Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

This is a nice explainer of the search for Asgards happening right now off the coast of Uruguay. I was lucky enough to visit the R/V Falkor (too) [named for The NeverEnding Story!] while it was docked in Montevideo... (pics below) bsky.app/profile/c0nc...

Today's dive site, to ~2,200m. We will be streaming 9am-3pm Central. At www.youtube.com/@SchmidtOcean #AsgardArchaea @schmidtocean.bsky.social @moorefound.bsky.social @texasscience.bsky.social @utmsi.bsky.social

This team are searching for new "Asgard archaea" to sequence. Let's talk about why these bacteria-like organisms are so fascinating, why they're named for Norse mythology, and why looking at them is unlocking a better understanding of our own genomes. Once considered a type of oddball bacteria🦠...

Congratulations to the newly minted Dr. Brittney Voigt! After defending a fantastic thesis spanning work in my lab and the @edwardmarcotte.bsky.social lab.

Integrative Biology at UT is hiring an Evolutionary Biologist! Happy to answer any questions about the position/dept/UT. Come join us! integrativebio.utexas.edu cns.utexas.edu apply.interfolio.com/177547

Really enjoying watching science happen in real time, with @archaeal.bsky.social, @valdeanda.bsky.social, and colleagues live streaming their robot sub data collection from the R/V Falkor off of the coast of Uruguay

Starting at 7pm Central I will be streaming from the bottom of the ocean off the coast of Uruguay! Feel free to join and ask questions. www.youtube.com/@SchmidtOcean

Asgard collaborative expedition begins… Falkor (too) has left Montevideo

My department at UT Austin is looking to hire an Assistant Professor in Evolutionary Biology, broadly defined. Feel free to reach out to me with any questions you may have. apply.interfolio.com/177547

A wonderful collaboration between my lab and Andy Ellington and Edward Marcotte here at UT. We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)

🌍Open call: Junior Group Leader positions! Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery. Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...

Baker Lab 2025 The container is our field gear for the research expedition for Uruguay. sites.utexas.edu/baker-lab/sp...

We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

New: Researchers are broadly rejecting the Trump administration's compact. In faculty votes and student protests, they have mobilized to pressure their universities—to some effect: 6 of the original 9 universities have rejected the compact With @alexwitze.bsky.social and @jennaahart.bsky.social:

Congratulations to this year's cohort of Packard Fellows! @packardfdn.bsky.social Such a great program, especially needed in these times. www.packard.org/insights/new...

So sad to hear the news - John truly was an inspiration to so many, and one of a kind. www.cam.ac.uk/research/new...

So much fun to host @edwardmarcotte.bsky.social at the @biozentrum.unibas.ch and introduce him to the @cellarchlab.com, thanks for a wonderful Discovery Seminar!!

Delightful to finally meet you @edwardmarcotte.bsky.social and hear about your crazy cool science exploring the proteomes of all the diverse beasties on the planet to reconstruct LECA 🧪🌎. Now I see where Caitie gets it from 👨‍🔬👩‍🔬

EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬 The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩‍🔬🤓

Love #protists? Then you'd love this! Beautiful collection of hand-drawn critters represented here at the Oxford-Japan symposium on ethological dynamics in diorama environments sites.google.com/view/oxford-... #ciliates #testateamoeba #diatoms

Meet the CAGE: a newly-discovered protein nanocapsule💊, conserved from bacteria to eukaryotes! Looks more like an eclair🍩 than a prezel🥨. This protein pastry now makes us wonder- what's the filling!? Huge congrats to the ever-amazing @computingcaitie.bsky.social, now at the @biozentrum.unibas.ch 🧪🧶🧬

I am excited to share our new preprint on the CAGE complex, a mysterious hollow protein complex that I first saw years ago while surveying Tetrahymena ciliary lysate www.biorxiv.org/content/10.1... #cilia #protistsonsky 🧬🧪

The #PRETZEL is out !!! Okay the CAGE renamed now fine. Congrats @computingcaitie.bsky.social and team!!

YAYYYY, Immune systems of choano !!!! Beautiful to see how knowledge about bacterial immune systems illuminate immunology in diverse organisms with the always incredible biochemistry and structural approaches of @kranzuschlab.bsky.social. Wonderful work @yao-li.bsky.social 👏

Super excited for the full data, especially to see which of the over 400 screened binders actually got us the third place 🥳 Shout-out to the organizers for this very cool competition!

🚨The Bits to Binders Competition has concluded!🧬 One year ago we gathered scientists from around the world to design and submit protein binders that cause immune cells to target and eliminate CD20+ tumors Spoiler: They work!

Wishing a happy 83rd birthday to mathematician Karen Uhlenbeck, winner of the 2019 Abel Prize for her work applying gauge theory to four dimensional manifolds. Here is her story! tinyurl.com/ybmvcbpx #WomenInSTEM #MathSky #HistSci 🧮

‼️ Exciting new preprint from a close collaboration with Kylie Walters' group. Our study maps the binding sites of key regulators of the proteasome in situ. www.biorxiv.org/content/10.1...

Daily Bruin article about the ~800 frozen grants at UCLA including some from my lab dailybruin.com/2025/08/02/a...

We are excited to share our preprint describing DirectContacts2! Here we develop a machine learning model to discriminate between direct and indirect protein interactions. We use our model to construct a highly accurate wiring diagram of the human cell. www.biorxiv.org/content/10.1...

Scientists, please take a moment to comment on these plans to limit animal testing in drug regulation and biomedical research. Use whatever experience you have to make your comments specific to you. The law requires regulators take these comments into account, so it might help. Mine is attached.

This is great! Thank you. Can the SIB help to keep the CASP challenge running?

We will be hosting a mirror site of the CASP data and workflows at @sib.swiss. Operating a redundant site with independent funding is a good idea for important scientific infrastructure, independent from the current funding situation in the US.

Speak up to prevent a major loss for the field. CASP, which helped shaping structural biology including AlphaFold is on the verge of shutting down. NIH funding has lapsed, UC Davis support ends and the core team is being let go. Painfully shortsighted.

Congratulations to Kohl Kato and Pete Cullen and all involved in this tour de force characterising mutations in the Commander complex leading to Ritscher-Schinzel or 3C syndrome. @peterjcullen1.bsky.social www.science.org/doi/10.1126/...

Advice from NSF: grant proposals can still include outreach, community engagement, and so on. But avoid specifying particular groups

learned that the NSF indirect cost change would not retroactively alter total grant amount. Let’s say you have a funded 100K IDC grant plus 50K overhead. Total grant is 150K. If IDC changed retroactively from 50% to 15% the total grant would still be 150k.

An update on open postdoc positions, in my group and the adjacent group of Howard Ochman, here at UT-Austin. #SymbioSky Mine: insect-bacterial symbiosis with emphasis on intracellular endosymbionts and molecular mechanisms. web.biosci.utexas.edu/moran/contac...

#ASMS2025 is fast approaching, and I'm looking forward to catching up with friends and seeing a lot of great mass spectrometry research. If you’re there, check out my Tuesday talk (TOE 3:10 PM) to learn how BioPlex is enhancing drug discovery!

Very excited that our work describing hu.MAP3.0 is published in @molsystbiol.org. Here we use machine learning to integrate >25k mass spectrometry experiments to place ~70% of human proteins into 15k protein complexes. www.embopress.org/doi/full/10....

"punishing campuses by cutting health research funding would destroy the equivalent of one-quarter of annual gross domestic product in the US." jamanetwork.com/journals/jam...

hu.MAP3.0: atlas of human protein complexes by integration of >25,000 proteomic experiments #MolSystBiol #MassSpec www.embopress.org/doi/full/10....

NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.

🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees Already 14,000+ public comments, deadline is Friday 📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful Speak up! shorturl.at/WKuBj

Cutting research investment isn’t fiscally prudent. It’s economically self-defeating. www.forbes.com/sites/johndr...

What a fantastic day of science at FCBIS! @friedlab.bsky.social and I had a blast co-organizing this exciting dive into the chemistry-biology interface—great conversations, amazing energy, and a standout keynote by @edwardmarcotte.bsky.social. Thanks to all who joined us!