Manhart Lab
@carolmanhart.bsky.social
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Studying DNA Repair at Temple University
Congratulations to third year graduate students Yasmine Sakinejad and Amruta Bhalkar on successfully elevating to Ph.D. candidacy! Woohoo!!
about 1 year ago
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Check out the preprint of our latest work:
www.biorxiv.org/content/10.1...
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The mismatch repair factor Mlh1-Pms1 uses ATP to compact and remodel DNA
In eukaryotes, mismatch repair begins with MutS homolog (MSH) complexes, which scan newly replicated DNA for mismatches. Upon mismatch detection, MSH complexes recruit the PCNA- stimulated endonucleas...
https://www.biorxiv.org/content/10.1101/2025.01.16.633381v1
about 1 year ago
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