Helge B. Bode (@helgebode.bsky.social)

After a long journey, we are happy to share our preprint about the biosynthesis of a new peptide deformylase inhibitor in collaboration with the Groll and Mazel labs: www.biorxiv.org/content/10.1... Please also see two related publications in bioRxiv www.biorxiv.org/content/10.1....

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Identification and biosynthesis of xildivaline, a novel and widespread peptide deformylase inhibitor from Gammaproteobacteria Xenorhabdus strains, Gram-negative bacteria pathogenic to insects and symbionts to nematodes of the genus Steinernema are prolific producers of various natural products. Here we describe the xisABCDE ... https://www.biorxiv.org/content/10.1101/2025.06.07.658423v1