UC Davis Health Medical Microbiology & Immunology (@ucd-mmi.bsky.social)

An evolutionary T119R substitution in the macaque T-cell immunoreceptor TIGIT enables proteolytic shedding and reveals clinical antibody vulnerabilities Despite being a promising target for cancer immunotherapy, several TIGIT (T-cell immunoreceptor with immunoglobulin and ITIM domain) antibodies have b… https://www.sciencedirect.com/science/article/pii/S0021925825028145?via%3Dihub