markus
@markusjsommer.bsky.social
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PI, Bioinformatics, NBACC Previously: Johns Hopkins Center for Computational Biology
reposted by
markus
David Stern
10 months ago
Out now in
@genomebiolevol.bsky.social
! With colleagues at NBACC and PNNL, we helped answer a long-standing question about how widely-divergent cyanobacteria produce saxitoxin, a major cause of paralytic shellfish poisoning. We assembled a new genome for a producer of saxitoxin and ...
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Novel Toxin Biosynthetic Gene Cluster in Harmful Algal Bloom-Causing Heteroscytonema crispum: Insights into the Origins of Paralytic Shellfish Toxins
Abstract. Caused by both eukaryotic dinoflagellates and prokaryotic cyanobacteria, harmful algal blooms are events of severe ecological, economic, and publ
https://academic.oup.com/gbe/article/17/1/evae248/7900804
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reposted by
markus
Steven Salzberg
10 months ago
Check out our just-published AI-based (temporal convolutional network) system, PSAURON, for predicting eukaryotic proteins, from
@markusjsommer.bsky.social
. We used a similar method in BALROG, our bacterial gene finder. Note: the "P" is silent in PSAURON 🤣
academic.oup.com/nargab/artic...
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PSAURON: a tool for assessing protein annotation across a broad range of species
Abstract. Evaluating the accuracy of protein-coding sequences in genome annotations is a challenging problem for which there is no broadly applicable solut
https://academic.oup.com/nargab/article/7/1/lqae189/7944703
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