Protein Structure Evolution (ProSE) seminar series next week! We have a great line up of talks on cutting-edge work over the next few weeks. Register here: tinyurl.com/prose-seminar2

I'm glad to now be an academic editor for PLOS Computational Biology @plos.org, expecting to handle 1-2 manuscripts a month. If you're a postdoc in microbial evolutionary genomics / other 'omics topics interested in review experience, let me know - I will be looking for reviewers!

Conference on large-scale analyses of eukaryotic reference genomes - with bursaries available! coursesandconferences.wellcomeconnectingscience.org/event/unders...

Next ProSE seminar is today! "Computational Insights into Protein Adaptation Across Environmental Gradients"

The exciting next seminar in our Protein Structure Evolution (ProSE) online seminar series - tomorrow! Sign up at the link here.

Very interesting new study from authors including Nobel Prize winner David Baker. I'm glad that it cites one of my related papers 😀 I've faced plenty of skepticism from editors & others about the importance of this line of research, perhaps this will shift ... www.biorxiv.org/content/10.1...

To live in Cambridge is to be surrounded by amazing built history. One favourite of mine is the Round Church, where I've had the privilege of speaking a couple of times. It was built approx. ~1130AD, likely before the first human settlement in my homeland of NZ 🤯 en.wikipedia.org/wiki/Church_...

Next up in the ProSE seminar series, tomorrow: Come hear about my current project on protein structure evolution over the very long term!

We have an exciting programme of talks for the ProSE seminars (Protein Structure Evolution). The first session was an inspiring and provocative talk by leader in the field Prof. Andrei Lupas. Next up, 11th March, I'll be speaking about my work on evolution over extremely long time periods.

🧬 New research reveals that encoded & non-genetic protein variants shape the human proteome in ways previously unknown! These **alternative proteoforms** expand protein function bypassing genetic constraints. 🔗 Check it!: www.biorxiv.org/content/10.1... #Proteomics #CentralDogma #Translation

Delighted to share our preprint on the evolution of pandemic cholera at its global source in the ganges basin! doi.org/10.1101/2025.02.03.25321585

Join our new seminar series on protein structure evolution! This is an exciting and rapidly growing new field drawing on multiple subfields of biology. 💡🦠🧬🌱🐘 Monthly discussions, open to any interested students or researchers.

I'm excited to be co-hosting a seminar series on Protein Structure Evolution, presenting some of the exciting work in this field. Talk 1: Speaker: Andrei Lupas Topic: "Highly repetitive genomic ORFs: a source of new fibrous proteins?" 📅 Feb. 11, 3PM GMT 🔗 tinyurl.com/prose-seminar1 Please share!

Michael Lynch, Evolutionary Cell Biology (2024): “Many biologists are content to live in a pure Dawkinsian world in which every aspect of biological diversification was set down for adaptive reasons, but details at the molecular and cellular level suggest that this vision is far from the truth.”

A recent talk I gave at the Faraday Institute for Science & Religion, Cambridge, relating recent developments to some old very big questions; and based partly on some forthcoming scientific work, is now online: www.youtube.com/watch?v=FYxl... www.faraday.cam.ac.uk/event/dr-zac...

A starter pack of scientists working in molecular evolution and population genetics, with an emphasis on the human and virological. go.bsky.app/2xnyMrS

Hello 🦋! I'm a research fellow investigating the evolution of protein novelty (sequence, structure, function) and 'overlapping genes' in bacteria and viruses. Based in beautiful Cambridge, UK, working @Wellcome Sanger Institute. Further info on my research & other interests: www.zacharyardern.com