🗣️💬Thank you to everyone who attended the Frankel IHBH Inaugural Speaker Series featuring Filip Swirski, PhD, from Mount Sinai. Dr. Swirski presented his talk “A cholesterol handling macrophage circuit that modulates cardiometabolic disease” along with a story about heart-brain connections. 🫀+🧠

Thank you to everyone who made the Spring AHA SFRN on Inflammation meeting at the University of Michigan a success!🎉We’re grateful to the American Heart Association for supporting the outstanding science and collaboration emerging from this Network.🫀🧠 #AmericanHeartAssociation

Thank you to everyone who made the Spring AHA SFRN on Inflammation meeting at the University of Michigan a success!🎉We’re grateful to the American Heart Association for supporting the outstanding science and collaboration emerging from this Network.🫀🧠 #AmericanHeartAssociation

On Saturday, May 16, the Frankel IHBH team participated in the 2026 Washtenaw County Heart and Stroke Walk & 5K!🫀🧠🏃‍➡️The walk raised over $257,000 to support lifesaving research and education for heart disease and stroke. Thank you to everyone who participated!🎉#HeartWalk #AmericanHeartAssociation

🔔Check out the recent issue of the Cardio-Cognition Newsletter from the Frankel IHBH! 🧠🫀 Featuring highlights from our faculty, labs, and the Michigan Medicine community!🎉 @anthony-rosenzweig.bsky.social

Today!🎉📢 The Frankel IHBH is hosting its Inaugural Director’s Speaker Series with a lecture by Filip K. Swirski, PhD, Director of the Cardiovascular Research Institute at Icahn School of Medicine at Mount Sinai. We hope to see you there!🫀🧠

Today!🎉📢 The Frankel IHBH is hosting its Inaugural Director’s Speaker Series with a lecture by Filip K. Swirski, PhD, Director of the Cardiovascular Research Institute at Icahn School of Medicine at Mount Sinai. We hope to see you there!🫀🧠

Michigan Medicine community! 📢 The Frankel IHBH is hosting its Inaugural Director’s Speaker Series with a lecture by Filip K. Swirski, PhD, Director of the Cardiovascular Research Institute at Icahn School of Medicine at Mount Sinai. See the attached flyer for the full event details! 🧠🫀🎉

📖🎉Check out the full story highlighting the recipients of the Heart-Brain-Diabetes Interdisciplinary Studies program from the Frankel IHBH, Caswell Diabetes Institute, and the Michigan Diabetes Research Center!🫀🧠🔬

🎉Congrats to Aurel Leuchtmann, PhD (Ruas Lab), inaugural Frankel IHBH Postdoctoral Fellow! Awarded annually, this fellowship supports innovative heart/brain health research. His work aims to guide pharmacological and non-pharmacological ways to prevent, halt, or reverse heart remodeling.🫀🧠

🎉Congrats to Aurel Leuchtmann, PhD (Ruas Lab), inaugural Frankel IHBH Postdoctoral Fellow! Awarded annually, this fellowship supports innovative heart/brain health research. His work aims to guide pharmacological and non-pharmacological ways to prevent, halt, or reverse heart remodeling.🫀🧠

🫀🧠100’s of new candidate biomarkers and therapeutic targets linking heart and brain disease in: “Large-scale identification of protein biomarkers and therapeutic targets in heart and brain disease” (Wu; Li) (Nature Cardiovascular Research) Look up your favorite protein and share it with us! 🔬

Out now!🎉Congrats to Chao Wu, MD, PhD (Rosenzweig Lab) and partners incl. Chunyu Li (Wang Lab) on “Large-scale identification of protein biomarkers and therapeutic targets in heart and brain disease” (Nature Cardiovascular Research) The study maps heart-brain links via plasma proteins as biomarkers.

🫀🧠100’s of new candidate biomarkers and therapeutic targets linking heart and brain disease in: “Large-scale identification of protein biomarkers and therapeutic targets in heart and brain disease” (Wu; Li) (Nature Cardiovascular Research) Look up your favorite protein and share it with us! 🔬

Out now!🎉Congrats to Chao Wu, MD, PhD (Rosenzweig Lab) and partners incl. Chunyu Li (Wang Lab) on “Large-scale identification of protein biomarkers and therapeutic targets in heart and brain disease” (Nature Cardiovascular Research) The study maps heart-brain links via plasma proteins as biomarkers.

The Challenger Foundation Career Development Award inaugural recipient Dr. Qiulian Zhou, PhD, will use genetic models to study why HFpEF affects women more. This award is aimed to accelerate cardiovascular research and career development, focusing on sex-based disparities in heart disease.

The Frankel IHBH, Elizabeth Weiser Caswell Diabetes Institute, and the Michigan Diabetes Research Center, are delighted to share the winners of the Heart-Brain-Diabetes Interdisciplinary Studies Program: Nadejda Bozadjieva Kramer, PhD and Roger L. Albin, MD Jun Wu, PhD and Alison Affinati, MD, PhD

Avery Campbell, Pharmacology PhD student in the Ruas Lab, co-authored a publication titled “Novel histone deacetylase inhibitor, CS014, attenuates in vivo thrombosis while maintaining hemostasis.” Her research centers on the exploration of the myokine, Neurturin, as a potential therapeutic for ALS.

Avery Campbell, Pharmacology PhD student in the Ruas Lab, co-authored a publication titled “Novel histone deacetylase inhibitor, CS014, attenuates in vivo thrombosis while maintaining hemostasis.” Her research centers on the exploration of the myokine, Neurturin, as a potential therapeutic for ALS.

Take a look at our latest newsletter! 🫀🧠🔬 mailchi.mp/umich/franke...

On February 6, the Frankel IHBH team participated in National Wear Red Day in honor of American Heart Month. National Wear Red Day supports awareness about heart disease, the leading cause of death for Americans, particularly women, and encourage heart-healthy actions! 🫀👚

Seminar alert! 🔔 Please join us for the next M-BoCA Seminar tomorrow, Tuesday, February 17th, from 12:00pm-1:00pm featuring Jorge Ruas, PharmD, PhD, presenting “HECTD1 couples sarcomere integrity to mitochondrial function in striated muscle". Join seminar: umich.zoom.us/j/91235361341

Red Shirt Day is coming up! Cardiovascular disease is the No. 1 killer of women. On February 6, wear red to be seen, to be counted, to be heard, and to make an impact. Together, we are stronger than heart disease and stroke.

Missed our latest newsletter? Check it out here! mailchi.mp/umich/franke...

Join us on National #WearRedDay Feb. 6 to raise awareness about #HeartDisease, the leading cause of death in the U.S. Devoting a little time every day to care for yourself can go a long way toward protecting your heart health! 🫀💪 #OurHearts #HeartMonth www.nhlbi.nih.gov/ourhearts

Dr. Rosenzweig will be presenting at the Michigan State University Grand Rounds on Tuesday, November 25 from 12:00-1:00pm. We encourage attending his talk, "Aging-related Pathways in Heart Failure: Not Just for the Old" over zoom! msu.zoom.us/j91450803106

On November 17 & 18, Dr. Arianne Caudal will be visiting the institute from Stanford University where she will present her Seminar and Chalk Talk. We encourage you to join via zoom! Research Seminar: Meeting ID: 942 0047 5060 Passcode: 937179 Chalk Talk: Meeting ID: 995 9840 1814 Passcode: IHBH

Today we welcome Dr. Koleini, MD, Ph.D. from Johns Hopkins University, to the Frankel IHBH, where he will present his research seminar and chalk talk! 🎉

Dr. Ruas will be speaking at the annual Daniel Goldstein, MD M-BoCA Symposium today with his talk: "Exercising Immunity: How muscle communicates with immune cells and the tissues they target" Dr. Rosenzweig will be presenting the FY25 Multidisciplinary Pilot Award winners at the end of the event.

Check out the article overview of Dr. Rosenzweig's latest publication "Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α":

Dr. Rosenzweig recently had an article published in Natured Cardiovascular Research: "Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α." Read the article here: www.nature.com/articles/s44...

Congratulations to more of our awardees for the Director's Innovation Fund! 🥳🎉 Alison Affinati, MD, Ph.D. and Laurie Svoboda, Ph.D.

We recently completed the selection process for the first round of the Frankel IHBH Director’s Innovation Early Career Awards. Thank you to all who applied and to our reviewers! The awardees are: Toshiro Hara, Ph.D. and Sasha Cai Lesher-Pérez, Ph.D. Andrew Tidball, Ph.D.

Catch up with the Frankel IHBH and view our summer newsletter! 🫀🧠🔬 mailchi.mp/umich/franke...

Check out our Spring Newsletter here! 🫀🧠🔬 mailchi.mp/umich/franke...

Join us this week for a Research Seminar and Chalk Talk presented by Dr. Anthony Verkerke, of Beth Israel Deaconess Medical Center, Harvard Medical School. Zoom Details below: April 9th Seminar Meeting ID: 997 4275 4262 Passcode: IHBH April 10th Chalk Talk Meeting ID: 973 5629 7986 Passcode: IHBH

Tomorrow, April 3, at 9:00am, Dr. Rosenzweig will be giving a talk at the University of Washington titled: "Exercise as a Discovery Platform for New Therapeutic Targets in Heart Failure" Click the link below to join via Zoom! urldefense.com/v3/__https:/...

Over the weekend, Dr. Rosenzweig attended ACC 25 in Chicago, where he had the opportunity to co-chair a session and present his talk focused on heart-brain interactions titled “Cardio-Neurology: Does Optimizing Cardiovascular Health Improve Cognitive Health?” @accintouch.bsky.social #ACC25 🫀🧠

Did you know that the first Friday in February is National Wear Red Day? Wear red and encourage others to do the same to help raise awareness that heart disease is the leading cause of death in the U.S., and largely preventable. ❤️🫀

Check out the latest edition of the Cardio-Cognition newsletter! 🫀🧠🥼

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