The results of a recent study suggest that dietary changes, specifically the ratio of poly- to monounsaturated fatty acids, may affect the effectiveness of vaccines and cancer therapies. lifespan.io/news/fat-com... By: @arkadimazin.bsky.social

A recent study describes how the susceptibility of older organisms to pneumonia is related to inflammatory factors.🔥 A chronic inflammatory environment in older organisms contributes to some immune cells’ inability to fight infection. lifespan.io/news/how-inf... By: Josh Conway

🧠🏋️‍♀️ A new study suggests that both heavy and moderate resistance training slows brain aging in older adults. lifespan.io/news/resista... By: @drangowskaway.bsky.social

Scientists have discovered that ATP deficiency disrupts dopamine processing, leading to the accumulation of the harmful proteins that characterize Parkinson’s disease. 💊ATP supplementation helps, but the road to the clinic might be long. lifespan.io/news/novel-m... By: @arkadimazin.bsky.social

The February Rejuvenation Roundup is here! Plenty of crucial work has been done in the #rejuvenation world over the past four weeks, and last month, we’ve spoken to several researchers about the progress being made. lifespan.io/news/rejuven...

The field of cellular reprogramming is maturing quickly, with its first clinical trials just around the corner. We asked experts to discuss the opportunities and bottlenecks the field faces, and to offer predictions for the future. lifespan.io/news/cellula... By: @arkadimazin.bsky.social

A new study described how age-related changes in key metabolic pathways cause human adipose-derived stem cells to lose functional capabilities. lifespan.io/news/a-metab... By: Josh Conway

At a time when the debate around longevity is moving into the mainstream, it's essential to address the ethics of longevity science. Lifespan News discussed this topic with João Pedro de Magalhães in a recent interview. lifespan.io/news/joao-pe... By: @arkadimazin.bsky.social

👵An analysis of over 800,000 women found no association between menopausal hormone therapy and increased mortality. For some groups of women, this therapy lowers mortality risk. lifespan.io/news/menopau... By: @drangowskaway.bsky.social

Scientists have discovered that, like brown fat, white fat has a mechanism that burns fuel to produce heat. 🔥 This effect could potentially be used to create weight loss drugs. lifespan.io/news/thermog... By: @arkadimazin.bsky.social

A new study investigated how the sirtuin SIRT6 protects against proteostasis-related brain 🧠 disorders by limiting protein production. lifespan.io/news/how-a-s... By: Josh Conway

DeepRare, a new AI tool, outperformed several other models and human physicians in diagnosing rare diseases. lifespan.io/news/ai-tool... By: @arkadimazin.bsky.social

A recent study suggests that: 🔴 The inflammatory factor IL6 causes increased mortality, while 🟢 Its circulating receptor, IL6R, causes increased longevity and protects against a variety of conditions. lifespan.io/news/a-circu... By: Josh Conway

A recent study suggests that cognitive enrichment 📚🌍📰throughout life: 🧠is associated with reduced dementia risk, and 🧠has the potential to delay the onset of dementia and mild cognitive impairment by five to seven years. lifespan.io/news/lifetim... By: @drangowskaway.bsky.social

🥦🥕🥑🥩Scientists have compared five diets to determine which is associated with more years of life gained. The most lifespan-correlated diet differed between men and women. ♀️♂️ lifespan.io/news/new-stu... By: @arkadimazin.bsky.social

🧠Altering a growth hormone receptor in the adipose tissue of aged male mice slows cognitive aging and enables them to perform substantially better on cognitive tests, a study suggests. lifespan.io/news/silenci... By: Josh Conway

🧠Rejuvenating memory-encoding neurons improved memory in Alzheimer’s disease models and in wild-type mice. lifespan.io/news/cellula... #aging #dementia #AD #neurobio By: @arkadimazin.bsky.social

A team of researchers has biologically engineered immune cells to directly attack the characteristic amyloid plaques of Alzheimer’s disease.🧠 lifespan.io/news/creatin... By: Josh Conway

In a recent study, researchers transferred microbiota from young to aged mice. 🦠🐁 The transfer helped to restore molecular signaling necessary for proper intestinal function and improved the regenerative capacity of intestinal stem cells. lifespan.io/news/young-m... By: @drangowskaway.bsky.social

A new study links sleep loss 😴 to: 🧠problems with white matter, 🧠myelin thinning (a protective sheath around the projections of nerve cells called axons), 🧠decrease in cognitive abilities. However, some of the damage can be reversed. lifespan.io/news/sleep-d... By: @arkadimazin.bsky.social

A new study described: 🔴 Why do older natural killer cells lose their ability to eliminate harmful cells, and 🟢 A potential treatment for this decline that allows those cells to perform more like younger cells lifespan.io/news/restori... #aging #rejuvenation #lifespan By: Josh Conway

Life Biosciences has announced that its trial of cellular reprogramming aimed at two age-related vision diseases has received a go-ahead from the FDA. Lifespan News spoke with the company’s CSO to get more details. lifespan.io/news/first-h... By: @arkadimazin.bsky.social

A subset of senescent cells treated with senolytics survives, but a recent study suggests that mitochondrial stress can enhance the effectiveness of senolytics. lifespan.io/news/increas... By: Josh Conway

A recent study suggested that higher vitamin intake, particularly of Vitamins C and B2, is associated with slower biological aging. However, not all vitamins showed the same beneficial effects. lifespan.io/news/associa... By: @drangowskaway.bsky.social

When it comes to building muscle, 💪 are fewer repetitions at higher loads better than more repetitions at lower loads? 🏋️ The news study suggests no significant differences between those approaches. lifespan.io/news/weight-... By: @arkadimazin.bsky.social

The January Rejuvenation Roundup is here! 2026 has kicked off with several key research insights, and we’ve taken a look at the state of the industry and how rejuvenation biotechnology is moving forward. Read more 👇 lifespan.io/news/rejuven...

🧬🧠Using an ingenious CRISPR-based screening technique, scientists have found a protein that tags tau, Alzheimer's-associated protein, for degradation and is more strongly expressed in tau-resilient neurons. lifespan.io/news/crispr-... By: @arkadimazin.bsky.social

A new study reported that engineered small extracellular vesicles (sEVs) fused with plasma membrane proteins successfully treated heart arrhythmia in a rat model. lifespan.io/news/enginee... By: Josh Conway

A new study found that shingles vaccination 💉 is associated with: 🔥lower inflammation scores, 🧬slower epigenetic and transcriptomic aging, and 🧓a lower composite biological aging score. lifespan.io/news/shingle... By: @drangowskaway.bsky.social

A new study uncovered a potential new mechanism by which rapamycin counters immunosenescence. 💊 Rapamycin appears to directly reduce DNA damage burden in immune cells. 🧬 lifespan.io/news/rapamyc... By: @arkadimazin.bsky.social

Researchers established that cells derived from the human placenta may be useful in rapidly testing potential anti-aging treatments. lifespan.io/news/using-p... By: Josh Conway

🏃‍♂️🏋️‍♀️🏊‍♂️🚴‍♂️Regularly engaging in a variety of types of physical activity is associated with significantly lower all-cause mortality, a study suggests. The amount of exercise matters as well, but the effect plateaus quickly. lifespan.io/news/exercis... By: @arkadimazin.bsky.social

Researchers investigated TSP-1, a compound critical for cognitive maintenance, whose levels decrease with age. They learned that TSP-1 is secreted by normal brain cells called astrocytes (promoting neuronal connections), but not by senescent astrocytes. lifespan.io/news/how-sen... By: Josh Conway

👶Does having babies impact how fast you age? A new study that investigated various childbearing trajectories suggests accelerated aging and increased mortality risk in women with multiple live births, as well as childless women. lifespan.io/news/the-imp... By: @drangowskaway.bsky.social

How does obesity drive chronic inflammation?🔥 A recent study discovered that obesity causes macrophages (immune cells) to ramp up mitochondrial DNA production, leading to more inflammation.🔥 lifespan.io/news/study-u... By: @arkadimazin.bsky.social

A recent review described the aging of the hematopoietic system, which is responsible for the creation of blood. It suggests that aging-related inflammation drives the proliferation of unhelpful cells. lifespan.io/news/a-new-l... By: Josh Conway

🧠 According to a new study, as many as 90% of Alzheimer’s cases can be attributed to “suboptimal” variants of the APOE gene. lifespan.io/news/vast-ma... By: @arkadimazin.bsky.social

In the last installment of our end-of-year series of expert roundups, we asked six prominent figures in longevity advocacy to share their thoughts on the movement’s ups and downs in 2025 and its prospects going into 2026. lifespan.io/news/longevi... @statto.bsky.social By: @arkadimazin.bsky.social

A recent review of literature investigated the risks and benefits of hormone replacement therapy. The authors point out that this approach could be used as a geroprotector to extend the healthspan of women. lifespan.io/news/the-ger... By: @drangowskaway.bsky.social #WomensHealth #aging #menopause

2025 was a good year for geroscience. Yet, the path wasn’t always smooth. W asked five prominent geroscientists to share their perspectives on the highs and lows of 2025, along with their outlook for 2026. lifespan.io/news/gerosci... By: @arkadimazin.bsky.social

Researchers have found that Hevin, a protein that increases with age, leads to heart problems in older male mice. lifespan.io/news/a-prote... By: Josh Conway #aging #CardiovascularHealth

By inhibiting the aging-related enzyme 15-PGDH, scientists have shifted cartilage cells towards a healthier phenotype, leading to a significant improvement in a mouse model of osteoarthritis. lifespan.io/news/a-small... By: @arkadimazin.bsky.social

In a recent study, researchers have described how older cells send a specific kind of aging-associated RNA to other cells in extracellular vesicles (EVs), spurring inflammation.🔥 lifespan.io/news/how-har... By: Josh Conway

🧠An investigation into Alzheimer’s disease-related biomarkers provided insights into the molecular processes that contribute to improved cognition following treatment with a human recombinant protein. lifespan.io/news/recombi... By: @drangowskaway.bsky.social

How did the year 2025 turn out for longevity biotech? Was it surprising or more of the same? Exciting or disappointing? What should we expect in 2026? We asked five leading experts to weigh in. lifespan.io/news/longevi... By: @arkadimazin.bsky.social

Scientists have found that a single microbial 🦠 species can blunt the negative effects of a high-fat diet 🍔 by producing a unique mix of lipids. lifespan.io/news/a-singl... By: @arkadimazin.bsky.social

The December Rejuvenation Roundup is here! Catch up with the aging and rejuvenation news from the last month of 2025: ✨Editorial Summarizing 2025 ✨Interview with Maximina Yun on the Wonders of the Axolotl ✨Quality of Preclinical Anti-Aging Research & more! lifespan.io/news/rejuven...

A recent review evaluated studies that included over 5.5 million participants to assess the impact of multivitamin and mineral supplements on different aspects of health. www.lifespan.io/news/how-mul... By: @drangowskaway.bsky.social

Researchers have identified a key protein in age-related hearing loss. Suppressing this protein led to significantly improved hearing in a mouse model. www.lifespan.io/news/researc... By: Josh Conway

Scientists have discovered that multiple bacterial 🦠strains from frogs, newts, and lizards 🐸🦎can be effective against human colon cancer in a mouse model. One particular microbe achieved a perfect response rate and survival. www.lifespan.io/news/bacteri... By: @arkadimazin.bsky.social