Frankel Institute for Heart and Brain Health | Dr. Rosenzweig
@mmfrankel-ihbh.bsky.social
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Follow us for research updates, funding opportunities, publications, and more!
Avery Campbell, Pharmacology PhD student in the Ruas Lab, co-authored a publication titled “Novel histone deacetylase inhibitor, CS014, attenuates in vivo thrombosis while maintaining hemostasis.” Her research centers on the exploration of the myokine, Neurturin, as a potential therapeutic for ALS.
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Novel histone deacetylase inhibitor, CS014, attenuates in vivo thrombosis while maintaining hemostasis - PubMed
CS014 represents a novel HDAC inhibitor with the potential for reducing hepatotoxicity while maintaining the benefit of preventing injury-induced clotting without increased bleeding diathesis.
https://pubmed.ncbi.nlm.nih.gov/41390105/
4 days ago
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Take a look at our latest newsletter! 🫀🧠🔬
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Frankel IHBH Winter Newsletter
https://mailchi.mp/umich/frankel-ihbh-newsletter-winter2026?e=16f0f01cc9
12 days ago
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On February 6, the Frankel IHBH team participated in National Wear Red Day in honor of American Heart Month. National Wear Red Day supports awareness about heart disease, the leading cause of death for Americans, particularly women, and encourage heart-healthy actions! 🫀👚
25 days ago
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Seminar alert! 🔔 Please join us for the next M-BoCA Seminar tomorrow, Tuesday, February 17th, from 12:00pm-1:00pm featuring Jorge Ruas, PharmD, PhD, presenting “HECTD1 couples sarcomere integrity to mitochondrial function in striated muscle". Join seminar:
umich.zoom.us/j/91235361341
28 days ago
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Red Shirt Day is coming up! Cardiovascular disease is the No. 1 killer of women. On February 6, wear red to be seen, to be counted, to be heard, and to make an impact. Together, we are stronger than heart disease and stroke.
about 2 months ago
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Missed our latest newsletter? Check it out here!
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Frankel IHBH Autumn Newsletter
https://mailchi.mp/umich/frankel-ihbh-newsletter-autumn2025
about 2 months ago
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Join us on National
#WearRedDay
Feb. 6 to raise awareness about
#HeartDisease
, the leading cause of death in the U.S. Devoting a little time every day to care for yourself can go a long way toward protecting your heart health! 🫀💪
#OurHearts
#HeartMonth
www.nhlbi.nih.gov/ourhearts
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OurHearts
#OurHearts is an inspiring way for The Heart Truth® to encourage and motivate everyone to adopt heart-healthy behaviors, together. Research shows having social
https://www.nhlbi.nih.gov/ourhearts
about 2 months ago
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Dr. Rosenzweig will be presenting at the Michigan State University Grand Rounds on Tuesday, November 25 from 12:00-1:00pm. We encourage attending his talk, "Aging-related Pathways in Heart Failure: Not Just for the Old" over zoom!
msu.zoom.us/j91450803106
4 months ago
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On November 17 & 18, Dr. Arianne Caudal will be visiting the institute from Stanford University where she will present her Seminar and Chalk Talk. We encourage you to join via zoom! Research Seminar: Meeting ID: 942 0047 5060 Passcode: 937179 Chalk Talk: Meeting ID: 995 9840 1814 Passcode: IHBH
4 months ago
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Today we welcome Dr. Koleini, MD, Ph.D. from Johns Hopkins University, to the Frankel IHBH, where he will present his research seminar and chalk talk! 🎉
5 months ago
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Dr. Ruas will be speaking at the annual Daniel Goldstein, MD M-BoCA Symposium today with his talk: "Exercising Immunity: How muscle communicates with immune cells and the tissues they target" Dr. Rosenzweig will be presenting the FY25 Multidisciplinary Pilot Award winners at the end of the event.
5 months ago
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Check out the article overview of Dr. Rosenzweig's latest publication "Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α":
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5 months ago
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Dr. Rosenzweig recently had an article published in Natured Cardiovascular Research: "Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α." Read the article here:
www.nature.com/articles/s44...
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Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α - Nature Cardiovascular Research
Khetarpal et al. show that the metabolic regulator PGC-1α is essential in heart muscle cells for exercise-driven cardiac growth, and that suppression of the stress-induced myokine GDF15 is required to enable cardiomyocyte adaptations to training.
https://www.nature.com/articles/s44161-025-00712-3
6 months ago
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Congratulations to more of our awardees for the Director's Innovation Fund! 🥳🎉 Alison Affinati, MD, Ph.D. and Laurie Svoboda, Ph.D.
7 months ago
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We recently completed the selection process for the first round of the Frankel IHBH Director’s Innovation Early Career Awards. Thank you to all who applied and to our reviewers! The awardees are: Toshiro Hara, Ph.D. and Sasha Cai Lesher-Pérez, Ph.D. Andrew Tidball, Ph.D.
8 months ago
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Catch up with the Frankel IHBH and view our summer newsletter! 🫀🧠🔬
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Frankel IHBH Summer Newsletter
https://mailchi.mp/umich/frankel-ihbh-newsletter-summer2025
8 months ago
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Check out our Spring Newsletter here! 🫀🧠🔬
mailchi.mp/umich/franke...
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Frankel IHBH Spring Newsletter
https://mailchi.mp/umich/frankel-ihbh-newsletter-winter2025-12926254?e=[UNIQID]
11 months ago
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Join us this week for a Research Seminar and Chalk Talk presented by Dr. Anthony Verkerke, of Beth Israel Deaconess Medical Center, Harvard Medical School. Zoom Details below: April 9th Seminar Meeting ID: 997 4275 4262 Passcode: IHBH April 10th Chalk Talk Meeting ID: 973 5629 7986 Passcode: IHBH
11 months ago
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Tomorrow, April 3, at 9:00am, Dr. Rosenzweig will be giving a talk at the University of Washington titled: "Exercise as a Discovery Platform for New Therapeutic Targets in Heart Failure" Click the link below to join via Zoom!
urldefense.com/v3/__https:/...
12 months ago
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Over the weekend, Dr. Rosenzweig attended ACC 25 in Chicago, where he had the opportunity to co-chair a session and present his talk focused on heart-brain interactions titled “Cardio-Neurology: Does Optimizing Cardiovascular Health Improve Cognitive Health?”
@accintouch.bsky.social
#ACC25
🫀🧠
12 months ago
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Did you know that the first Friday in February is National Wear Red Day? Wear red and encourage others to do the same to help raise awareness that heart disease is the leading cause of death in the U.S., and largely preventable. ❤️🫀
about 1 year ago
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Check out the latest edition of the Cardio-Cognition newsletter! 🫀🧠🥼
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Frankel IHBH Winter Newsletter
https://mailchi.mp/umich/frankel-ihbh-newsletter-winter2025
about 1 year ago
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We've just joined Bluesky! 🥳 Follow us for research updates, publications, the quarterly Cardio Cognition Newsletter, and more. 🔬🧠🫀
about 1 year ago
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