Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗 🦟 Transgenic parasites without Pfs230 D13D14 do not transmit 🦙 💉Nanobodies + mRNA induced antibodies reduce transmission New in @Science.org www.science.org/doi/10.1126/... #ScienceResearch #Malaria #WEHI

Pfs48/45 nanobodies block transmission 🦟 Pfs48/45 Nb-Fc reduce oocyst numbers 💎 Structure of transmission-blocking Nb with Pfs48/45 👐🏽 Bispecific Nb-Fc targeting both Pfs230 and Pfs48/45 🧑🏻‍🔬 PhD student Frankie Lyons 1st Author 🥳 Please repost and happy reading! www.biorxiv.org/content/10.1...

Stabilized PvRBP2b variants - wonderful collab with Sarel Fleishman 🔥Increased yields and thermal stability ✌️Maintains human mAb recognition 🩸Sensitivity as a sero-diagnostic for P. vivax 💕 Editors Pick 👨🏻‍🔬First paper for PhD student Jaison Please read & repost! www.jbc.org/article/S002...

Excited to share our latest work on stabilizing PvRBP2b, a key step toward P. vivax malaria diagnostics! Huge thanks and congratulations to my incredible co-authors and collaborators! Honoured that this is my first PhD publication with @thamlab.bsky.social www.jbc.org/article/S002...