Gerlich Lab (@gerlichlab.bsky.social)

1/ New preprint alert! In collaboration between the Rosen, Redding, Collepardo-Guevara & Gerlich labs, we uncover a surprising principle of chromosome organisation: electrostatic repulsion positions centromeres at the chromosome surface during mitosis. 🔗 doi.org/10.1101/2025...

loading . . .

An electrostatic repulsion model of centromere organisation During cell division, chromosomes reorganise into compact bodies in which centromeres localise precisely at the chromatin surface to enable kinetochore-microtubule interactions essential for genome se... https://doi.org/10.1101/2025.09.01.673455

22 days ago